A5061403986- Dementia and Cognitive Impairment Research
- Migraine and Headache Studies
- Endometrial and Cervical Cancer Treatments
- Human-Automation Interaction and Safety
- Trigeminal Neuralgia and Treatments
- Nutritional Studies and Diet
- Autonomous Vehicle Technology and Safety
- Traffic and Road Safety
- Botulinum Toxin and Related Neurological Disorders
- Nutrition and Health in Aging
- Frailty in Older Adults
- Cervical Cancer and HPV Research
- Ovarian cancer diagnosis and treatment
- Sleep and related disorders
- Older Adults Driving Studies
- Cardiovascular Syncope and Autonomic Disorders
- Sympathectomy and Hyperhidrosis Treatments
- Diet and metabolism studies
- Alzheimer's disease research and treatments
- Multiple Sclerosis Research Studies
- Gynecological conditions and treatments
- Health and Well-being Studies
- Intraoperative Neuromonitoring and Anesthetic Effects
- Mosquito-borne diseases and control
- Health Systems, Economic Evaluations, Quality of Life
National and Kapodistrian University of Athens
2013-2024
Satways (Greece)
2024
LETO Maternity Hospital
2024
Eginition Hospital
2012-2021
General University Hospital of Patras
2020
Alexandra Hospital
2014-2017
Hippocration General Hospital
2016
Space Hellas (Greece)
2016
Providence College
2012
Pammakaristos Hospital
2012
Subjective cognitive decline may reflect a dementia prodrome or modifiable risk factor such as sleep disturbance. What is the association between and subjective decline? Cross-sectional design, from two studies of older adults: WHICAP in USA HELIAD Greece. A total 1,576 1,456 participants, without mild impairment, severe depression/anxiety, were included. Participants mostly women, with 12 (WHICAP) 8 (HELIAD) mean years education. Sleep problems estimated using Scale Medical Outcomes Study....
Introduction: Study of the epidemiology dementia to gain insight into putative predisposing and prophylactic factors is first step toward establishing effective preventive therapeutic strategies for this ever-growing public health problem. Relevant data in Greece are scattered outdated. Methods: We investigated prevalence as part a population-representative epidemiological study [Hellenic Longitudinal Investigation Aging Diet (HELIAD)] 2 Greek regions. Results: Our sample comprised 1792...
Background To identify the preferences and perceptions of migraine patients for acute preventive treatment options to investigate which outcomes are most important.
Dietary intervention is an enticing approach in the fight against cognitive impairment. Nutritional supplements and dietetic counseling are relatively easy benign interventions, but research has not yet yielded irrefutable evidence as to their clinical utility. Heterogeneity results of available studies, well methodological practical issues, does allow replication generalization findings. The paper at hand reviews only randomized trials single nutrients, multi-nutrient formulations dietary...
Introduction: Timely recognition of mild cognitive impairment (MCI) is essential in optimizing prevention and treatment for Alzheimer disease. Because the paucity data on MCI epidemiology Greece variability worldwide published results, we investigated prevalence determinants elderly population Greece. Methods: As part Hellenic Epidemiological Longitudinal Investigation Aging Diet (HELIAD), randomly selected 1960 individuals 65 years older to undergo full neurological neuropsychological...
Migraine is included in the top-ten disabling diseases and conditions among Western populations. Non-invasive neurostimulation, including Cefaly® device, for treatment of various types pain a relatively new field interest. The aim present study was to explore clinical experience with cohort migraine patients previously refractory or intolerant topiramate prophylaxis. A prospective, multi-center performed diagnosed episodic chronic previous failure requiring prevention according treating...
Objective: To estimate the prevalence of frailty using five different instruments in a cohort older adults and explore association between various risk factors. Method: 1,867 participants aged 65 years above were included current retrospective cross-sectional study. Frailty was operationalized according to Fried definition, FRAIL Scale, Index (FI), Tilburg Indicator (TFI), Groningen (GFI). We explored role factors logistic regression analyses. Results: The varied depending on definition used...
Objectives We studied the prevalence of subjective cognitive decline (SCD) and its determinants in a sample 1456 cognitively normal Greek adults ≥65 years old. Methods/design Subjects were evaluated by multidisciplinary team on their neurological, medical, neuropsychological, lifestyle profile to reach consensus diagnoses. investigated various types SCD, including single‐question, general memory decline, specific based list questions three naming, orientation, calculation decline. Results In...
