- Burn Injury Management and Outcomes
- Tryptophan and brain disorders
- Stress Responses and Cortisol
- Hereditary Neurological Disorders
- Traumatic Brain Injury and Neurovascular Disturbances
- Endometriosis Research and Treatment
- Neuroscience and Neuropharmacology Research
- Memory and Neural Mechanisms
- Ovarian cancer diagnosis and treatment
- Ion channel regulation and function
- Assisted Reproductive Technology and Twin Pregnancy
- Lung Cancer Treatments and Mutations
- Zebrafish Biomedical Research Applications
- Mycorrhizal Fungi and Plant Interactions
- Reconstructive Surgery and Microvascular Techniques
- Ovarian function and disorders
- Human-Animal Interaction Studies
- Nerve injury and regeneration
- Neurotransmitter Receptor Influence on Behavior
- Neurological Disease Mechanisms and Treatments
- Intensive Care Unit Cognitive Disorders
- Infant Health and Development
- Gut microbiota and health
- Systemic Sclerosis and Related Diseases
- Vitamin C and Antioxidants Research
Shanghai Jiao Tong University
2022-2023
Zhejiang Cancer Hospital
2023
Chinese Academy of Sciences
2023
Shanghai Mental Health Center
2022-2023
South China University of Technology
2022
Beijing University of Chemical Technology
2022
Hebei University
2022
Institute of Basic Medical Sciences of the Chinese Academy of Medical Sciences
2022
University of Technology
2022
Chongqing Medical and Pharmaceutical College
2018-2019
The neurobiological understanding of obsessive–compulsive disorder (OCD) includes dysregulated frontostriatal circuitry and altered monoamine transmission. Repetitive stereotyped behavior (e.g., grooming), a featured symptom in OCD, has been proposed to be associated with perturbed dopamine (DA) signaling. However, the precise brain circuits participating DA’s control over this behavioral phenotype remain elusive. Here, we identified that DA neurons substantia nigra pars compacta (SNc)...
Abstract Aims This study was designed to investigate the role of NR2B and contribution DNA methylation expression in pathogenesis PND. Methods Eighteen‐month‐old C57BL/6J mice were subjected experimental laparotomy under 1.4% isoflurane anesthesia. Hippocampus‐dependent learning memory evaluated by using Barnes maze contextual fear conditioning tests. The protein mRNA levels western blotting qRT–PCR respectively, gene examined targeted bisulfite sequencing. Long‐term synaptic plasticity...
Two hundred and forty-four ustilaginomycetous yeast or yeast-like strains were isolated from the soil, skin of animals humans plant materials during past 20 years. Among them, 203 represent 39 known species, whereas 41 several novel species based on sequence analyses rDNA genes [18S rDNA, Internal Transcribed Spacer (ITS) regions, 26S D1/D2 domain] three protein ( RPB1, RPB2 , TEF1 ). In this study, one new order, family, four genera, twenty two combinations proposed. They are Franziozymales...
The 9-hole peg test (9-HPT) and 10-meter walk (10-MWT) are commonly used to finger motor function walking ability. aim of this present study was investigate the efficacy these tests for evaluating functional loss in Chinese Charcot-Marie-Tooth (CMT) disease.Thirty-four CMT patients (CMT group) from August 2015 December 2016 were evaluated with 9-HPT, 10-MWT, disease examination score, overall neuropathy limitation scale (ONLS), disability Berg Balance Scale (BBS). Thirty-five age-...
The spleen is critical for immunity. It the largest immune organ and center in peripheral system. While relationship between behavior immunity has been demonstrated physiology diseases, role of not clear. To investigate effects on behaviors, we performed a refined splenectomy procedure C57BL/6J mice an open field test, circadian rhythm elevated plus maze, sucrose preference Barnes maze test. Splenectomy did induce changes general locomotion, rhythms, learning memory, or...
To investigate the impact of an ovarian dermoid cyst or surgery on reserve in patients undergoing vitro fertilization/intracytoplasmic sperm injection (IVF/ICSI). We performed a retrospective cohort study by using records with history who underwent IVF/ICSI between 2009 and 2013. The antral follicle count (AFC) obtained transvaginal ultrasound during controlled hyperstimulation IVF/ICSI, total number basal follicles [i.e., (B-AFC)], dominant greater than 1.4 cm (D-AFC)] were calculated...
Immunotherapy has improved the prognosis of patients with advanced non-small cell lung cancer (NSCLC), but only a small subset achieved clinical benefit.The purpose our study was to integrate multidimensional data using machine learning method predict therapeutic efficacy immune checkpoint inhibitors (ICIs) monotherapy in NSCLC.We retrospectively enrolled 112 stage IIIB-IV NSCLC receiving ICIs monotherapy.The random forest (RF) algorithm used establish prediction models based on five...
Alcohol is one of the most commonly abused drugs, and it impairs diverse functions central nervous system, such as cognition memorization. The dentate gyrus (DG) region hippocampus crucial for spatial memory coding. However, whether alcohol exposure can affect DG neuron activity impair has not been identified. Here, we discovered a key damage. (1) We found repeated overactivated neurons, while this activation was shown in single group. (2) Mice exposed to repeatedly exhibited obvious...
Objective: To analyze the clinical characteristics of early organ injury in elderly patients with severe burns and effects on prognosis patients. Methods: From January 2010 to August 2018, 62 (43 men 19 women, aged from 60 89 years at time admission) who were hospitalized Institute Burn Research First Affiliated Hospital Army Medical University (the Third Military University, hereinafter referred as author's affiliation), meeting inclusion criteria, included (E) group, 124 (86 38 18 59 same...
This article mainly summarized the present situation and development of continuous nursing, which focused on concept importance so as to provide scientific basis for implementation nursing mode in future. Key words: Continuing nursing; Stroke; Research progress
Objective To analyze and summarize the clinical characteristics treatment experience of diabetic foot. Methods The data 43 patients with severe foot treated in department Burns Plastic Surgery Beijing Chaoyang Emergency Medical Center from June 2013 to August 2017 were retrospectively analyzed, divided into 4 groups: amputation group, cutoff toe (toe) group non-amputation group. The age, duration diabetes, hospitalization time, serum albumin concentration, hemoglobin level, white...
Background: Few studies have investigated the differences between fresh D3 embryo transfer (Fre-D3) and cryopreserved-thawed D5 (Fro-D5) cycles in women with an ectopic pregnancy (EP) history. The aim of this study is to evaluate different outcomes fre-D3 Fro-D5 EP Materials Methods: authors performed a retrospective cohort university-based reproductive medicine center including 2,777 Fre-D3 1,120 fro- from 2009 2014. Ectopic delivery rates were measured. Results: incidence after IVF/ICSI...
Abstract Background Spleen is critical for immunity. The spleen the largest immune organ and center in peripheral system. relationship between behavior immunity has been fully reflected physiology diseases, however, role of not clear. Methods To explore potential effects on behavior, here we developed refined splenectomy procedure C57BL/6J mice. And then systemically examined changes general locomotion, circadian rhythms, learning memory, depression/anxiety-related behaviors. Results...