A5030976076- Hidradenitis Suppurativa and Treatments
- Colorectal and Anal Carcinomas
- Anorectal Disease Treatments and Outcomes
- Microscopic Colitis
- Skin Protection and Aging
- Dermatology and Skin Diseases
- Cutaneous Melanoma Detection and Management
- melanin and skin pigmentation
- Autoimmune and Inflammatory Disorders
- Acne and Rosacea Treatments and Effects
- Chemotherapy-related skin toxicity
- Oral Health Pathology and Treatment
- Cancer and Skin Lesions
- Hair Growth and Disorders
- Nonmelanoma Skin Cancer Studies
- Contact Dermatitis and Allergies
- Allergic Rhinitis and Sensitization
- Cervical Cancer and HPV Research
- Parvovirus B19 Infection Studies
- Nuclear Structure and Function
- Consumer Behavior in Brand Consumption and Identification
- Nail Diseases and Treatments
- Inflammatory Bowel Disease
- Advancements in Transdermal Drug Delivery
- Cutaneous lymphoproliferative disorders research
Medizinische Hochschule Brandenburg Theodor Fontane
2019-2025
Städtisches Klinikum Dessau
2014-2024
Hidradenitis Suppurativa Foundation
2019-2024
National and Kapodistrian University of Athens
2007
A validated tool for the dynamic severity assessment of hidradenitis suppurativa/acne inversa (HS) is lacking. To develop and validate a novel scoring system to assess HS. Delphi voting procedure was conducted among members European Hidradenitis Suppurativa Foundation (EHSF) achieve consensus towards an initial HS Severity Score System (HS4). Strengths weaknesses HS4 were examined by multicentre prospective study. Multivariate logistic regression, discriminant analysis receiver operating...
Summary The S2k guideline on hidradenitis suppurativa/acne inversa (HS/AI) aims to provide an accepted decision aid for the selection/implementation of appropriate/sufficient therapy. HS/AI is a chronic recurrent, inflammatory, potentially mutilating skin disease terminal hair follicle‐glandular apparatus, with painful, inflammatory lesions in apocrine gland‐rich regions body. Its point prevalence Germany 0.3%, it diagnosed delay 10.0 ± 9.6 years. Abnormal differentiation keratinocytes...
Abstract Background The large unmet need of hidradenitis suppurativa/acne inversa ( HS ) therapy requires the elucidation disease‐driving mechanisms and tissue targeting. Objective Robust characterization underlying detection involved skin compartments. Methods Hidradenitis molecular taxonomy key signalling pathways were studied by whole transcriptome profiling. Dysregulated genes detected comparing lesional non‐lesional obtained from female patients matched healthy controls using Agilent...
The chronic, inflammatory skin disorder hidradenitis suppurativa (HS) is associated well documented negative influences on patients' quality of life (QoL). aim this study was to present more robust data QoL impairment by demographic and its correlation with well-known HS risk factors a cohort 1795 German patients. instrument used for measuring in the Dermatology Life Quality Index (DLQI). Overall, patients reported very large effect their (mean DLQI: 13.2 ± 8.1 points), 22% analyzed...
Zusammenfassung Ziel der S2k-Leitlinie zur Therapie Hidradenitis suppurativa/Acne inversa (HS/AI) ist es, eine akzeptierte Entscheidungshilfe für die Auswahl sowie Durchführung einer geeigneten/suffizienten von Patienten mit HS/AI zu liefern. chronisch rezidivierende, entzündliche, potenziell mutilierende Hauterkrankung des terminalen Haartalgdrüsenapparats, sich schmerzhaften, entzündlichen Läsionen in den apokrinen drüsenreichen Körperregionen manifestiert, insbesondere axillären Inguinal-...
<b><i>Introduction:</i></b> Hidradenitis suppurativa (HS) is a chronic inflammatory disorder of the pilosebaceous unit, often affecting and deforming intimate regions. HS associated with severe pain, pruritus, constant, purulent, malodorous discharge expected to impair sexual health patients. <b><i>Methods:</i></b> We performed cross-sectional, multicentric study involving 199 German patients from services research project “Epidemiology Care in...
Hidradenitis suppurativa (HS), also referred to as acne inversa, is a debilitating skin disease characterized by inflammatory nodules, chronic abscesses and tunnels (fistulae sinuses). The association with pilonidal sinus (PSD) frequently reported but not well documented.To determine the prevalence characteristics of lesions located in intergluteal fold (IGF) patients HS.This was an international multicentre retrospective cross-sectional study based on data collection from large cohort HS...
Abstract Aged skin exhibits disturbed lipid barrier, angiogenesis, production of sweat, immune functions, and calcitriol synthesis as well the tendency towards development certain benign or malignant diseases. These complex biological processes comprise endogenous exogenous factors. Ethnicity also markedly influences phenotype aging. The theories cellular senescence, telomere shortening decreased proliferative capacity, mitochondrial DNA single mutations, inflammation theory, free radical...