A5101664704- Aquaculture Nutrition and Growth
- Reproductive biology and impacts on aquatic species
- Legal principles and applications
- Chinese history and philosophy
- China's Socioeconomic Reforms and Governance
- Polysaccharides Composition and Applications
- Ovarian function and disorders
- Antibiotic Resistance in Bacteria
- Gut microbiota and health
- Higher Education and Teaching Methods
- Plant Pathogens and Fungal Diseases
- Land Rights and Reforms
- Pregnancy and preeclampsia studies
- Proteins in Food Systems
- Aquaculture disease management and microbiota
- Hypothalamic control of reproductive hormones
- Legal and Constitutional Studies
- Genetic and Clinical Aspects of Sex Determination and Chromosomal Abnormalities
- Property Rights and Legal Doctrine
- Nanocomposite Films for Food Packaging
- Aquatic life and conservation
- Probiotics and Fermented Foods
- Pharmaceutical and Antibiotic Environmental Impacts
- Calpain Protease Function and Regulation
- TGF-β signaling in diseases
Hubei University of Technology
2022-2025
Southwest Petroleum University
2024
Huaiyin Normal University
2024
Wuhan Polytechnic University
2021-2023
Center of Hubei Cooperative Innovation for Emissions Trading System
2021-2023
Peking University
2015-2018
Institute of Hydrobiology
2015
Chinese Academy of Sciences
2015
York University
2013
National Institute of Environmental Health Sciences
2012
MicroRNAs (miRNAs) are small non-coding RNAs, which function as critical posttranscriptional regulators of gene expression by promoting mRNA degradation and translational inhibition. Placenta expresses many ubiquitous well specific miRNAs. These miRNAs regulate trophoblast cell differentiation, proliferation, apoptosis, invasion/migration, angiogenesis, suggesting that play important roles during placental development. Aberrant has been linked to pregnancy complications, such preeclampsia....
Abstract Background Influenza A viruses (IAVs) cause seasonal influenza epidemics and pose significant threats to public health. However, vaccines often elicit strain-specific immune responses confer little protection against mismatched strains. There is an urgent need develop universal emerging potentially re-emerging virus infections. Multiepitope combining multiple conserved epitopes can induce more robust broader provide a potential solution. Results Here, we demonstrated that HA...
Despite the economic importance of fish, ecology and metabolic capacity fish microbiomes are largely unknown. Here, we sequenced metatranscriptome intestinal microbiota grass carp, Ctenopharyngodon idellus, a freshwater herbivorous species. Our results confirmed previous work describing bacterial composition at phylum level as being dominated by Firmicutes, Fusobacteria, Proteobacteria Bacteriodetes. Comparative transcriptomes fed with different experimental diets indicated that influenced...
The effects of neuropeptide Y (NPY) on release growth hormone (GH) and gonadotropin (GTH) from the goldfish pituitary in vitro were investigated. Exposure perifused fragments, taken female at late stages gonadal recrudescence, to 5-min pulses human NPY resulted a rapid dose-dependent stimulation GH GTH release, with half-maximal effective dosages 0.51 ± 0.24 2.37 1.05 nM for GTH, respectively. Repeated treatments (10 GH, 5 GTH) 55-min intervals did not significantly alter responsiveness...
Influenza viruses pose a significant threat to global public health. Several influenza pandemic outbreaks have had serious economic and health implications. Current virus vaccines generally provide strain-specific protection must be rapidly produced annually match the circulating viruses. Developing that confer against broad range of will positive impact on In this study, we aimed develop ferritin-based nanoparticle vaccine with protective spectrum enhance immune response diverse We...
Abstract The effects of neuropeptide Y (NPY) on growth hormone (GH) and gonadotropin‐II (GtH‐II) release in different reproductive stages were studied using perfused pituitary fragments female goldfish. GH GtH‐II responses to 5‐min pulses NPY relatively small sexually regressed fish (July), intermediate recrudescent (December), maximal mature (= prespawning) (May). To test if sex steroids can modulate action, the vivo implantation 17β‐estradiol (E 2 ) testosterone (T) (both at 100 μg/g...
Konjac glucomannan (KGM)/agar blend films were obtained by casting at different drying temperatures (40 °C, 50 60 70 and 80 °C) an industrial scale. The effects of the temperature on microstructure, mechanical, water barrier properties investigated. results showed that lower led to enhanced H-bond interactions between KGM agar more ordered structures KGM/agar films, as evidenced FTIR X-ray analysis. Correspondingly, mechanical altered with film's structure significant differences (p < 0.05)...
Changes in serum levels of gonadotropin (GtH) and growth hormone (GH) gonadotropin-releasing (GnRH) the pituitary discrete brain areas were studied male goldfish during spawning with spontaneously ovulating females. Spontaneous ovulation females was induced by raising water temperature from 12 to 20 °C providing substrate artificial floating vegetation. Spawning occurs naturally sexually mature presence Serum GtH exposed ovulatory increased markedly synchrony surge There also a significant...
The gut microbiome plays important roles in maintaining host health, and inappropriate use of antibiotics can cause imbalance, which may contribute to serious disease. However, despite its promise, using metagenomic sequencing explore the effects colistin on composition pig has not been reported. Herein, we evaluated modulation pigs. Metagenomic analysis demonstrated that overall microbial diversity was higher group compared with control group. Antibiotic Resistance Genes Database following...
Colistin is considered as the last-resort treatment for multiantibiotic-resistant Gram-negative bacterial infections in humans. However, oral administration of colistin to livestock and poultry results introduction large amounts surrounding environment via urine feces, potentially inducing prevalence colistin-resistant bacteria impact on ecological environment. We established a quantitative mass spectrometry (MS) based method measure contents recovered from gastrointestinal segments piglets...
Activin has been suggested to be an autocrine/paracrine regulator in the human placenta. In present study, we examined expression of gene encoding activin type II receptor (ActRII) this tissue. Using primers corresponding published sequence ActRII, a 456bp fragment was obtained from cDNAs prepared placenta, as well ovary and brain, by polymerase chain reaction (PCR). Southern blot hybridization PCR products DNA cloning sequencing confirmed that product is authentic ActRII. Trophoblast cells...
can induce endothelial barrier damage in piglets, although the mechanism by which this pathogen triggers inflammatory remains unclear. Baicalin possesses anti-inflammatory and anti-oxidant activities. However, whether baicalin relieve caused
The gut microbiota is engaged in multiple interactions affecting host health, and dysbiosis can lead to many diseases. However, the effects of acetylcysteine (NAC) on microbiome composition pigs using metagenomic sequencing have not been reported. In this study, we used metagenome study NAC pig microbiome. Sequencing results showed that microbial diversity was changed after treatment. Antibiotic Resistance Genes Database (ARDB) analysis demonstrated main genes modified were macb, tsnr, norm,...
The gut microbiome exerts important functions on host health maintenance, whereas excessive antibiotic use may cause flora dysfunction resulting in serious disease and dysbiosis. Colistin is a broad-spectrum with resistance phenomena. However, it unclear whether colistin alters the gastrointestinal tract piglets. In this study, 16s rDNA-based metagenome analyses were used to assess effects of modification piglet stomach, duodenum, jejunum, cecum, feces. Both α- β-diversity indices showed...
Colistin has broad-spectrum activity against Gram-negative bacteria and been considered as the last-resort treatment for multiantibiotic-resistant infections in human. And it is also world widely utilized a veterinary medicine promotion of growth, prevention control diseases livestock poultry. Extensive use colistin husbandry results introduction large amounts to surrounding environment via animals' urine feces, potentially inducing prevalence resistance impact ecological environment. The...