A5010639580- Microbial Metabolic Engineering and Bioproduction
- Enzyme Structure and Function
- Bacterial Genetics and Biotechnology
- Liver Disease Diagnosis and Treatment
- Protein purification and stability
- Mitochondrial Function and Pathology
- Bariatric Surgery and Outcomes
- Gas Sensing Nanomaterials and Sensors
- Supercapacitor Materials and Fabrication
- Advanced Chemical Sensor Technologies
- Virus-based gene therapy research
- Synthesis and properties of polymers
- Polymer Nanocomposites and Properties
- Gut microbiota and health
- Gene Regulatory Network Analysis
- Advanced Photocatalysis Techniques
- Glycosylation and Glycoproteins Research
- Conducting polymers and applications
- Ferroptosis and cancer prognosis
- Cancer Immunotherapy and Biomarkers
- Analytical Chemistry and Sensors
- Polymer crystallization and properties
- Biofuel production and bioconversion
- Chronic Myeloid Leukemia Treatments
- Probiotics and Fermented Foods
Intelligent Health (United Kingdom)
2025
Dalian Medical University
2020-2024
Qingdao University
2022-2024
Affiliated Hospital of Qingdao University
2022-2024
First Affiliated Hospital of Kunming Medical University
2021-2024
Kunming Medical University
2021-2024
Henan Institute of Science and Technology
2024
Shandong University of Technology
2024
WuXi AppTec (China)
2024
Henan University of Engineering
2024
As a novel inflammatory marker, Systemic Immune-Inflammation Index (SII) has not been studied with hepatic steatosis. The aim of this study was to investigate the possible relationship between SII and steatosis.In cross-sectional investigation, adults having complete information on SII, steatosis, bariatric surgery from 2015-2018 National Health Nutrition Examination Survey (NHANES) were included. Hepatic steatosis evaluated heaptic index (HSI). platelet count × neutrophil count/lymphocyte...
The proteome reflects the available cellular machinery to deal with nutrients and environmental challenges. most common E. coli strain BL21 growing in different, commonly employed media was evaluated using a detailed quantitative analysis.The presence of preformed biomass precursor molecules rich such as Luria Bertani supported rapid growth concomitant acetate formation apparently unbalanced abundances central metabolic pathway enzymes, e.g. high levels lower glycolytic enzymes well pyruvate...
Abstract Background Recombinant protein production can be stressful to the host organism. The extent of stress is determined by specific properties recombinant transcript and protein, rates transcription translation, environmental conditions encountered during process. Results impact T7-promoter controlled genes encoding human basic fibroblast growth factor (hFGF-2) green fluorescent (GFP) as well translation into on E. coli BL21(DE3) were investigated. This was done using expression vectors...
Background Recent research showed that probiotics treatment may reduce insulin resistance, regulate lipid metabolism, raise liver enzyme levels, and ameliorate inflammation in individuals with metabolic associated fatty disease (MAFLD). However, the possible effects of probiotic use on progression hepatic steatosis (HS) have not been identified. The purpose this study was to investigate a large population database. Methods cross-sectional conducted among adults complete data yogurt...
Batch and fed-batch fermentation studies were performed to evaluate the potential of corn steep liquor (CSL)-supplemented acid-hydrolysate soybean meal (AHSM) as an alternative yeast extract (YE) for production L-lactic acid by Lactobacillus casei LA-04-1. The CSL-supplemented AHSM gave outstanding result in supporting from glucose. In exponential fermentation, concentration, yield productivity 162.5 g/L, 89.7% 1.69 g/L per h, respectively, which lower than those with 20 YE (180 90.3%, 2.14...
A covalent bond-induced surface-confined cross-linking is reported to construct one-dimensional coaxial CNT@microporous carbon composite (CNT@micro-C). Octaphenyl polyhedral oligomeric silsesquioxane (Ph-POSS) composed of eight phenyls and a -Si8O12 cage was selected as precursor for microporous carbon. The layer-by-layer phenyl anchored Ph-POSS on the surface CNT; after carbonization etching cages, CNT@micro-C including CNT core shell harvested. thickness can be well tailored from 6.0 20.0...
Abstract A comparison of the metabolic response Escherichia coli BL21 (DE3) towards production human basic fibroblast growth factor (hFGF‐2) or carbon overfeeding revealed similarities which point to constraints in anabolic pathways. Contrary expectations, neither energy generation (e.g., ATP) nor provision precursor molecules for nucleotides uracil) and amino acids pyruvate, glutamate) limit host cell plasmid‐encoded functions. Growth inhibition is assumed occur when hampered capacities do...
Osteosarcoma is the most common primary bone malignancy; however, molecular mechanisms of development are not well understood. Progestin and AdipoQ receptors (PAQR3), a protein specifically localized in Golgi apparatus, was recently characterized as new tumor suppressor. Little known about expression function PAQR3 osteosarcoma. Here, we showed that downregulated osteosarcoma tissues compared with adjacent normal regions 80 paired samples. Moreover, lower levels were associated metastasis...
Nitrogen (N) is an essential factor for crop yield. Here, we characterized 605 genes from 25 gene families that form the complex networks of N utilization pathway in Brassica napus . We found unequal distribution between A n - and C -sub-genomes, derived rapa were more retained. Transcriptome analysis indicated activity shifted a spatio-temporal manner B. low (LN) stress RNA-seq seedling leaves roots was generated, which proved most related sensitive to LN stress, thereby forming...
Bariatric surgery is one of the most effective ways to treat morbid obesity, and postoperative nausea vomiting (PONV) common complications after bariatric surgery. At present, mechanism high incidence PONV weight-loss has not been clearly explained, this study aims investigate effect surgical position on in patients undergoing
ABSTRACT Ferroelectric and piezoelectric behavior in odd‐odd polyamide 11,11 are successfully detected for the first time. The maximum coercive field ( E c ) of 90 MV/m, a remnant polarization P r 40 mC/m 2 obtained at room temperature. A strain coefficient d 33 value as high −3.9 pC/N has been found stretched film. structural change samples before after poling is investigated by wide‐angle X‐ray diffraction patterns, differential scanning calorimetry, Fourier transform infrared...
Abstract Long noncoding RNA focally amplified lncRNA on chromosome 1 (FAL1) plays an important role in the development of several human malignancy entities. However, expression and function FAL1 carcinogenesis osteosarcoma remain unknown. In this study, we detected levels tissues cell lines by quantitative real‐time polymerase chain reaction investigated its using vitro assays. Our results showed that was significantly upregulated compared with their normal controls. level positively...
As a member of annexin family proteins, A3 (ANXA3) has 36-kDa and 33-kDa isoforms. ANXA3 plays crucial roles in the tumorigenesis, aggressiveness drug-resistance cancers. However, previous studies mainly focused on role total cancers without distinguishing distinction between two isoforms, cancer remains unclear. Current work aimed to investigate function regulation mechanism hepatocarcinoma. The expressions ANXA3, CRKL, Rac1, c-Myc pAkt were analyzed hepatocarcinoma specimens by Western...
Background: TP53 mutations are the most frequent in hepatocellular carcinoma (HCC) and affect occurrence development of this cancer type. Therefore, it is essential to clarify function mechanism HCC. Methods: We performed a sequence bioinformatic analyses elucidate characteristics downloaded data from The Cancer Genome Atlas database used different R packages for serial analyses, including gene mutation analysis, copy number variation analysis tumor mutational burden microsatellite...