A5055594389- Hidradenitis Suppurativa and Treatments
- Immunodeficiency and Autoimmune Disorders
- Disaster Response and Management
- Antifungal resistance and susceptibility
- Neutrophil, Myeloperoxidase and Oxidative Mechanisms
- Anorectal Disease Treatments and Outcomes
- Pneumocystis jirovecii pneumonia detection and treatment
- Streptococcal Infections and Treatments
- Legionella and Acanthamoeba research
- Viral Infections and Outbreaks Research
- Colorectal and Anal Carcinomas
- Pancreatitis Pathology and Treatment
- Urticaria and Related Conditions
- Influenza Virus Research Studies
- Blood disorders and treatments
- Hepatitis Viruses Studies and Epidemiology
- Abdominal Trauma and Injuries
- Platelet Disorders and Treatments
- Adrenal Hormones and Disorders
- Travel-related health issues
- Cytomegalovirus and herpesvirus research
- Bacillus and Francisella bacterial research
- Fungal Infections and Studies
- Bioactive Natural Diterpenoids Research
- Atherosclerosis and Cardiovascular Diseases
Assistance Publique – Hôpitaux de Paris
2011-2020
Centre de Référence Déficits Immunitaires Héréditaires
2012-2020
Hôpital Necker-Enfants Malades
2008-2019
Institut des Maladies Génétiques Imagine
2016-2019
Institut Pasteur
2015-2017
Délégation Paris 5
2011-2017
Sorbonne Paris Cité
2013-2017
Université Paris Cité
2008-2017
Sorbonne Université
2013-2015
Descartes (Belgium)
2014
Hidradenitis suppurativa (HS) is a skin disease characterized by recurrent nodules or abscesses and chronic suppurating lesions. In the absence of clear pathophysiology, HS considered to be an inflammatory has no satisfactory medical treatment. Recently, prolonged antimicrobial treatments were shown improve resolve We prospectively studied microbiology 102 lesions sampled from 82 patients using bacterial cultures metagenomics on 6 samples. Staphylococcus lugdunensis was cultured as unique...
Hidradenitis suppurativa (HS) is a frequent and severe disease of the skin, characterized by recurrent or chronic skinfold suppurative lesions with high impact on quality life. Although considered inflammatory, antimicrobial treatments can improve lead to clinical remission HS, suggesting triggering microbial factors. Indeed, mixed anaerobic microbiota are associated majority HS lesions. Our aim in this study was characterize landscape infections using high-throughput sequencing.We sampled...
Hidradenitis suppurativa (HS) is an inflammatory skin disease typically localized in the axillae and inguinal perineal areas. In absence of standardized medical treatment, severe HS patients present chronic suppurative lesions with polymicrobial anaerobic abscesses. Wide surgery cornerstone treatment HS, but surgical indications are limited by extent lesions. Intravenous broad-spectrum antibiotics may help control their efficacy not documented. This study was designed to assess a 6 week...
Although prognosis of Chronic Granulomatous Disease (CGD) has greatly improved, few studies have focused on its long-term outcome. We studied the clinical course and sequelae CGD patients diagnosed before age 16, at various adult time points.Cross-sectional French nationwide retrospective study screened through National Reference Center for Primary Immunodeficiencies (CEREDIH) registry.Eighty (71 males [88.7%], 59 X-linked [73.7%], median 23.9 years [minimum, 16.6; maximum, 59.9]) were...
Iatrogenic Cushing's syndrome is an undesirable outcome of glucocorticoids treatment. It can be increased by pharmacologic interactions. Glucocorticoid therapy, given in association with ritonavir, and some azole treatments are causes iatrogenic syndrome. We present a patient common-variable immunodeficiency who received 7 years itraconazole therapy for bronchial colonization Aspergillus combination inhaled fluticasone without any Cushingoid symptoms. After switch to posaconazole, the developed
Acne fulminans (AF) and hidradenitis suppurativa (HS) are 2 severe conditions with no consensus on medical treatment clear pathophysiology.1,2 We report the remission of long-lasting AF HS that was unresponsive to many previous treatments.
The emergence of the Ebola virus disease (EVD) outbreak in West Africa threatens regional and global public health security. This epidemic, first announced March 2014 Guinea Conakry, has grown dramatically since June with an extension into Liberia Sierra Leone. Nigeria, Mali, Democratic Republic Congo were also transiently affected. It was declared to be a emergency international concern by World Health Organization (WHO) on 8 August 2014. On 21 January 2015, cumulative total more than...