A5080368245- Acute Myocardial Infarction Research
- Coronary Interventions and Diagnostics
- Cardiac Imaging and Diagnostics
- Antiplatelet Therapy and Cardiovascular Diseases
- Telemedicine and Telehealth Implementation
- Cardiac Health and Mental Health
- Cardiovascular Function and Risk Factors
- Diabetes Treatment and Management
- Heart Failure Treatment and Management
- Pharmaceutical Economics and Policy
- COVID-19 and healthcare impacts
- Healthcare Systems and Public Health
- Hematological disorders and diagnostics
- Healthcare Quality and Management
- Blood Pressure and Hypertension Studies
- Healthcare Systems and Technology
- Radiation Dose and Imaging
- Cardiac Fibrosis and Remodeling
- Global Public Health Policies and Epidemiology
- Renin-Angiotensin System Studies
- Lipoproteins and Cardiovascular Health
- COVID-19 Clinical Research Studies
- Peripheral Artery Disease Management
- Protease and Inhibitor Mechanisms
- Biosimilars and Bioanalytical Methods
National Heart Institute
2020-2025
Benha University
2024
Ain Shams University
2024
Assistance Publique – Hôpitaux de Paris
2019-2022
Hôpital Bichat-Claude-Bernard
2019-2022
Université Paris Cité
2019-2022
Abstract Background Health awareness plays a major role in determining the outcomes of serious medical conditions especially when response time is crucial. STEMI (ST-segment elevation myocardial infarction) patients are prone to compilations if they do not receive appropriate treatment on time. Many factors affect health community, including educational level, previous exposure similar situations, and materials. Those who know symptoms infarction will present late hospital exposed higher...
The renin-angiotensin-aldosterone system (RAAS) plays a pivotal role in regulating blood pressure (BP), with dysregulation of RAAS resulting hypertension and potentially heart failure (HF), myocardial infarction (MI), cardio-renal syndrome, stroke. inhibitors, such as angiotensin-converting enzyme inhibitors (ACEis) angiotensin receptor blockers (ARBs), have advantages beyond BP control. However, differences between these two drug classes need to be considered when choosing therapy for...
In percutaneous coronary intervention (PCI) procedures for patients with unprotected left main artery (ULMCA) lesions, intravascular ultrasonography (IVUS) guidance has shown potential enhancing clinical outcomes. However, studies confirming its superiority to conventional angiographic-guided PCI remain few. This study aimed assess if IVUS-guided LMCA stenosis improves outcomes compared PCI.
Abstract Aims In Europe, global data on guideline adherence, geographic variations, and determinants of clinical events in patients with chronic coronary syndrome (CCS) remain suboptimal. The European Society Cardiology (ESC) EURObservational Research Programme (EORP) Chronic Ischemic Cardiovascular Disease Long-Term (CICD-LT) registry is a prospective registry, was designed to describe the profile, management, outcomes CCS across ESC countries. Methods results We aimed investigate at 1-year...
Abstract Background: Coronary artery disease (CAD) is a leading cause of mortality worldwide, with varying patterns and risk factors across different age groups. While CAD common in older adults, data on young adults are limited, traditional familial history playing significant role early development. The purpose this study was to compare the coronary angiographic (<40 years) (≥40 presented CAD, assess correlation factors, monitor clinical outcomes after 1 year. Patients Methods: This...
COVID-19 is a global pandemic that spread rapidly around the world. It led to changes in management plans for different diseases due occupation of health services and staff with COVID battel, addition lockdown consequences. Cardiac emergency management, such as ST-segment elevation myocardial infarction, was affected at multiple levels by pandemic, including delay patients' threshold call medical services, decreased availability ambulances, increased waiting time departments, percutaneous...
Abstract Background The Secondary Manifestations of Arterial Disease (SMART) risk score was recommended by the European Society Cardiology (ESC) to estimate a 10-year for myocardial infarction, stroke, or vascular death in individual patients with clinically manifested atherosclerotic disease (ASCVD).(1) An updated SMART2 algorithm developed and recalibrated according population risks different world regions except Africa. expected-observed ratio recurrent ASCVD very high-risk region study...
Abstract Background This study aims at identifying if there is a role for Sodium glucose co- transporter 2 inhibitors (SGLT2i) in the event of acute myocardial infarction. Patients who presented with anterior ST- elevation infarction (STEMI) & had undergone successful primary percutaneous coronary intervention left descending were randomized into group control group. The received dapagliflozin 10 mg once daily. endpoint was cardiac function assessed by both; biomarker (i.e.: N-terminal...
Abstract Background There is a paucity of data regarding the clinical characteristics, management practices and burden disease in patients (pts) with HF, assessment which may help understanding treatment gaps facilitating best possible HF care. Aim objectives The cohort iCaReMe (NCT03549754) aims to describe profile, patterns, comorbidities pts HF. Methods This prospective, investigator-led, multinational, cloud-based, observational registry enrolled eligible adults T2D, HTN and/or CKD...
