A5100768645- Tracheal and airway disorders
- Gastric Cancer Management and Outcomes
- Pancreatic and Hepatic Oncology Research
- Cholangiocarcinoma and Gallbladder Cancer Studies
- Lung Cancer Treatments and Mutations
- Cancer, Hypoxia, and Metabolism
- Radiomics and Machine Learning in Medical Imaging
- Growth Hormone and Insulin-like Growth Factors
- Head and Neck Cancer Studies
- Liver Disease Diagnosis and Treatment
- Cancer-related Molecular Pathways
- Metastasis and carcinoma case studies
- Esophageal and GI Pathology
- Cancer Diagnosis and Treatment
- Inflammatory mediators and NSAID effects
- Dysphagia Assessment and Management
- Lung Cancer Research Studies
- Bariatric Surgery and Outcomes
- Enhanced Recovery After Surgery
- Gallbladder and Bile Duct Disorders
- Organ Transplantation Techniques and Outcomes
- Cancer Genomics and Diagnostics
- Monoclonal and Polyclonal Antibodies Research
- Hepatocellular Carcinoma Treatment and Prognosis
- Oral health in cancer treatment
Guangxi Medical University
2016-2025
First Affiliated Hospital of GuangXi Medical University
2016-2025
Nanjing University of Chinese Medicine
2024
Qingdao University
2021-2024
Affiliated Hospital of Qingdao University
2021-2024
The Fourth People's Hospital of Ningxia Hui Autonomous Region
2024
Air Force Medical University
2006-2021
First Affiliated Hospital of Xi'an Jiaotong University
2014-2021
Xijing Hospital
2019-2021
Yuhuangding Hospital
2021
INTRODUCTION: Prostate-specific membrane antigen (PSMA) was originally found to be specifically expressed in normal prostate, and its expression upregulated almost all stages of prostate cancer. In recent years, PSMA also tumor-associated vasculature many nonprostatic solid tumors. However, the pattern hepatocellular carcinoma (HCC) is not well studied. METHODS: this study, we examined 103 HCC tissues using immunohistochemical staining analyzed association between other clinicopathological...
Abstract Background and objective Bronchiectasis is a chronic respiratory disease with diverse causes that may differ in clinical features thus treatment options. However, few large‐scale studies on the aetiology of bronchiectasis are currently available. This study aims to determine C hinese H an population. Methods prospective enrolled adult patients diagnosed as confirmed by high‐resolution computed tomography at five general hospitals Shandong from J anuary 2010 A ugust 2014. Causes were...
In this study, we examined the characteristics and aimed to increase knowledge of clinical features leptomeningeal metastasis (LM). The data, including initial diagnosis treatment primary tumor, manifestations, neuroimaging findings, cerebrospinal fluid (CSF) examination, were analyzed. For patients with adenocarcinoma/breast cancer, incidence cranial lesions nerve paralysis was obviously higher than small cell lung cancer. Whereas, involvement intravertebral canal lower that Patients cancer...
Background Recent research showed that probiotics treatment may reduce insulin resistance, regulate lipid metabolism, raise liver enzyme levels, and ameliorate inflammation in individuals with metabolic associated fatty disease (MAFLD). However, the possible effects of probiotic use on progression hepatic steatosis (HS) have not been identified. The purpose this study was to investigate a large population database. Methods cross-sectional conducted among adults complete data yogurt...
Non-alcoholic fatty liver disease (NAFLD) is a globally widespread disease. Recent investigations have highlighted close association between immunity and NAFLD, but the causality them has not been thoroughly examined. A total of 731 immunological traits NAFLD cohorts were derived from genome-wide study summary data, single nucleotide polymorphisms significantly associated with immune identified as instrumental variables. Moreover, phenotypes include absolute cell counts, median fluorescence...
Background: Inflammatory bowel disease (IBD) is a persistent, non-specific inflammation affecting the intestines. Psoriasis long-lasting inflammatory disorder of skin. There comorbidity correlation between IBD and psoriasis, but specific pathogenesis unclear. Materials methods: In this study, we analyzed datasets sourced from Gene Expression Omnibus (GEO) database, identified shared genes psoriasis through differential expression analysis weighted gene co-expression network (WGCNA). Then...
Abstract Background and Aim: The activation of Rho proteins has been shown to lead loss polarity in cancer cells, as well reorganization the cytoskeleton facilitation cell motility, possibly resulting their malignant potential. clinicopathological significance RhoA, however, is not yet known case hepatocellular carcinoma (HCC). This study evaluated correlation RhoA levels with HCC. Methods: intratumor expression level was determined compared that adjacent non‐cancerous hepatic tissue using...
