M. Delage

ORCID: 0000-0003-4310-7214
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About
Contact & Profiles
Research Areas
  • Hidradenitis Suppurativa and Treatments
  • Colorectal and Anal Carcinomas
  • Anorectal Disease Treatments and Outcomes
  • Autoimmune and Inflammatory Disorders
  • Microscopic Colitis
  • Chemotherapy-related skin toxicity
  • Acne and Rosacea Treatments and Effects
  • Oral Health Pathology and Treatment
  • Streptococcal Infections and Treatments
  • Histiocytic Disorders and Treatments
  • Inflammatory Myopathies and Dermatomyositis
  • Antimicrobial Resistance in Staphylococcus
  • Spondyloarthritis Studies and Treatments
  • Genetic and rare skin diseases.
  • Body Image and Dysmorphia Studies
  • Death, Funerary Practices, and Mourning
  • Health, Medicine and Society
  • CNS Lymphoma Diagnosis and Treatment
  • Cancer and Skin Lesions
  • Forensic Toxicology and Drug Analysis
  • Renal Transplantation Outcomes and Treatments
  • Renal Diseases and Glomerulopathies
  • Patient-Provider Communication in Healthcare
  • Sympathectomy and Hyperhidrosis Treatments
  • Meningioma and schwannoma management

Institut Pasteur
2015-2024

Université Paris Cité
2022-2024

Assistance Publique – Hôpitaux de Paris
2015-2017

Hôpital Avicenne
2013-2017

Inserm
2014

Centre Hospitalier Universitaire de Tours
2008-2013

Hôpital Dupuytren
1992-2012

Université de Tours
2008-2012

Clinica Santa Maria
2008

Centre Hospitalier Universitaire de Limoges
1992-2007

Hidradenitis suppurativa (HS) is a frequent and severe disease of the skin, characterized by recurrent or chronic skinfold suppurative lesions with high impact on quality life. Although considered inflammatory, antimicrobial treatments can improve lead to clinical remission HS, suggesting triggering microbial factors. Indeed, mixed anaerobic microbiota are associated majority HS lesions. Our aim in this study was characterize landscape infections using high-throughput sequencing.We sampled...

10.1093/cid/cix285 article EN Clinical Infectious Diseases 2017-03-28

Hidradenitis suppurativa (HS) is an inflammatory skin disease typically localized in the axillae and inguinal perineal areas. In absence of standardized medical treatment, severe HS patients present chronic suppurative lesions with polymicrobial anaerobic abscesses. Wide surgery cornerstone treatment HS, but surgical indications are limited by extent lesions. Intravenous broad-spectrum antibiotics may help control their efficacy not documented. This study was designed to assess a 6 week...

10.1093/jac/dkv361 article EN Journal of Antimicrobial Chemotherapy 2015-11-12

Hidradenitis suppurativa (HS) is a chronic skin disorder of unknown etiology that manifests as recurrent, painful lesions. Cutaneous dysbiosis and unresolved inflammation are hallmarks active HS, but their origin interplay remain unclear. Our metabolomic profiling HS revealed an abnormal induction the kynurenine pathway tryptophan catabolism in dermal fibroblasts, correlating with release pathway–inducing cytokines by inflammatory cell infiltrates. Notably, overactivation lesional was...

10.1172/jci.insight.140598 article EN cc-by JCI Insight 2020-09-24

Treatment of hidradenitis suppurativa (HS) is often unsatisfactory. The efficacy infliximab for treatment the disease has been suggested. main objective this study was to evaluate and side-effects in moderate severe HS, resistant local systemic treatments. secondary determine whether inflammation blood test results were changed. A retrospective monocentric all patients seen consecutively HS treated with performed. median six intravenous infusions (range 3-19) end-points self-improvement...

10.2340/00015555-1025 article EN Acta Dermato Venereologica 2011-01-01

Nearly half of patients with hidradenitis suppurativa (HS) report dissatisfaction their treatment. However, factors related to treatment satisfaction have not been explored.To measure associations between and clinical treatment-related characteristics among HS.Treatment was evaluated utilizing data from a cross-sectional global survey HS recruited 27 institutions, mainly referral centres, in 14 different countries October 2017 July 2018. The primary outcome patients' self-reported overall...

10.1111/bjd.21798 article EN British Journal of Dermatology 2022-07-30

Abstract Background We lack data on how physicians can instill confidence in patients. Objectives aimed to determine whether dress style (professional white coat or formal, semiformal casual attire) affects the physician by patients (children, teenagers, adults) with dermatology complaints consulting hospital private practice. Methods Design. D escriptive prospective cross sectional study carried out from July 1, 2008 2009. Setting. Outpatients department of a French tertiary care hospital,...

10.1111/j.1468-3083.2012.04665.x article EN Journal of the European Academy of Dermatology and Venereology 2012-08-09

Acne fulminans (AF) and hidradenitis suppurativa (HS) are 2 severe conditions with no consensus on medical treatment clear pathophysiology.1,2 We report the remission of long-lasting AF HS that was unresponsive to many previous treatments.

10.1016/j.jdcr.2019.04.001 article EN cc-by-nc-nd JAAD Case Reports 2019-06-01

An 83-year-old man was evaluated for a 1-year history of pruritic, progressively worsening migratory rash, with associated weakness and 5-kg weight loss. He had 30-pack-year smoking; he stopped smoking 45 years earlier. On examination, erythematous skin lesions that appeared in concentric, raised, serpiginous bands, desquamation (Panel A). The rash affected mainly the trunk proximal extremities. A clinical diagnosis erythema gyratum repens made. computed tomographic scan revealed pulmonary...

10.1056/nejmicm0906654 article EN New England Journal of Medicine 2010-05-12
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