A5105517281- Particle physics theoretical and experimental studies
- High-Energy Particle Collisions Research
- Particle Detector Development and Performance
- Quantum Chromodynamics and Particle Interactions
- Dark Matter and Cosmic Phenomena
- Computational Physics and Python Applications
- Neutrino Physics Research
- Cosmology and Gravitation Theories
- Radiation Detection and Scintillator Technologies
- Distributed and Parallel Computing Systems
- Medical Imaging Techniques and Applications
- Neuroinflammation and Neurodegeneration Mechanisms
- Astrophysics and Cosmic Phenomena
- Alzheimer's disease research and treatments
- Black Holes and Theoretical Physics
- Phytochemicals and Antioxidant Activities
- Atomic and Subatomic Physics Research
- Fermentation and Sensory Analysis
- Circadian rhythm and melatonin
- Food Quality and Safety Studies
- Atomic and Molecular Physics
- Robot Manipulation and Learning
- Autophagy in Disease and Therapy
- Big Data Technologies and Applications
- Machine Fault Diagnosis Techniques
Columbia University
2021-2025
Huazhong University of Science and Technology
2022-2025
Tel Aviv University
2021-2024
Union Hospital
2022-2024
Union Hospital
2024
A. Alikhanyan National Laboratory
2024
SR Research (Canada)
2024
Federación Española de Enfermedades Raras
2024
Atlas Scientific (United States)
2024
The University of Adelaide
2022-2023
Circadian disturbance is a common nonmotor complaint in Parkinson's disease (PD). The molecular basis underlying circadian rhythm PD poorly understood. Neuroinflammation has been identified as key contributor to pathology. In this study, we explored the potential link between core clock molecule Rev-erbα and microglia-mediated NLR family pyrin domain-containing 3 (NLRP3) inflammasome pathogenesis.We first examined diurnal rhythms changes inflammatory cytokines expression SN of MPTP-induced...
Accurate travel time prediction is essential for improving urban mobility, traffic management, and ride-hailing services. Traditional link- path-based models face limitations due to data sparsity, segmentation errors, computational inefficiencies. This study introduces an origin–destination (OD)-based framework leveraging high-resolution trajectory data. Unlike previous works, our approach systematically integrates spatiotemporal, quantified weather metrics driver behavior clustering enhance...
Circadian rhythms are involved in the regulation of many aspects body, including cell function, physical activity and disease. disturbance often predates typical symptoms neurodegenerative diseases is not only a non-motor symptom, but also one causes their occurrence progression. Glial cells possess circadian clocks that regulate function to maintain brain development homeostasis. Emerging evidence suggests microglial clock physiological processes, such as cytokine release, phagocytosis,...
The intricate functional interactions between mitochondria and lysosomes play a pivotal role in maintaining cellular homeostasis proper functions. This dynamic interplay involves the exchange of molecules signaling, impacting metabolism, mitophagy, organellar dynamics, responses to stress. Dysregulation these processes has been implicated various neurodegenerative diseases. Additionally, mitochondrial-lysosomal crosstalk regulates exosome release neurons glial cells. Under stress conditions,...
Abstract Introduction Microglia are the main phagocytes in brain and can induce neuroinflammation. Moreover, they critical to alpha‐synuclein (α‐syn) aggregation propagation. Plasma exosomes derived from patients diagnosed with Parkinson's disease (PD‐exo) reportedly evoked α‐syn inflammation microglia. In turn, microglia internalized released exosomal α‐syn, enhancing However, specific mechanism through which PD‐exo influences degradation remains unknown. Methods Exosomes were extracted...
The decay properties of the short-lived isotope $^{220}\mathrm{Pa}$ were re-investigated via reaction $^{40}\mathrm{Ar}+^{187}\mathrm{Re}$ at gas-filled recoil separator Spectrometer for Heavy Atoms and Nuclear Structure. digital pulse processing technique was applied to resolve evaporation residues--$\ensuremath{\alpha}$ ($\mathrm{ER}\ensuremath{-}\ensuremath{\alpha}$) pileup signals in $^{220}\mathrm{Pa}$. $\ensuremath{\alpha}$-decay chain leading well-known $^{216}\mathrm{Ac}$ established...
The paper employs deep learning to classify breast cancer histopathological image into benign and malignant categories. Inception v1 convolutional neural network is mainly adopted. Spatial Pyramid Pooling special global average pooling are added the ensure that images can be imported in original aspect ratio format. experimental results show performs well classification, Global Average effect slightly better than Pooling.
Sleep is involved in regulating many aspects of the body, including cell function, physical activity, and disease. Neurodegenerative diseases are often preceded by sleep disturbance. This disturbance not just a non-motor symptom but also an important risk factor for developing It now understood that glymphatic system plays physiological functions human body: maintaining balance interstitial fluid clearing waste products from metabolism or death brain. Glymphatic dysfunction contributes to...
Visual–tactile fusion information plays a crucial role in robotic object classification. The module existing visual–tactile models directly splices visual and tactile features at the feature layer; however, for different objects, contributions of to classification are different. Moreover, direct concatenation may ignore that more beneficial will also increase computational costs reduce model efficiency. To utilize effectively further improve efficiency accuracy classification, we propose...
<title>Abstract</title> <bold>Objective</bold> The aim of this study was to explore the risk factors influencing adverse outcomes in patients with acute ischemic stroke (AIS)within one year and establish a linear prediction model based on them. <bold>Methods</bold> We conducted retrospective analysis 600 AIS treated at our hospital from January 2019 June 2023. They were divided into an observation group (n=100, prognosis) control (n=500, good occurrence events within year. Statistical...
Gathering behavior. are commonly observed in nature. Animal migration, bacterial movement, and the beating of heart pulse, exhibit collective behaviors all certain aggregation behaviors. In 2007, Cucker Smale proposed Cucker-Smale model, which can effectively characterize 2017, Ha et al improved considered effect temperature on phenomena. This model is generally referred to as thermodynamic Cucker- (TCS for short) . Specifically, this article explores asymptotic stability with a specific...
Exposure to pyrethroids, a significant class of the most widely used agricultural chemicals, has been associated with an increased risk Parkinson’s disease (PD). However, underlying mechanisms pyrethroid-induced Parkinsonism remain unknown. In this study, we focused on 3-phenoxybenzoic acid (3-PBA), common and prominent metabolite pyrethroids produced via hydrolysis by carboxylesterases (CEs) in mammals. We performed liquid chromatography-tandem mass spectrometry (LC-MS/MS) analysis observed...