A5049146697- Nutrition and Health in Aging
- Frailty in Older Adults
- Intensive Care Unit Cognitive Disorders
- Dementia and Cognitive Impairment Research
- Electrolyte and hormonal disorders
- Balance, Gait, and Falls Prevention
- Pharmaceutical Practices and Patient Outcomes
- Stroke Rehabilitation and Recovery
- Neuroinflammation and Neurodegeneration Mechanisms
- Health and Wellbeing Research
- Thermoregulation and physiological responses
- Body Composition Measurement Techniques
- Sleep and Wakefulness Research
- Infrared Thermography in Medicine
- Sleep and related disorders
- Multiple Sclerosis Research Studies
- Cerebrovascular and Carotid Artery Diseases
- Pharmacological Effects and Toxicity Studies
- Optical Imaging and Spectroscopy Techniques
- Protein Tyrosine Phosphatases
- Health Systems, Economic Evaluations, Quality of Life
- Traumatic Brain Injury Research
- Hip and Femur Fractures
- Diet and metabolism studies
- Cardiovascular Health and Disease Prevention
Nagoya University
2017-2025
Japan Community Healthcare Organization
2023-2025
National Center for Geriatrics and Gerontology
2020-2023
Seirei Social Welfare Community
2022
National Institute for Japanese Language and Linguistics
2020
Fujita Health University Hospital
2020
Aim Among the many screening tools developed to detect frailty and disability in older adults, Clinical Frailty Scale (CFS) is a valid, reliable, easy‐to‐use tool has been translated into several languages. The aim of this study was demonstrate validity Japanese version CFS (CFS‐J). Methods necessary permissions were obtained from Rockwood colleagues. prepared by translation (English Japanese) verified back (Japanese English). Concurrent criterion assessed evaluating extent which relates...
Abstract Background Mild hyponatremia (serum sodium 130–135 mEq/L) is a common electrolyte disorder in the elderly. However, its association with both sarcopenia and cognitive function remains to be clarified. Therefore, here we investigated of mild skeletal muscle mass, physical function, Methods We enrolled 75 participants 2907 normonatremia sodium, 136–145 aged ≥70 years who visited Memory Disorder Outpatient Center Japan’s National for Geriatrics Gerontology. Skeletal mass index (SMI),...
We aimed to examine the association between intrinsic capacity (IC) and adverse outcomes of hospitalization.A prospective observational cohort study.We recruited patients aged 65 years or older who were admitted geriatric ward an acute hospital Oct 2019 Sep 2022.Each five IC domains (locomotion, cognition, vitality, sensory, psychological capacity) was graded into three levels, composite score calculated (0, lowest; 10, highest). Hospital-related defined as in-hospital death,...
Aim Polypharmacy has been reported to be associated with poor outcomes, including falls and frailty, in older populations. Past studies have found that slower walking speed is a good predictor of progression frank dementia mild cognitive impairment (MCI). Some the general population polypharmacy was gait speed; however, it remains elucidated whether affects even individuals MCI, who already some deterioration compared cognitively preserved individuals. The current study explored association...
Background: Few studies have examined the relationship between non-cognitive factors and activities of daily living (ADL) according to Alzheimer’s disease (AD) stage. Objective: We aimed identify differences in AD stages their involvement basic instrumental ADL performance by using intrinsic capacity (IC) groups with cognition ranging from normal moderate or severe AD. Methods: enrolled 6397 patients aged≥65 years who visited our memory clinic. Non-cognitive IC was assessed locomotion,...
Homocysteine is a common risk factor for cognitive impairment and sarcopenia. However, very few studies have shown an association between sarcopenia serum homocysteine levels after adjustment function.The purpose of this study was to investigate the relationship in memory clinic patients.This cross-sectional investigated outpatients clinic. We enrolled 1,774 participants (≥65 years old) with measured skeletal muscle mass index (SMI), hand grip strength (HGS), homocysteine. All had undergone...
Background: Polypharmacy, usually defined as the use of 5 or more drugs, is associated with reduced quality life, adverse events, and frailty. Slow gait speed a component physical frailty, some studies have suggested an association between polypharmacy slow speed. Objective: We aimed to determine effects on difference according stages cognitive decline in cross-sectional study memory clinic patients. Methods: Participants were 431 outpatients aged 65 year older who cognitively normal (CN)...
<title>Abstract</title> Purpose To examine the extent to which patients with amnestic mild cognitive impairment (aMCI) or Alzheimer’s disease (AD) perceive their own physical decline. Methods This study included 4585 outpatients (1036 normal cognition, 1712 aMCI, and 1837 AD) who visited a memory clinic. The families were asked about fear of falling, dizziness unsteadiness, knee pain, visual hearing impairment. Logistic regression analysis was performed relationship between concerns AD...
Neuromyelitis optica spectrum disorder (NMOSD) is an autoimmune demyelinating disease of the central nervous system. Although recent reports have noted that cognitive impairment common in NMOSD, little longitudinal information available on trajectories function disease. Here, we report a case 55-year-old woman with 11-year history NMOSD who visited our memory clinic for progressive loss. She was diagnosed early-onset Alzheimer based amyloid and tau positron emission tomography imaging...
Abstract Objectives: We aimed to examine the association between intrinsic capacity (IC) and adverse outcomes of hospitalization. Design: A prospective observational cohort study. Setting Participants: recruited patients aged 65 years or older who were admitted geriatric ward an acute hospital Oct 2019 Sep 2022. Measurements: Each five IC domains (locomotion, cognition, vitality, sensory, psychological capacity) was graded into three levels, composite score calculated (0, lowest; 10,...
Abstract Background: Mild hyponatremia (serum sodium 130-135 mEq/L) is a common electrolyte disorder in the elderly. However, its association with both sarcopenia and cognitive function remains to be clarified. Therefore, here we investigated of mild skeletal muscle mass, physical function, Methods: We enrolled 75 participants 2907 normonatremia sodium, 136-145 aged ≥ 70 years who visited Memory Disorder Outpatient Center Japan’s National for Geriatrics Gerontology. Skeletal mass index...
Abstract Background: Mild hyponatremia (serum sodium 130-135 mEq/L) is a common electrolyte disorder in the elderly. However, its association with both sarcopenia and cognitive function remains to be clarified. Therefore, here we investigated of mild skeletal muscle mass, physical function, Methods: We enrolled 75 participants 2872 normonatremia sodium, 136-145 aged ≥70 years who visited Memory Disorder Outpatient Center Japan’s National for Geriatrics Gerontology. Skeletal mass index (SMI),...
Abstract Background: Mild hyponatremia (serum sodium 130-135 mEq/L) is a common electrolyte disorder in the elderly. However, its association with both sarcopenia and cognitive function remains to be clarified. Therefore, here we investigated of mild skeletal muscle mass, physical function, Methods: We enrolled 75 participants 2907 normonatremia sodium, 136-145 aged ≥ 70 years who visited Memory Disorder Outpatient Center Japan’s National for Geriatrics Gerontology. Skeletal mass index...