Ján Tkáč

ORCID: 0000-0002-0765-7262
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About
Contact & Profiles
Research Areas
  • Advanced biosensing and bioanalysis techniques
  • Glycosylation and Glycoproteins Research
  • Electrochemical sensors and biosensors
  • Monoclonal and Polyclonal Antibodies Research
  • Electrochemical Analysis and Applications
  • Analytical Chemistry and Sensors
  • MXene and MAX Phase Materials
  • Biosensors and Analytical Detection
  • Advanced Biosensing Techniques and Applications
  • Microbial Metabolic Engineering and Bioproduction
  • Carbohydrate Chemistry and Synthesis
  • Mass Spectrometry Techniques and Applications
  • Molecular Junctions and Nanostructures
  • Polymer Surface Interaction Studies
  • Microbial Fuel Cells and Bioremediation
  • 2D Materials and Applications
  • Immunotherapy and Immune Responses
  • Microbial metabolism and enzyme function
  • bioluminescence and chemiluminescence research
  • Galectins and Cancer Biology
  • Conducting polymers and applications
  • Microfluidic and Capillary Electrophoresis Applications
  • Advanced Memory and Neural Computing
  • Extracellular vesicles in disease
  • Gold and Silver Nanoparticles Synthesis and Applications

Slovak Academy of Sciences
2016-2025

Institute of Chemistry of the Slovak Academy of Sciences
2015-2024

Slovak University of Technology in Bratislava
1999-2021

University of Rome Tor Vergata
2021

Wrocław University of Science and Technology
2021

AGH University of Krakow
2021

Technical University of Košice
2010-2015

University of Oxford
2007-2010

The University of Queensland
2010

St James's University Hospital
2009

Abstract Impedimetric affinity biosensors are, without any doubt, among the most sensitive analytical devices available, offering low limits of detection and wide linear response ranges. There however, only a few papers detailing application impedimetric for analysis clinically relevant samples with due clinical performance. The fact that these have not found their way to commercial or use date might be surprising, since an electrochemical assay platform based on portable potentiostats is...

10.1002/celc.201800848 article EN ChemElectroChem 2018-09-01

10.1016/j.electacta.2014.05.119 article EN Electrochimica Acta 2014-06-02

Two-dimensional layered nanomaterial Ti3C2TX (a member of the MXene family) was used to immobilise enzyme sarcosine oxidase fabricate a nanostructured biosensor. The device applied for detection sarcosine, potential prostate cancer biomarker, in urine first time. morphology and structures have been characterised by atomic force microscopy (AFM) scanning electron (SEM). Electrochemical measurements, SEM AFM analysis revealed that interfaced with chitosan is an excellent support immobilisation...

10.3390/pr8050580 article EN Processes 2020-05-13

Ultrasensitive impedimetric lectin biosensors recognizing different glycan entities on serum glycoproteins were constructed. Lectins immobilized a novel mixed self-assembled monolayer containing 11-mercaptoundecanoic acid for covalent immobilization of lectins and betaine terminated thiol to resist nonspecific interactions. Construction based Concanavalin A (Con A), Sambucus nigra agglutinin type I (SNA), Ricinus communis (RCA) polycrystalline gold electrodes was optimized characterized with...

10.1021/ac401281t article EN Analytical Chemistry 2013-07-01

In recent decades, the design and construction of smart materials capable switching into a polyzwitterionic state by an external trigger have been intensively pursued. Polyzwitterionic states unique antifouling surface properties triggers, such as pH, light, ions, electric field CO2, cause significant changes in with regard to overall charge, ionic strength wettability. This survey highlights current progress irreversible well reversible process involving moieties, which can, turn, be...

10.3390/polym7111518 article EN Polymers 2015-11-20

In this work, the spontaneous and NaBH 4 -induced reduction of chloroplatinic acid on surface Ti 3 C 2 T X MXene was investigated to synthesize a hybrid PtNP-decorated nanomaterial (MX-Pt) with potential as hydrogen evolution (HER) or oxygen reaction (ORR) catalyst properties.The initial Pt concentration, time presence additional reducing agents were varied, as-synthesized nanocomposites characterized thoroughly by XRD, EDX, SEM XPS analysis electrochemical methods.Composites containing 14...

10.1149/2.0991902jes article EN Journal of The Electrochemical Society 2019-01-01

This review presents the basic characteristics of MXene, a novel 2D nanomaterial with many outstanding properties applicable to electrochemical sensing and biosensing. The second part deals impedance spectroscopy (EIS) its beneficial features ultrasensitive label-free main recent advances in integration MXene design interfaces. EIS was used evaluate effect anodic potential on preparation route for characterization grafted polymers. It also included application as transducing tool antibody-...

10.3390/chemosensors8040127 article EN cc-by Chemosensors 2020-12-07
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