A5004281725- Fusion materials and technologies
- Muon and positron interactions and applications
- Cancer Genomics and Diagnostics
- Radiomics and Machine Learning in Medical Imaging
- Pancreatic and Hepatic Oncology Research
- Ion-surface interactions and analysis
- Acupuncture Treatment Research Studies
- Ferroptosis and cancer prognosis
- Metal and Thin Film Mechanics
- Advanced materials and composites
- CAR-T cell therapy research
- Graphene research and applications
- Adsorption and biosorption for pollutant removal
- Nuclear Engineering Thermal-Hydraulics
- Fiber-reinforced polymer composites
- Chemical Synthesis and Characterization
- Nuclear Materials and Properties
- Lung Cancer Research Studies
- Advancements in Transdermal Drug Delivery
- Radioactivity and Radon Measurements
- Radioactive element chemistry and processing
- Oral health in cancer treatment
- Regional Development and Environment
- Nuclear Structure and Function
- Geological and Geophysical Studies
Chinese Academy of Sciences
2013-2025
University of South China
2017-2024
Jilin University
2024
First Affiliated Hospital of University of South China
2017-2024
Nanjing Forestry University
2023
Institute of New Materials
2023
Changsha Central Hospital
2021
Central South University
2021
Xiangya Hospital Central South University
2021
Nantong University
2020
<title>Abstract</title> Therapeutic strategies for peritoneal metastasis in solid tumors are urgently needed the clinic. Programming chimeric antigen receptor macrophages (CAR-Ms) <italic>in situ</italic> offers opportunities an unmet demand. However, potential intracellular domains (ICDs) CAR design and their antitumor mechanisms macrophage empowerment remain to be explored systematically. By developing a targeted mRNA-LNP delivery system macrophages, we have investigated 36 combinations...
Nickel nanoparticles supported on AC (Ni/AC) composites, combining abundant micropores with open metal sites, are rationally designed for adsorbing Rn.
As-annealed Fe–1.5 wt%Cu alloys were deformed by cold rolling. Positron annihilation lifetime spectroscopy (PALS) and Doppler broadening spectra (DBS) used to analyze the microdefects in alloy induced deformation. Cu precipitates formed uniformly after annealing at 1173 K. To investigate effects of on formation migration defects, well-annealed pure Fe samples prepared as a reference. PALS results show that value positron (both long τ2 mean τm) is smaller than during This indicates restrain...
Abstract Bacterial infection stands as one of the biggest threats to public health. In recent years, rise diverse drug‐resistant bacteria has significantly compromised efficacy existing antibiotics in eradicating them, and formation biofilms further weakened treatment effect. this study, a pH‐responsive photodynamic probe, TI, is developed assembled with ROS‐reactive carbon monoxide (CO) donor, then encapsulated within HA‐based microneedle patch, ultimately creating theranostic platform. The...
The coolant temperature feedback coefficient is an important parameter of reactor core power control system. To study the influence on system small PWR, built with nonlinear model and fuzzy theory. Then, uncertainty quantification method parameters established based Latin hypercube sampling Bootstrap method. Finally, under conditions reactivity step perturbation inlet perturbation, analysis for two cases carried out. result shows that controller PID controller, affects system, maximum...
In this paper, we summarized our recent experimental results on Fe-Cu model alloys irradiated by Fe ion. Two kinds of with 0.3%Cu and 0.6%Cu were prepared 2.5 MeV ion at 573 K. Irradiation dose is 0.1 dpa 1.2 for each type alloy respectively. Positron annihilation techniques slow positron beam used to investigate the irradiation induced defects. Results show that S parameters are higher in specimens high dose, but intensity Cu peaks CDB lower. It indicates precipitation atoms formed easily...
Necroptosis is progressively becoming an important focus of research because its role in the pathogenesis cancer and other inflammatory diseases. Our study designed to anticipate survival time kidney renal clear cell carcinoma (KIRC) by constructing a prognostic signature necroptosis-related genes. Clinical information RNA-seq data were acquired from Renal Cell Cancer-European Union (RECA-EU) The Cancer Genome Atlas- (TCGA-) KIRC, respectively. ConsensusClusterPlus was used identify...