Abstract Background Acute coronary syndrome (ACS) patients are vulnerable to anxiety and depression. This study aimed assess the mental health burden among Egyptian ACS by assessing prevalence associates of these conditions. enrolled 212 who underwent angiogram. Anxiety depression were assessed using Hospital Depression Scale (HADS). Demographic, psychosocial, clinical data collected. Univariate multivariate logistic regression analyses identified factors associated with Results The mean age...
Abstract Background Till the moment of this document writing, no Egyptian consensus is there to guide selection additional antithrombotic in stable patients with established CVD. Despite use lifestyle measures and statins, those CVD still face a considerable burden residual risk. Main body With evolvement evidence-based medicine, have been lot recommendations medications maximize protection for patients. Accordingly, Society Cardiology working group thrombosis prevention took responsibility...
Previous research has linked an imbalance of the tissue inhibitors metalloproteinase-1 (TIMP-1) and fibronectin (FN) to heart failure as a part extracellular matrix network (ECM) biochemistry profile, which is vital for cardiac homeostasis.This study aimed assess diagnostic performance FN, TIMP-1, CK-MB in (HF).Sixty patients (45 with acute 15 chronic HF) were recruited.Thirty individuals (20 ischemic diseases, other 10 healthy individuals) recruited control group.The biotin double antibody...
Cardiovascular diseases are the leading cause of death worldwide. Ticagrelor is an oral antiplatelet drug used in acute coronary syndrome. Although generic drugs approved for their bioequivalence to original product, they not necessarily be therapeutically equivalent. This study was conducted prove efficacy and safety ticagrelor generically named Ticaloguard® compared its brand Brilique® healthy volunteers. A loading dose 180 mg or followed by a 90 twice daily regimen as maintenance given 14...
Abstract Background CAD accounts for approximately 42% of all cardiovascular deaths. A lot predisposing risk factors exist and they are generally divided into modifiable non-modifiable factors. Genetic variants were found to be among the where strongly contribute incidence in Egyptian populations. Purpose highlighting different genetic polymorphisms Egyptians ranking them according degree importance. Methods Intensive research was done period between 15 May 2018 September on both Science...
Background: The failure of the saphenous vein graft (SVG) is a critical flaw in coronary artery bypass grafting (CABG) that has been associated with bad cardiac outcomes such as necessity to repeat revascularization, recurrent angina, myocardial infarction, and mortality.Objective: To compare mid-term patency used for revascularization RCA when anastomosed Distal Right Coronary Artery (DRCA) versus Posterior Descending (RPDA) proximal lesion patients who underwent isolated CABG.Patients...
Purpose: Telemedicine is representing the future of medical services. It shows many advantages and promising opportunities. has been tried in different specialties. The COVID-19 pandemic enhanced establishment telemedicine services worldwide. Low middle income countries such as Egypt are still new to these technologies. purpose this study provide a snapshot data on current situation assess its transition towards more integrated from physicians' perspective.
 Methodology: This cross...
Purpose: The regularly used contrast media in the angiography procedures and interventions are known to carry certain risks patient. This includes allergy, nephrotoxicity, pulmonary edema. Additionally, radiation exposure is associated with high bone marrow depression, infertility, other hazards. purpose of study was compare Dynamic Roadmap technology regular coronary intervention regarding exposure, fluoroscopy time, incidence Contrast Induced Nephropathy.
 Methodology: Observational...
Introduction: Despite the shift in PCI application, underlying criteria of complex and its impact on clinical outcomes remain unexplained.Methods: Single-center retrospective observational study characteristics 1-year outcome.Complex was defined as any following: three-vessel disease, bifurcation lesion, left main moderate to severe calcification by angiography CTO.Results: The cohort includes 551 patients who had over a two-month period.101 (20%) all fulfilled for PCI: 20% have 3VD, 33% LM...
Abstract Aims Acute myocardial infarction (AMI) represents a huge health burden and growing economical challenge, particularly with recurrent major adverse cardiovascular events (MACE). Large attention is critically mandated to identify population at higher risk for MACE maximize secondary preventive measures. This study aimed evaluate the utility of residual SYNTAX Score (RSS) after percutaneous coronary intervention (PCI) culprit vessel(s) in patients AMI (STEMI or NSTEMI) predict 6-months...
Introduction: Heart failure (HF) is a leading global health problem affecting more than 64 million people worldwide. Co-existing cardiovascular renal and metabolic (CVRM) diseases confer poorer prognosis with an increased risk of outcomes. Although Middle East Africa (MEA) region bears disproportionately high burden CVRM diseases, there scarcity real-world data on patients’ characteristics, factors, management practices. Aims: To describe the clinical features, comorbidities, treatment...
<sec> <title>BACKGROUND</title> Telemedicine is representing the future of medical services. It shows many advantages and promising opportunities. has been tried in different specialties. The COVID-19 pandemic enhanced establishment telemedicine services worldwide. Low middle-income countries such as Egypt are still new to these technologies. </sec> <title>OBJECTIVE</title> Provide a snapshot data on current situation assess its transition towards more integrated from physicians'...