A5000844251- Pharmaceutical studies and practices
- Heart Failure Treatment and Management
- Cardiac pacing and defibrillation studies
- Preterm Birth and Chorioamnionitis
- Olfactory and Sensory Function Studies
- Antibiotics Pharmacokinetics and Efficacy
- Herbal Medicine Research Studies
- Maternal and fetal healthcare
- Pharmaceutical Economics and Policy
- Health Systems, Economic Evaluations, Quality of Life
- Prenatal Screening and Diagnostics
- Cancer Genomics and Diagnostics
- Fetal and Pediatric Neurological Disorders
- Drug Solubulity and Delivery Systems
- Delphi Technique in Research
- Ginseng Biological Effects and Applications
- Adult and Continuing Education Topics
- Exercise and Physiological Responses
- Sensory Analysis and Statistical Methods
- Higher Education Learning Practices
- Medication Adherence and Compliance
- Biochemical Analysis and Sensing Techniques
- Color perception and design
- Maternal and Neonatal Healthcare
- Ectopic Pregnancy Diagnosis and Management
The University of Sydney
2023
Ethicare (Germany)
2019-2020
University of Calgary
2020
University College Cork
2016-2019
Access to Wholistic and Productive Living Institute
2019
Munster Technological University
2019
Cork University Hospital
2016
Dalhousie University
2008-2015
Izaak Walton Killam Health Centre
2008
University of Alberta
2008
Preterm premature rupture of membranes (PPROM) complicates 1 % all pregnancies and occurs in one third preterm deliveries. Midtrimester PPROM is often followed by spontaneous miscarriage elective termination ongoing offered many countries. The aim this retrospective descriptive cohort study was to investigate the natural history midtrimester a jurisdiction where pregnancy absence maternal compromise unavailable. Cases diagnosed between 14 23 + 6 weeks' gestation during April 2007 June 2012...
Treatment of paediatric heart failure is based on paradigms extensively tested in the adult population assuming similar underlying pathophysiological mechanisms. Angiotensin converting enzyme inhibitors (ACEI) like enalapril are one cornerstones treatment and commonly used off-label children. Dose recommendations have been extrapolated from experience, but relationship between dose pharmacokinetics (PK) (young) children insufficiently studied. Furthermore, appropriate formulations lacking....
Ginseng is a popular herbal remedy that reputed to increase resistance stress and improve immune function. Regular exercise results in acute physiologic affects the response. This study was conducted investigate effects of daily consumption standardized ginsenoside-containing North American ginseng (Panax quinquefolius) extract on function before, during, after moderate-exercise protocol healthy sedentary men. Ten males were randomized receive either (1125 mg·d –1 ) or placebo for 35 days....
It is well established that treatment regime compliance linked to the acceptability of a pharmaceutical formulation, and hence also therapeutic outcomes. To end, must be assessed during development all products especially for those intended paediatric patients. Although multifaceted concept, poor sensory characteristics often contribute patient acceptability. In particular, taste cited as major reason many patients, children, refuse take their medicine. thus important understand and, far...
Objective To characterise heart failure (HF) maintenance pharmacotherapy for children across Europe and investigate how angiotensin-converting enzyme inhibitors (ACE-I) are used in this setting. Methods A Europe-wide web-based survey was conducted between January May 2015 among European paediatricians dedicated to cardiology. Results Out of 200-eligible, 100 physicians representing hospitals 27 countries participated. All participants reported prescribing ACE-I treat dilated...
Excipients are often the major component of formulation that critically affect dosage form, manufacturing process, product performance, stability and safety. They exert different roles functions in a form. Selecting excipients with appropriate safety tolerability is hurdle paediatric development. The suitability particular excipient will be dependent on context its use regard to age range, acute versus chronic use, clinical benefit-risk disease, active excipient. Scientists encouraged apply...
It is necessary to use a scientifically sound process for excipient risk evaluation, selection, and management in order develop paediatric medicinal products that are both safe effective. The "Paediatric Excipient Risk Assessment (PERA)" framework, which proposes comprehensive approach by considering all relevant factors related patient, dosage form, attributes, was developed published as part 1 of this paper series, enable the rational selection excipients products. This article Part 2...
Little evidence exists to support pharmacotherapeutic strategies for heart failure management in paediatrics. A recent Europe-wide survey suggests that this translates into substantial variability clinical practice.To conduct a formal discussion among an expert group of paediatric cardiology physicians on controversial aspects regarding the pharmacotherapy children failure, facilitate consensus, and highlight areas agreement disagreement.A two-round modified Delphi process was conducted...
Background ACE-inhibitors are first choice treatment for adult and paediatric patients with heart failure. Since there no systematic data on pharmacokinetics safety in the young failure population, EU funded a drug development program 1 to fill those gaps ACE-inhibitor enalapril. An age appropriate formulation was also required. Methods A patient cohort recruited fulfil investigation plan (PIP) requirements. The PIP required total of 85 evaluable from birth less than 12 years subset 25 due...
This presentation will highlight an Adult Education initiative delivered in Cork City through collaboration between members of the Learning Neighbourhoods Project. It outline outreach provision Certificate Mental Health Community and how this is non-traditional settings to achieve successful collaboration, support accessible participation lifelong learning build capacity communities. The process creating a space transformative be outlined as well programme serves enable students address...