The effects of lignin-combined manganese ion, iron and on the decomposition hydrogen peroxide were investigated. Elemental analysis inductively coupled plasma-atomic emission spectrometry used to analyze chemical features lignin composites amount metal ions present in solution or adsorbed lignin, respectively. results showed that main transition elements remaining precipitated Fe, Mn, Cu. presence was represented by pseudo-first-order kinetics, rate constant (kobs) with 0.0068 min-1, while...
Fe–Cu systems, model alloys of nuclear reactor pressure vessel (RPV) steels, heat treatments by annealing and quenching, are studied the positron annihilation technique high‐resolution SEM. The different effect quenching on formation Cu precipitates was discussed. ultrafine precipitates, which formed in Fe– x wt.% ( = 1.0 1.5) after thermal annealing, observed clearly no obvious were found quenched alloys. temperature has an concentration leads to a change proportion this can be reflected W...
Abstract Radon is a naturally occurring radioactive inert gas that poses significant threat to the human health. Coconut shell activated carbon has been verified be best radon adsorbing material, but its adsorption capacity still cannot meet requirement of industrial applications. Activated modification using liquid nitrogen an effective method for improving capacity, it necessary determine conditions large-scale production. In this study, influence environmental temperature, container...
Cytoskeleton-associated protein 4 (CKAP4) acts as a key transmembrane that connects the endoplasmic reticulum (ER) to microtubule dynamics. Researchers have not examined roles of CKAP4 in nasopharyngeal carcinoma (NPC). The study aimed at evaluating prognostic value and metastasis-regulating effect NPC. could be observed 86.36% 557 NPC specimens but normal epithelial tissue. According immunoblot assays, cell lines presented high expression relative NP69 immortalized cells. Moreover, was...
Esophagus cancer (ESCA) is the sixth most frequent in males, with 5-year overall survival of 15%-25%. RNA modifications function critically progression, and m6A regulators are associated ESCA prognosis. This study further revealed correlations between development. Univariate Cox regression analysis consensus clustering were applied to determine molecular subtypes. Functional pathways gene ontology terms enriched by set enrichment analysis. Protein-protein interaction (PPI) on differentially...
Background: Although immune checkpoint inhibitors have opened a new mode of treatment for solid tumors, their efficacy in nasopharyngeal carcinoma (NPC) needs to be further investigated.Inhibitors the PD-1/PD-L1 are one hot topics tumor immunotherapy.Programmed death ligand-2 (PD-L2) is less studied ligand PD-1 and has not yet been fully explored, especially NPC.Understanding clinical significance PD-L2 expression, together with cell infiltration, might provide clues biomarker screening NPC...
To verify the accuracy and effectiveness of Goldengate high-throughput deafness gene chip in detecting patients with enlarged vestibular aqueduct syndrome(EVAS), to provide a reference for genetic detection strategy EVAS.
The atomic-scale defects such as (deuterium, helium)-vacancy clusters in nuclear energy materials are one of the causes for deterioration macroscopic properties materials. Unfortunately, they cannot be observed by transmission electron microscopy (TEM) before grow to nanometer scale. Positron annihilation spectroscopy (PAS) has been proven sensitive open-volume defects, and could characterize evolution size concentration vacancy-like nanoclusters. We have investigated effects He-D...
Nitrogen-doped biochar performs much better in dye adsorption due to its rich functional groups. Soybean cake, a by-product of soybean oil production, comprises contents cellulose, lignin, and protein. Therein, simple direct carbonization was utilized prepare self-nitrogen-doped (SCB). The results showed that the N content SCB 6.81 wt%, specific surface area 18.8 m2/g. X-ray photoelectron spectroscopic confirmed pyridine-N, pyrrole-N, graphite-N, oxidized-N capacity for Rhodamine B 17.2...
Objective To determine the optimal electron beam energy at different field size through a Monte Carlo-based simulation of therapy head Varian IX 6 MV linear accelerator so as to study influence radial intensity on depth dose. Methods Firstly, keeping unchanged for interest while changing energy, compassion was carried out calculated percentage doses between measured values. Thus, identified this size. Then, obtained set value doses. Results The 4 cm×4 cm, 10 cm×10 20 cm×20 cm...