A5021243413- High Entropy Alloys Studies
- 2D Materials and Applications
- High-Temperature Coating Behaviors
- Lipid metabolism and biosynthesis
- MXene and MAX Phase Materials
- Microbial Metabolic Engineering and Bioproduction
- Photosynthetic Processes and Mechanisms
- Advanced materials and composites
- Graphene research and applications
- Advancements in Battery Materials
- RNA Research and Splicing
- Plant biochemistry and biosynthesis
- Extracellular vesicles in disease
- Boron and Carbon Nanomaterials Research
- Concrete and Cement Materials Research
- RNA Interference and Gene Delivery
- Blind Source Separation Techniques
- Gas Sensing Nanomaterials and Sensors
- Advanced Battery Materials and Technologies
- Speech and Audio Processing
- Advanced Adaptive Filtering Techniques
- Pharmaceutical and Antibiotic Environmental Impacts
- Chalcogenide Semiconductor Thin Films
- Intermetallics and Advanced Alloy Properties
- Metal and Thin Film Mechanics
University of California, Berkeley
2020-2025
Institute of Biophysics
2013-2024
Chinese Academy of Sciences
2013-2024
East China Normal University
2019-2024
Shaoxing University
2022-2024
Howard Hughes Medical Institute
2022-2023
Southern University and Agricultural and Mechanical College
2019-2022
University of Chinese Academy of Sciences
2013-2022
North China Electric Power University
2022
University of Louisville
2017-2021
Abstract Lipid droplets (LDs) are multi-functional organelles consisting of a neutral lipid core surrounded by phospholipid monolayer, and exist in organisms ranging from bacteria to humans. Here we study the functions LDs oleaginous bacterium Rhodococcus jostii . We show that these bind genomic DNA through major LD protein, MLDS, which increases survival rate bacterial cells under nutritional genotoxic stress. MLDS expression is regulated transcriptional regulator, MLDSR, binds operator...
The dissemination and propagation of antibiotic resistance genes (ARGs) is an emerging global health concern, the potential effects nanomaterials on ARGs fates have drawn much attention recently. In current study, metallic nanoparticles occurrence leachate culturable microbiota were investigated by four typical metal oxide (Cu, Zn, CuO, ZnO). diversity was remarkably decreased during cultivation enrichment microbiota, their abundances for 1.4–3.2 orders magnitude. presence facilitated...
ABSTRACT Lipid droplets (LDs) are ubiquitous organelles that serve as a neutral lipid reservoir and hub for metabolism. Manipulating LD formation, evolution, mobilization in oleaginous species may lead to the production of fatty acid-derived biofuels chemicals. However, key factors regulating dynamics remain poorly characterized. Here we purified LDs identified LD-associated proteins from cells lipid-producing yeast Rhodosporidium toruloides cultured under nutrient-rich, nitrogen-limited,...
To completely understand lithium adsorption, diffusion, and capacity on the surface of phosphorene and, therefore, prospects as an anode material for high-performance lithium-ion batteries (LIBs), we carried out density-functional-theory calculations studied adsorption energy landscape, diffusion mobility, intercalation, phosphorene. We also out, very first time, experimental measurement Our show that mobility along zigzag direction in valley was about 7 to 11 orders magnitude faster than...
Inorganic Na-ion superionic conductors play a vital role in all-solid-state Na batteries that operate at room temperature. Sodium thioantimonate (Na3SbS4), popular sulfide-based solid electrolyte, has attracted serious attention due to its advantages of high ionic conductivity temperature and impressive chemical stability under ambient conditions. Much research detailing Na3SbS4 focused on synthetic approaches interfacial against metal, yet, there is limited information elucidating...
In this study, refractory high entropy alloys (RHEAs) Mo20Nb20Re20Ta20W20, Mo15Nb20Re15Ta30W20, and Mo15Nb20Re10Ta35W20 were studied by applying the first-principles density functional theory (DFT) method. The DFT calculation was based on a large unit cell model of 100-atom supercell, with randomly distributed five element atoms. mechanical properties all three RHEAs calculated compared. Comparing other two RHEAs, Mo15Nb20Re15Ta30W20 possesses balanced an optimized concentration expensive Re...
