A5113756416- Parasite Biology and Host Interactions
- Aquaculture disease management and microbiota
- Genomics and Phylogenetic Studies
- Myxozoan Parasites in Aquatic Species
- Gut microbiota and health
- Helminth infection and control
- Genetic diversity and population structure
- Nematode management and characterization studies
- Cancer Cells and Metastasis
- Protist diversity and phylogeny
- Sarcoma Diagnosis and Treatment
- Parasites and Host Interactions
- Aquatic Invertebrate Ecology and Behavior
- Child and Adolescent Psychosocial and Emotional Development
- Planarian Biology and Electrostimulation
- Renal cell carcinoma treatment
- Circular RNAs in diseases
- Early Childhood Education and Development
- Fish Biology and Ecology Studies
- Cancer-related molecular mechanisms research
- Marine Ecology and Invasive Species
- Environmental DNA in Biodiversity Studies
- Aquaculture Nutrition and Growth
- Microbial Community Ecology and Physiology
- MicroRNA in disease regulation
Chinese Academy of Sciences
2015-2024
State Key Laboratory of Freshwater Ecology and Biotechnology
2012-2024
Institute of Hydrobiology
2015-2024
Fujian Medical University
2018-2024
Union Hospital
2018-2024
University of Hong Kong
2011-2024
Second Affiliated Hospital of Zhejiang University
2022-2024
Shuguang Hospital
2024
Shanghai University of Traditional Chinese Medicine
2024
Beijing Normal University
2009-2023
Multigene and genomic data sets have become commonplace in the field of phylogenetics, but many existing tools are not designed for such sets, which often makes analysis time-consuming tedious. Here, we present PhyloSuite, a (cross-platform, open-source, stand-alone Python graphical user interface) user-friendly workflow desktop platform dedicated to streamlining molecular sequence management evolutionary phylogenetics studies. It uses plugin-based system that integrates several phylogenetic...
Gut microbiota has become an integral component of the host, and received increasing attention. However, for many domestic animals, information on is insufficient more effort should be exerted to manage gastrointestinal bacterial community. Understanding factors that influence composition microbial community in host alimentary canal essential or improve composition. In present study, 16S rRNA gene sequence-based comparisons communities grass carp (Ctenopharyngodon idellus) intestinal...
Abstract Phylogenetic analysis has entered the genomics (multilocus) era. For less experienced researchers, conquering large number of software programs required for a multilocus‐based phylogenetic reconstruction can be somewhat daunting and time‐consuming. PhyloSuite, with user‐friendly GUI, was designed to make this process more accessible by integrating multiple needed multilocus single‐gene phylogenies further streamlining whole process. In protocol, we aim explain how conduct each step...
Abstract Lipids are an essential component of living beings and important group nutrients. As the gut microbiota plays roles in intestinal absorption extraintestinal metabolism dietary lipids, current review addresses recent progress regarding interactions between lipid aquatic animals, with a focus on fish. We discuss detail how sources content affect composition microbiome mechanism by which affects host. This interaction is largely mediated via microbial lipases, short‐chain fatty acids...
Dietary intake affects the structure and function of microbes in host intestine. However, succession gut microbiota response to changes macronutrient levels during a long period time remains insufficiently studied. Here, we determined metabolic products intestinal grass carp (Ctenopharyngodon idellus) undergoing an abrupt extreme diet change, from fish meal Sudan (Sorghum sudanense). Grass hindgut responded rapidly shift, reaching new equilibrium approximately within 11 days. In comparison...
Although many anecdotes suggest that creative insights often arise during mind wandering, empirical research is still sparse. In this study, the number reduction task (NRT) was used to assess whether insightful solutions were related wandering incubation stage of process. An experience sampling paradigm provide an online measure while participants performed a sustained attention response (SART). Participants 91 Chinese college students. The results showed who gained hidden regularity in NRT...
Complete mitochondrial genomes are much better suited for the taxonomic identification and phylogenetic studies of nematodes than morphology or traditionally-used molecular markers, but they remain unavailable entire Camallanidae family (Chromadorea). As only published mitogenome in Camallanina suborder (Dracunculoidea superfamily) exhibited a unique gene order, other objective this research was to study evolution architecture Spirurida order. Thus, we sequenced complete Camallanus cotti...
Diet is known to influence intestinal microbiota in fish, but the specifics of these impacts are still poorly understood. Different protein/fibre ratio diets may result differing structures and activities gut microbiota. We examined hindgut microbiome grass carp (Ctenopharyngodon idellus) fed three different diets: fish meal (FM, high protein – low fibre), Sudan (SG, fibre protein) compound feed (CF, intermediate). Microbial profiles on FM were significantly from CF SG (F = 18.85, p < .01)....
Multi-gene and genomic datasets have become commonplace in the field of phylogenetics, but many existing tools are not designed for such datasets, which makes analysis time-consuming tedious. We therefore present PhyloSuite, a user-friendly workflow desktop platform dedicated to streamlining molecular sequence data management evolutionary phylogenetics studies. It employs plugin-based system that integrates number useful phylogenetic bioinformatic tools, thereby entire procedure, from...
Despite the economic importance of fish, ecology and metabolic capacity fish microbiomes are largely unknown. Here, we sequenced metatranscriptome intestinal microbiota grass carp, Ctenopharyngodon idellus, a freshwater herbivorous species. Our results confirmed previous work describing bacterial composition at phylum level as being dominated by Firmicutes, Fusobacteria, Proteobacteria Bacteriodetes. Comparative transcriptomes fed with different experimental diets indicated that influenced...
Abstract Membrane type 1-matrix metalloproteinase (MT1-MMP) is associated with enhanced tumorigenicity in many cancers. A recent study has revealed that MT1-MMP induces epithelial-to-mesenchymal transition (EMT) prostate and breast cancer cells. However, its role esophageal squamous cell carcinoma (ESCC) not been studied. Here, we investigated the of dissemination ESCC. Expression was detected by immunohistochemistry tissue microarray 88 Kazakh ESCC patients. Western blotting performed to...
Herbivorous grass carp (Ctenopharyngodon idellus) has a powerful capability to digest cellulose from aquatic plants, depending on the cellulase complex produced by cellulolytic bacterial community in gastrointestinal (GI) tract. However, it remains uncertain which bacteria taxa may actively participate digestion of food fibre. In this study, total 499 gut content fed Sudan (242 strains) and artificial feedstuffs (257 were randomly isolated characterized using carboxymethyl-cellulose,...
Abstract: Colon cancer is the third most common in world, with drug resistance and metastasis being major challenges to effective treatments. To overcome this, combination therapy different chemotherapeutics a practice. In this study, we demonstrated that paclitaxel (PTX) together BEZ235 exhibited synergetic inhibition effect on colon cell growth. Furthermore, nanoemulsion (NE)-loaded PTX were more than free drug, treatment of both NE drugs increased efficiency pretreatment before adding...
The development of emotion understanding in young Chinese preschoolers was examined. overall developmental trend, as measured by the Test Emotion Comprehension (TEC), proved similar to that found among Western Europe. However, children performed better at distinction between real and apparent worse connection reminders emotion. Children’s theory mind verbal ability were significant predictors their understand