A5089031327- Liver Disease Diagnosis and Treatment
- Hepatitis C virus research
- Cancer-related gene regulation
- HIV-related health complications and treatments
- Liver Diseases and Immunity
- HIV/AIDS drug development and treatment
- Epigenetics and DNA Methylation
- Blood groups and transfusion
- HIV Research and Treatment
- Erythrocyte Function and Pathophysiology
- RNA modifications and cancer
- Neonatal Health and Biochemistry
- Liver Disease and Transplantation
- Blood disorders and treatments
- Hepatitis B Virus Studies
- Diabetes and associated disorders
- Cancer-related molecular mechanisms research
- Hemoglobinopathies and Related Disorders
- Acute Myeloid Leukemia Research
- Platelet Disorders and Treatments
- Blood properties and coagulation
- Acute Lymphoblastic Leukemia research
- Pneumocystis jirovecii pneumonia detection and treatment
- HIV/AIDS Research and Interventions
- SARS-CoV-2 and COVID-19 Research
Medical University of Warsaw
2011-2025
University of Southern Denmark
2021
Odense University Hospital
2021
Greater Poland Cancer Center
2021
Poznan University of Medical Sciences
2020
University of Copenhagen
2017
Rigshospitalet
2017
Centralny Szpital Kliniczny
2013
Adam Mickiewicz University in Poznań
2011
May Institute
2010
People with HIV (PWH) receiving antiretroviral therapy (ART), despite a similar life expectancy, have higher incidence of comorbidities than the general population. This study assessed influence proinflammatory biomarkers and clinical factors on mortality PWH. We included PWH hospitalized from 2009 to 2014 who continued ART until 2023. The baseline lipid profile, CD4+ cell count, platelets, CRP, PCT, TNF-α, VCAM-1, HCV HBV coinfection were evaluated. Multivariable logistic regression was...
Forty-four children with autoimmune haemolytic anaemia (AIHA) are described: 31 had acute, subacute or chronic disease warm autoantibodies and 13 acute cold autoantibodies. The commonest forms were the types these more frequent in young children, while AIHA occurred mainly among at puberty. In about 16% was accompanied by a disorder but over 50% preceded an infection immunization. former gave rise to anaemia, latter associated forms. general prognosis good death never caused per se. worse...
Ascites and spontaneous bacterial peritonitis (SBP) are among the most important complications of decompensated liver cirrhosis. In clinical practice, new inflammation biomarkers needed for early diagnosis SBP, as well-known biomarkers, such C-reactive protein (CRP), procalcitonin (PCT), or peripheral blood white cell (WBC) count, lack required specificity sensitivity. The aim study was to evaluate significance heparin-binding (HBP) in comparison CRP, PCT, WBC, D-dimers SBP.Cross-sectional...
Background . Coagulation disorders in patients with liver cirrhosis are a common clinical problem. Cirrhosis should be considered state of impaired blood clotting or an imbalance the whole coagulation system. Cirrhosis-induced coagulopathy encompasses disturbances both procoagulant and anticoagulant systems. This mechanism may promote development thrombosis portal vein (PVT), which is obstacle to orthotopic transplantation (OLT). We assessed serum ADAMTS-13 levels decompensated cirrhosis,...
Abstract Background Early diagnosis of tuberculosis (TB) is important to reduce transmission, morbidity and mortality in people living with HIV (PLWH). Methods PLWH a TB were enrolled from clinics Eastern Europe followed until 24 months. Delayed was defined as duration symptoms (cough, weight-loss or fever) for ≥ 1 month before diagnosis. Risk factors delayed assessed using multivariable logistic regression. The effect on Kaplan–Meier estimates Cox models. Findings 480/740 patients (64.9%;...
The Human Immunodeficiency Virus and retroviral therapy are both known risk factors for cardiovascular disease. It remains an open question whether HIV or ARV leads to increased arterial inflammation. objective of this study was investigate the changes in endothelial activation by measuring VCAM-1 levels among HIV-infected patients who were not treated with antiretroviral therapy. is a retrospective that included 68 patients, 23 whom never antiretroviral-treated, 15 ART-treated no longer...
Liver biopsy is a well-known method for the diagnosis and evaluation of chronic diffuse liver diseases, especially among patients with "hepatopathy unknown origin".In years 2014-2015 we performed 259 biopsies in 28 (22 females, 6 males, aged 18-65 years, mean: 45 years) an initial origin". The these were revised by two independent pathologists.Histopathological features autoimmune conditions found 11 cases, steatohepatitis with/without Mallory bodies 7, simple steatosis without inflammation...
1. Hunfeld K-P, Hildebrandt A, Gray JS. Babesiosis: Recent insights into an ancient disease. Intern J Parasitol. 2008; 38: 1219–1237. CrossRef Google Scholar
Nuclear paraspeckle assembly transcript 1 (
<b>Background/Aim:</b> The aim of this study was to assess the role serum pigment epithelium-derived factor (PEDF) and matrix metalloproteinase-9 (MMP-9) in progression liver cirrhosis development hepatocellular carcinoma (HCC). <b>Patients Methods:</b> Serum levels PEDF MMP-9 were tested 212 patients with a control group 30 healthy volunteers. HCC diagnosed 45 studied (21%). <b>Results:</b> higher than that (<i>P</i> < 0.001). In alcoholic or mixed (alcoholic viral hepatitis-related)...
A girl, 21 years of age, was admitted to hospital on February 5, 1960, at the Clinic in a state acute general- ized vaccinia.She had been Paediatric age 17 months from August October 20, 1959, where diagnosis leukaemia established by clinical picture, peripheral blood studies and bone marrow examination.After transfusions, administration prednisone (3 mg./ kg./day) 'amethopterin' (methotrexate) (1 -25 mg./24 hours) there remission child discharged home parents instructed continue metho-...
We observed that low concentrations of procalcitonin (PCT) in the early stages bacterial infection among HIV/AIDS patients are not always associated with a good prognosis. Many our developed sepsis despite PCT level <0.5 ng/ml on first days infection. The aim study was to assess whether laboratory standards for correlate their clinical condition. analyzed concentration and other inflammatory markers 40 HIV-infected 52 AIDS enrolled study. control group consisted 37 healthy individuals. In...
Background. With the life expectancy of people living with HIV (PLHIV) rapidly approaching that general population, cardiovascular health in this group is as relevant ever. Adenovirus 36 (Adv36) one few viruses suspected to be a causative factor promoting obesity humans, yet there lack data on infection PLHIV. Methods. PLHIV stable suppressive antiretroviral therapy were included study, assessment anthropometric measures, blood pressure, serum lipid levels, fasting glucose and insulin,...
Most extrahepatic manifestations of the hepatitis C virus (HCV) infection are connected with influence on host's immune system. An important part immunologic disturbances in chronic infections is presence circulating complexes. Standard serologic methods not applicable analysis complexes composition.Detection anticardiolipin antibodies (ACA) cryoglobulins patients HCV before and after dissociation complexes.Sera croglobulins 27 (19 female, 8 male) cryoglobulinemia were tested.ACA searched...
Introduction. Hepatocellular carcinoma (HCC) is a malignancy that primarily affects patients with liver cirrhosis. Early diagnosis crucial for improving patient outcomes. The study aimed to investigate the potential role of glypican-3 (GPC3) serum levels, both alone and in combination alpha-fetoprotein (AFP) gamma-glutamyl transpeptidase (GGT) as diagnostic biomarkers HCC. Methods. included 53 cirrhosis confirmed HCC, who were admitted Department Infectious Diseases, Tropical Diseases...