A5102918551- Obesity, Physical Activity, Diet
- Nuclear physics research studies
- Diet and metabolism studies
- Bone health and osteoporosis research
- Body Composition Measurement Techniques
- Quantum Chromodynamics and Particle Interactions
- Diabetes Treatment and Management
- Health and Lifestyle Studies
- Pancreatic function and diabetes
- Cardiovascular Function and Risk Factors
- Children's Physical and Motor Development
- Cardiac Imaging and Diagnostics
- Liver Disease Diagnosis and Treatment
- Sleep and related disorders
- Advanced NMR Techniques and Applications
- Cardiomyopathy and Myosin Studies
- Vitamin D Research Studies
- Trace Elements in Health
- Atherosclerosis and Cardiovascular Diseases
- Alcohol Consumption and Health Effects
- Tissue Engineering and Regenerative Medicine
- Adipokines, Inflammation, and Metabolic Diseases
- Protease and Inhibitor Mechanisms
- Traditional Chinese Medicine Analysis
- Medical Imaging Techniques and Applications
Imperial College London
2024-2025
Union Hospital
2024
Huazhong University of Science and Technology
2024
Leibniz Institute for Prevention Research and Epidemiology - BIPS
2019-2024
First Affiliated Hospital of Jiangxi Medical College
2023-2024
Wuhan Union Hospital
2024
Jiangxi Provincial People's Hospital
2021-2023
Tianjin Central Hospital of Gynecology Obstetrics
2022
Nanchang University
2021
Peking University
1983-2020
Aims Mesenchymal stem cells (MSCs), rare bone marrow-derived cell precursors of non-haematopoietic tissues, have shown promise in potentially repairing infarcted myocardium. These and similar types are being tested clinically, but understanding delivery subsequent biodistribution is lacking. This study was designed to quantitatively compare MSC engraftment rates after intravenous (IV), intracoronary (IC), or endocardial (EC) a porcine myocardial infarction (MI) model.
Isolated left ventricular noncompaction (LVNC) results from excessive trabeculation and impaired myocardial compaction during heart development. The extracellular matrix (ECM) that separates endocardium myocardium plays a critical but poorly understood role in compaction. In an attempt to characterize solute carrier family 39 member 8-null (Slc39a8-null) mice, we discovered homozygous null embryos do not survive embryogenesis exhibit cardiac phenotype similar human LVNC. Slc39a8 encodes...
Behavioral interventions have been shown to be effective in improving dietary behavior and reducing childhood obesity. There is limited evidence on how concurrent changes from intervention studies affect The present study aimed evaluate the mediating effect of behaviors between adiposity indicators. This included 1180 children DECIDE-Children study, which was conducted across three areas China, aiming promote children’s healthy diet physical activity, while also engaging schools families...
Objective— To prospectively evaluate whether the development of fibroatheromas exhibiting features potential instability can be detected and predicted by serial invasive imaging. Methods Results— Multivessel intravascular ultrasound near infrared spectroscopy (NIRS) were performed in diabetic/hypercholesterolemic pigs 3, 6, 9 months after induction. Animals euthanized at histological/immunohistochemical evaluation arteries was (n=304 arterial segments). Intravascular demonstrated, over time,...
Background: A comprehensive approach involving both environmental and individual strategies offers opportunities to strengthen school-based interventions for childhood obesity. Objectives: To evaluate a theory-based intervention implemented within primary schools obesity in China. Methods: 1-year, cluster randomized controlled trial was conducted twelve (7–11 years old) Beijing, Environmental factors were improved the group (6 schools, 930 children) promote knowledge behaviors related energy...
This study aimed to investigate the association between D-dimer and cardiovascular diseases outcomes in patients with type 2 diabetes.This is a single-center retrospective cohort which was performed population who had health examinations 2010 2015 Jiangxi Provincial People's Hospital. All adult were diagnosed diabetes screened. The events defined as all-cause mortality, new incidence (acute myocardial infarction, unstable angina, stroke), or mortality.The median age 59.6 years; 50.1% of...
