A5100421639- Metamaterials and Metasurfaces Applications
- GaN-based semiconductor devices and materials
- Semiconductor Lasers and Optical Devices
- Photonic Crystals and Applications
- Electromagnetic Fields and Biological Effects
- Semiconductor Quantum Structures and Devices
- Color Science and Applications
- Liver Disease Diagnosis and Treatment
- Advanced Fluorescence Microscopy Techniques
- Luminescence and Fluorescent Materials
- Luminescence Properties of Advanced Materials
- Diet and metabolism studies
- Ocular and Laser Science Research
- Physical Unclonable Functions (PUFs) and Hardware Security
- Plasmonic and Surface Plasmon Research
- Perovskite Materials and Applications
- Semiconductor materials and devices
- Laser Material Processing Techniques
- Optical Coatings and Gratings
- Neuroscience and Neural Engineering
- Radiation Detection and Scintillator Technologies
- Lower Extremity Biomechanics and Pathologies
- Molecular Sensors and Ion Detection
- Aluminum toxicity and tolerance in plants and animals
- Optical Polarization and Ellipsometry
ShanghaiTech University
2025
Tianjin Medical University
2011-2024
Nankai University
2023-2024
Yueyang Hospital
2024
Shanghai University of Traditional Chinese Medicine
2024
Tianjin Medical University General Hospital
2023
Tianjin Medical University Cancer Institute and Hospital
2023
National Clinical Research
2023
Shanxi University
2023
Clemson University
2022
Significance How NK cell development diverges from T/B commitment at the common lymphoid progenitor stage is poorly understood. Histone modification near critical gene loci often influences lineage determination. Ezh2 a histone methyltransferase frequently associated with repression. Here we observed that Ezh2-null hematopoietic stem and cells (HSPCs) or HSPCs treated inhibitors gave rise to increased precursors mature progeny display enhanced cytotoxicity against tumor cells. The latter...
The aim of this study is to analyze the effect serum metabolites on diabetic nephropathy (DN) and predict prevalence DN through a machine learning approach. dataset consists 548 patients from April 2018 2019 in Second Affiliated Hospital Dalian Medical University (SAHDMU). We select optimal 38 features least absolute shrinkage selection operator (LASSO) regression model 10-fold cross-validation. compare four algorithms, including extreme gradient boosting (XGB), random forest, decision tree,...
Silicon platforms are widely recognized as an industry standard for photonic integrated circuits. However, conventional tuning mechanisms, such thermo-optic and plasma dispersion effects, impose limitations in advanced applications, quantum computing, where low-loss cryogenic operation critical. Acousto-optic (AO) modulation offers a promising alternative, broadening the scope of silicon photonics. Here, we investigate aluminum nitride (AlN)-silicon hybrid platform to enable AO on...
Although some epidemiological investigations showed a potential association between long-term exposure of extremely low frequency electromagnetic fields (ELF-EMF) and Alzheimer's disease (AD), no reasonable mechanism can explain this association, the related animal experiments are rare. In study, ELF-EMF (50Hz 400µT 60d) combined with D-galactose intraperitoneal (50mg/kg, q.d., 42d) Aβ25–35 hippocampal (5μl/unilateral, bilateral, single-dose) injection was implemented to establish complex...
We have performed coarse grained molecular dynamics simulations (CGMD) to investigate the interactions of generation 7, 5 and 3 (G7, G5 G3) charge-neutral polyamidoamine (PAMAM) dendrimers with a DPPC (dipalmitoylphosphatidylcholine) monolayer at air–water interface (model pulmonary surfactant) during end-expiration process. Our results show that different generations PAMAM influences on monolayer. Generally, G3 little influence monolayer's structure relative properties. While G7 tend induce...