Patients with endotracheal intubation or tracheostomy are subject to benign tracheal stenosis (TS), for which current therapies unsatisfactory. We conducted a preliminary investigation of drugs and drug combinations the prevention treatment TS in rabbit model.Fifty-four rabbits were apportioned into nine groups according treatment: sham-operated control; untreated model; amikacin; budesonide; erythromycin; penicillin; amikacin + erythromycin penicillin budesonide. was induced by abrasion...
Background: Pancreatic ductal adenocarcinoma (PDAC) is one of the most aggressive human malignancies.The metabolomic approaches are developed to discover novel biomarkers PDAC.Methods: 550 preoperative, postoperative PDAC and normal controls (NCs) serums were employed characterize metabolic alterations in training validation sets by LC-MS. Results:The results PLS-DA analysis indicated that three groups could be distinguished clearly post-PDAC group adjacent a as compared with pre-PDAC...
This study aimed to analyze the landscape of publications on bariatric metabolic surgery through machine learning and help experts scholars from various disciplines better understand surgery's hot topics trends.In January 2021, indexed in PubMed under Medical Subject Headings (MeSH) term 'Bariatric Surgery' 1946 2020 were downloaded. Python was used extract publication dates, abstracts, research metadata for bibliometric evaluation. Descriptive statistical analysis, social network analysis...
Aim: To evaluate serum soluble fragments of cytokeratin 19 (i.e., CYFRA21-1) as a tumor marker for patients with squamous cell lung carcinoma (SCLC) and oropharynx (OSCC). Patients & methods: A total 152 SCLC OSCC, 84 control were included in the study. CYFRA21-1 concentration was measured using electrochemiluminescence immunoassays. Results: As disease stages increased, concentrations sensitivity increased significantly OSCC. significant difference between pretherapeutic group recurrence...
Objective: To compare perioperative, functional, and oncologic outcomes between robot-assisted partial nephrectomy (RAPN) laparoscopic (LPN) for renal hilar tumors. Methods: We retrospectively reviewed patients who underwent minimally invasive tumors at our institution January 2014 August 2018. The entire cohort was divided into two groups according to surgical approach: RAPN LPN group. Perioperative, of the were collected compared. Results: A total 116 with identified, including 52 64 LPN,...
Talaromyces marneffei (formerly known as Penicillium ) is a dimorphic fungus endemic in south and southeast Asia. It not only commonly found human immunodeficiency virus (HIV)–infected patients, but also among HIV-negative immunocompromised patients. The infection caused by this pathogen can disseminate hematogenously to other locations. Herein, we report for the first time two cases complicated with rare disease or involving site: case, T. was Langerhans cell histiocytosis, whereas second...
Renal cell carcinoma (RCC) is characterized by significant vascularization and immunogenicity, which contributes to drug resistance immune escape. CD248, a pericytes marker in tumor vasculature, might help explain microenvironment (TME) remodeling serve as novel therapeutic target.Transcriptome data clinical information of RCC patients were obtained from The Cancer Genome Atlas (TCGA) database. ESTIMATE population (MCP)-counter algorithms adopted calculate stromal contents. prognostic value...
The lemur tyrosine kinase-3 (LMTK3) has been reported to be involved in tumor progression. aim of this study was determine the diagnostic and prognostic significances preoperative serum LMTK3 non-small cell lung cancer (NSCLC) patients. Sera were collected from 100 healthy volunteers (HV), 280 benign diseases (BLD) patients, 524 NSCLC patients prior operation. level detected by ELISA. We found that markedly elevated compared with controls. receiver operating characteristic (ROC) curve...
Forkhead box P3 (FOXP3) is the essential transcription factor for function of regulatory T-cell (Treg). However, gene mutation FOXP3 in patients with chronic obstructive pulmonary disease (COPD) at different stages has not been reported. We aim to investigate four single nucleotide polymorphisms (SNPs) and mRNA expression smokers normal lung COPD stages. SNPs were assessed nonsmokers (N), (S), Global Initiative Chronic Obstructive Lung Disease (GOLD) 1 or 2 grade (COPD 1–2), GOLD 3 4 3–4)....
The aim of the present study was to investigate diagnostic value glypican-3 (GPC3), arginase-1 (Arg-1), and hepatocyte paraffin antigen 1 (HepPar-1) in differentiating hepatocellular carcinoma (HCC) from intrahepatic cholangiocarcinoma (ICC).
Background Malignant pleural effusion is a common complication of non‐small cell lung cancer (NSCLC); however, treatment options remain limited. This study evaluated the safety and efficacy sequential intrapleural therapy with lobaplatin erythromycin for NSCLC‐mediated malignant effusion. Methods Fifty‐six patients NSCLC complicated were recruited prospective single‐arm from December 2014 to 2016; one patient dropped out. In addition conventional systemic chemotherapy, intrapleurally...