Much attention has been focused on the possibility that cytoplasmic proteins and RNA may be conveyed between cells in extracellular vesicles (EVs) tunneling nanotube (TNT) structures. Here, we set up two quantitative delivery reporters to study cargo transfer cells. We found EVs are internalized by reporter but do not efficiently deliver functional Cas9 protein nucleus. In contrast, donor acceptor co-cultured permit cell contact resulted a highly effective transfer. Among our tested pairs,...
Lipid droplets (LDs) are the main fat storing sites in almost all species from bacteria to humans. The perilipin family has been found as LD proteins mammals, Drosophila, and a couple of slime molds, but no bacterial containing sequence conservation were identified. In this study, we reported that hydroxysteroid dehydrogenase (HSD) was on LDs across organisms by proteomic analysis. Imaging experiments confirmed targeting three representative HSD including ro01416 RHA1, DHS-3 C. elegans,...
Hardness is an essential property in the design of refractory high entropy alloys (RHEAs). This study shows how a neural network (NN) model can be used to predict hardness RHEA, for first time. We predicted several alloys, including novel C0.1Cr3Mo11.9Nb20Re15Ta30W20 using NN model. The from was consistent with available experimental results. prediction verified by experimentally synthesizing and investigating its microstructure properties hardness. provides alternative route determine Vickers RHEAs.
Refractory high-entropy alloys (RHEAs) Al20+xCr20-xMo20-yTi20V20+y ((x, y) = (0, 0), 10), and (10, 15)) were computationally studied to obtain a low density better mechanical property. The functional theory (DFT) method was employed compute the structural properties of alloys, based on large unit cell model randomly distributed elements. Debye–Grüneisen used study thermal Al20+xCr20-xMo20-yTi20V20+y. phase diagram calculation shows that all three RHEAs have single body-centered cubic (BCC)...
A comprehensive first-principles calculation has been carried out revealing that at sufficiently high Li concentration and certain well-defined configurations a phase transition from black to blue phosphorene can take place. Blue phosphorene, newly predicted allotrope of phosphorus, possesses unique crystalline electronic structure is promising candidate, not only for fundamental research but also optoelectronic applications. Methods growing high-quality layers are highly desirable...
Refractory complex concentrated alloys (RCCAs) have drawn increasing attention recently owing to their balanced mechanical properties, including excellent creep resistance, ductility, and oxidation resistance. The thermal properties of RCCAs are directly linked with the elastic constants. However, it is time consuming expensive obtain constants conventional trial-and-error experiments. predicted using a combination density functional theory simulation data machine learning (ML) algorithms in...
In this study, bilayer phosphorene samples were subjected to high pressure using a Diamond Anvil Cell (DAC) and their vibrational properties studied via in situ Raman spectroscopy. Systematic shifting the frequency of A1g, B2g, A2g modes was observed theoretical calculations performed understand relationship between strain properties. The changes vibration under are found reflect deformation structure its stiffness. Firstly, study shows substantial pressure-induced enhancement interactions...
Phosphorene-based field effect transistor (FET) structures were fabricated to study the gas- and photo-detection properties of phosphorene. The interplay between device performance environmental conditions was probed analyzed using in situ transport measurements. exposed different chemical light environments understand how they perform under external stimuli. For gas/molecule detection studies, inert (Ar), as well as, oxidizing (N2O), reducing (H2 also N2H4) agents selected. FET structure...
Refractory high entropy alloys (RHEAs) have been proven to be a potential candidate in the biomedical field due their balanced mechanical properties and biocompatible composition. Recent experimental findings show that RHEAs like HfNbTaTiZr Hf0.5Nb0.5Ta0.5Ti1.5Zr good such as polarization wear resistance than others which establish them materials for application. In this work, we performed first-principles density functional theory calculations on thermal of Hf0.5Nb0.5Ta0.5Ti1.5Zr. The...
Owing to its importance the assessment and design of reinforced concrete structures, it is essential determine chloride diffusivity concrete. This paper develops a random walk algorithm for with aggregate shape effect. In this algorithm, an equivalent model established by coating each particle interfacial transition zone (ITZ) layer ITZ thickness estimated through stereological analysis. The then formulated effective medium approximation. Finally, adopted compute After validity simulation...
Foamed porous cement materials were fabricated with H