Abstract The current study evaluated the effect of SGLT-2 inhibitor, dapagliflozin, on left ventricular remodeling in patients with type 2 diabetes and HFrEF. 60 were randomized (1:1) to receive dapagliflozin 10 mg once daily, or placebo double blind for 1 year. Patients underwent transthoracic echocardiography doppler evaluation prior initiation at At 1year, adjusted mean difference versus change from baseline LVEF was 2.5% (95% CI: 1.00–4.06, P = 0.002). Adjusted LVED volume − 6.0ml -8.07...
The associations between physical activity (PA), sedentary behaviour (SB) and bone health may be differentially affected by weight status during growth. This study aims to assess the cross-sectional longitudinal PA, SB stiffness index (SI) in European children adolescents, taking into consideration.Calcaneus SI was first measured quantitative ultrasound among aged 2-9 years old 2007/08. It again after 2 IDEFICS 6 I. Family study. A sample of 2008 participants with time spent at sports clubs,...
Abstract The current study evaluated the effect of SGLT-2 inhibitor, empagliflozin, on blood pressure reduction in Chinese elderly hypertension patients with type 2 diabetes and investigated its possible mechanisms. 124 were randomized to receive 25 mg empagliflozin QD, or placebo double blind for 12 weeks. Patients underwent 24-h ABPM. Endothelial function arterial stiffness also measured prior randomization at week 12. At 12, adjusted mean difference versus change from baseline SBP was −...
In this large perspective cohort among European children and adolescents, we observed that daytime napping was positively associated with bone stiffness, while short or long sleep duration combined poor quality less stiffness. Our findings are important for obtaining optimal stiffness in childhood. To examine the cross-sectional longitudinal associations between duration, quality, index (SI) adolescents. Four thousand eight hundred seventy-one aged 2–11 years from IDEFICS study 861 6–15...
Abstract The present study evaluated the effects of dapagliflozin, a SGLT2 inhibitor, or dapagliflozin plus metformin versus monotherapy in patients with metabolic syndrome. This included who admitted Jiangxi Provincial People’s Hospital from January 1, 2017 to December 31, 2019 and were diagnosed A total 248 participants randomly assigned divide into three groups: group; combined group. Dapagliflozin group associated similar improvements components Relative monotherapy, provided greater So...
Abstract Background Food environments have rapidly changed over the past years in China and children more access to unhealthy food convenience stores near schools. Since studies on association between schools obesity had inconsistent results no similar study China, we conducted a Beijing of which will provide scientific evidence for intervention childhood obesity. Methods The included 2201 students at grade 4 37 primary Dongcheng or Miyun district Beijing. environment data was acquired from...
Abstract Objective: We aimed to investigate the associations between school-level characteristics and obesity among Chinese primary school children with consideration of individual-level characteristics. Design: This cross-sectional study was conducted in 2015/2016. School-level were assessed using an interviewer-administered questionnaire, a ‘school-based prevention index’ further developed. Individual-level collected by self-administered questionnaires. Objectively measured height weight...
The relation between the kinematic and dynamic moments of inertia, ${\mathit{scrJ}}^{(1)}$ ${\mathit{scrJ}}^{(2)}$, was analyzed for normally deformed superdeformed rotational bands. According to ab expression spectrum, E(I)=a[ \ensuremath{\surd}1+bI(I+1) -1], ratio R= \ensuremath{\surd}[${\mathit{scrJ}}^{(1)}$${]}^{3}$/${\mathit{scrJ}}^{(2)}$ should be I independent. Extensive analyses bands in rare-earth actinide nuclei show that R's do remain same holds well observed A\ensuremath{\sim}190...
<title>Abstract</title> This study aimed to assess the potential of multiparametric chemical exchange saturation transfer magnetic resonance imaging (CEST MRI) for MCI detection. Twenty-eight patients with and 31 age- gender-matched normal controls (NCs) were enrolled. CEST MRI was performed a gradient spin-echo sequence on 3T scanner. Multi-parametric parameters analyzed, such as amide, amine, amine amide concentration independent assay (AACID), magnetization ratio yielding rex...