In a previous study, we reported the positive effects of extremely low frequency electromagnetic field (ELF-MF) exposure on Alzheimer's disease (AD) rats; however, underlying mechanism remains unclear. addition, found that Raf-1 kinase inhibitor protein (RKIP) was downregulated by microwave in rat hippocampus. Our hypothesis RKIP-mediated NF-κB pathway signaling is involved effect ELF-MF AD rat. this D-galactose intraperitoneal (50 mg/kg/d for 42 d) and Aβ25-35 hippocampal (5 μL/unilateral,...
Inspired by the light and dark variations observed in natural cloud clusters under sunlight, we propose a three-dimensional (3D) "bionic" fluorescent physically unclonable function (PUF) label. The minimalist preparation process eliminates need for expensive traditional instruments, thus offering new insight into widespread adoption of 3D PUF labels. Eu(CCA)3(H2O)2 powder, which is first to its secondary building unit, was chosen as material. Its morphology preserved resin mimic cloud-like...
Multifunctional β-NaYF<sub>4</sub>:Yb/Er@β-NaYF<sub>4</sub>:Yb/Tm microcrystals with simultaneous white-light emission, temperature-dependent upconversion luminescence multicolor tuning and good temperature sensitivity.
With the novel capabilities of engineering optical wavefront at nanoscale, dielectric metalens has been utilized for fluorescence microscopy imaging system. However, main technical difficulty is how to realize achromatic focusing and light modulation simultaneously by a single-layer in two-photon excitation STED (TPE-STED) endomicroscopy Herein, combining spatial multiplexing technology vortex phase modulation, multitasking vortex-metalens as miniature objective on end fiber was proposed....
With the advantages of completely controlling phase, amplitude, and polarization in subwavelength range, metalenses have drawn intensive attentions high resolution two-photon micro-endoscopic fluorescence imaging system. However, chromatic dispersion severe scattering biological tissue significantly reduce excitation-collection efficiency traditional system based on designed air background. Here, an excitation emission dual-wavelength confocal polarization-insensitive metalens environment...
Low-cost nanocomposite metasurfaces have demonstrated attractive potential to replace the equivalent dielectric for light engineering. However, resonance characteristics of embedded structures in not been further analyzed beyond effective refractive index. Herein, we proposed customizable polarization-selective narrowband meta-filters using ultraviolet-curable (UV) nanocomposites. As an additional degree freedom, near-field effects between highly concentrated doped nanoparticles can enhance...
Abstract With the increasing popularity of internet, it brings convenience to lives while also increases security risks. Physical Unclonable Functions (PUFs) can generate random, unclonable, and unique identifiers using their inherent physical characteristics, which have broad prospects in anti‐counterfeiting. Herein, inspired by irregular tree bark fissures random skin wrinkles found nature, a method for creating complex micro‐wrinkles with unclonable patterns is proposed simply stretching...
We developed a high-index-contrast photonic structure for improving the light extraction efficiency of light-emitting diodes (LEDs) by self-assembly approach. In this approach, two-dimensional grating can be non-lithographically integrated on top virtually any types LEDs with controlled structural parameters and material indices. As proof concept, our designed was implemented GaAs double heterojunction LED. Using numerical electromagnetic simulations, we explored effects (the period, layer...
Multicolor two-photon endomicroscopy has become a highly competitive tool for functional imaging in biomedical researches. However, to make the system miniature and applicable freely behaving animal brain activity, metalenses have received much attention compact systems. For high resolution multicolor maximizing fluorescence collection, there is challenge faced achieve large numerical aperture (NA) focus NIR excitation VIS emission lights of multiple fluorophores same distance simultaneously...
Heat dissipation is an important part of light-emitting diode (LED) filament research and has aroused constant concern. In this paper, we studied the thermal performance flexible LED by numerical simulation through experiment. The heat characteristics spring-like structure were computed finite volume method, it was found that chip junction temperature closely related to pitch bending radius. effect inclination angle lighting discussed because relevant in geometry. results demonstrated...
China is seeing a growing demand for rehabilitation treatments post-stroke upper limb spastic paresis (PSSP-UL). Although acupuncture known to be effective PSSP-UL, there room enhance its efficacy.