Background: Subjective cognitive decline (SCD) refers to self-evaluations of impairment in functions the absence objective deficits. Frailty is a multidimensional syndrome that results increased vulnerability. Both terms are associated with and incidence dementia. The aim this study was explore potential associations between SCD frailty elderly individuals.Methods: In cross-sectional study, we included 1454 participants aged 65 older from Hellenic Longitudinal Investigation Aging Diet...
In Greece vector borne diseases (VBD) and foremost West Nile virus (WNV) pose an important threat to public health the tourist industry, primary sector of contribution national economy. The island Crete, is one Greece's major destinations receiving annually over 5 million tourists making regional VBD control both a economic priority.
OnabotulinumtoxinA (BoNTA) demonstrated a positive benefit-risk in chronic migraine (CM) patients PREEMPT I and II phase III trials many subsequent real-world studies. We herein aimed at evaluating the adherence to repeated BoNTA over period of five years, while secondary objectives included assessment its long-term safety/efficacy patients' satisfaction treatment.We studied 56 CM who had successfully received consequent cycles years. Adherence was calculated as percentage actively choosing...
Familial Mediterranean fever (FMF) is an autosomal recessive disease characterized by recurrent, acute, and self-limiting attacks of fever. Mutations in MEFV gene encoding pyrin account for FMF, but the high number heterozygote patients with typical symptoms has driven a alternative aetiopathogenic hypotheses. The was knocked down human myelomonocytic cells that express endogenous to identify deregulated microRNAs (miRNAs). Microarray analyses revealed 29 significantly differentially...
Objectives: Recently a declining trend in dementia incidence rates has been reported high-income countries. We investigated representative sample of the Greek population age group 65 years and above. Methods: This research is part Hellenic Epidemiological Longitudinal Investigation Aging Diet (HELIAD). The cohort consisted 1072 participants who were reevaluated after mean period 3.09 years. Results: rate was 19.0 cases per 1000 person-years (age-standardized sex-standardized incidence:...
Multiple sclerosis (MS) results in an extensive use of the health care system, even within first years diagnosis. The effectiveness and accessibility system may affect patients' quality life. aim present study was to evaluate resource MS patients under interferon beta-1b (EXTAVIA) treatment Greece, demographic or clinical factors that this also patient satisfaction with system. Structured interviews were conducted for data collection. In total, 204 (74.02% females, mean age (SD) 43.58...
Background: To investigate the efficacy and safety of supplementation with a fixed combination magnesium, vitamin B2, feverfew, andrographis paniculata coenzyme Q10 in episodic migraine (EM) prevention. Methods: A pilot, single-arm, open-label study was conducted. After one-month baseline period, above-described introduced 113 EM Greek patients, who were prospectively followed-up for three months. The primary endpoint change monthly days between period (BSL) third month (T3). Secondary...
We aimed to prospectively assess the role of needle length in improving tolerability/safety profile OnabotulinumtoxinA (BoNTA) for chronic migraine (CM) prophylaxis, with a specific focus on neck pain, based patients' body habitus and other variables.BoNTA was administered quarterly two consecutive cycles, using standard 0.5-inch 27 G at all pre-defined PREEMPT injection sites, except left-hand side trapezius paraspinal muscles, which were injected longer needles 1-inch 23 first second...
We aimed to provide insights on the role of circadian time administration in influencing efficacy and tolerability/safety profile OnabotulinumtoxinA (BoNTA) for chronic migraine (CM) prophylaxis. Methods: retrospectively reviewed medical files BoNTA-naïve patients with CM who completed three consecutive cycles treatment, according standard PREEMPT paradigm. Participants were classified those scheduled be treated morning hours from 8:00 12:00 (AM) or afternoon 13:00 18:00 (PM). then assessed...
Abstract Very few data are available regarding the association of adherence to Mediterranean Diet (MeDi) with Subjective Cognitive Decline (SCD) evolution over time. A cohort 939 cognitively normal individuals reporting self-experienced, persistent cognitive decline not attributed neurological, psychiatric or medical disorders from Hellenic Epidemiological Longitudinal Investigation Aging and (HELIAD study) was followed-up for a mean period 3·10 years. We defined our SCD score as number...
The primary objective of this multicentre, prospective, observational study was to assess whether there is improvement in the patients' quality life under treatment with rivastigmine transdermal patch, as it evaluated both by patients and their caregivers. Compliance safety were secondary endpoints.In total, 1509 mild moderate Alzheimer's disease, already treated patch 4.6 or 9.5 mg/24 h, enrolled within a 2.4-month period prospectively followed up for 2 months on an outpatient basis....