Kai Chen

ORCID: 0000-0002-5395-3847
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About
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Research Areas
  • Metal and Thin Film Mechanics
  • Tribology and Wear Analysis
  • Orthopaedic implants and arthroplasty
  • Hydrogen embrittlement and corrosion behaviors in metals
  • Hydrogels: synthesis, properties, applications
  • Aluminum Alloys Composites Properties
  • Titanium Alloys Microstructure and Properties
  • Osteoarthritis Treatment and Mechanisms
  • Mechanical stress and fatigue analysis
  • Diamond and Carbon-based Materials Research
  • Advanced Sensor and Energy Harvesting Materials
  • Adhesion, Friction, and Surface Interactions
  • Electrospun Nanofibers in Biomedical Applications
  • Advanced materials and composites
  • Crystallization and Solubility Studies
  • X-ray Diffraction in Crystallography
  • Corrosion Behavior and Inhibition
  • Total Knee Arthroplasty Outcomes
  • Bone Tissue Engineering Materials
  • Geotechnical Engineering and Underground Structures
  • Magnesium Alloys: Properties and Applications
  • Numerical methods in engineering
  • Metallurgy and Material Forming
  • Advanced Welding Techniques Analysis
  • Surface Modification and Superhydrophobicity

China University of Mining and Technology
2016-2025

Hangzhou Dianzi University
2010-2025

Second Affiliated Hospital of Zhejiang University
2024-2025

Beijing Institute of Technology
2020-2025

Hubei University of Technology
2024-2025

Zhengzhou University of Aeronautics
2024-2025

Changshu Institute of Technology
2025

First Bethune Hospital of Jilin University
2025

Jilin Medical University
2025

Jilin University
2024-2025

Fast, continuous, 3D printing Although three-dimensional (3D) is now possible using relatively small and low-cost machines, it still a fairly slow process. This because printers require series of steps to cure, replenish, reposition themselves for each additive cycle. Tumbleston et al. devised process effectively grow solid structures out liquid bath. The key the creation an oxygen-containing “dead zone” between part precursor where solidification cannot occur. then renewed by upward...

10.1126/science.aaa2397 article EN Science 2015-03-16

Abstract Due to the moist environment and inevitable movement, efficient wound closure healing of vulnerable joint skin remains a great challenge. Herein, poly(γ‐glutamic acid)‐crosslinked amino‐functionalized PEGylated poly(glycerol sebacate) (γ‐PGA/PEGS‐NH 2 ) adhesive hydrogel is reported. PEGS‐NH γ‐PGA not only forms covalent amide bonds with biological tissue surfaces achieve strong adhesion but also establishes stable chemically crosslinked network in bulk hydrogels resist deformation....

10.1002/adfm.202109687 article EN Advanced Functional Materials 2021-12-01

Abstract Many hydrogel patches are developed to solve the pervasive and severe challenge of complex wound healing, while most them still lack satisfactory controllability comprehensive functionality. Herein, inspired by multiple creatures, including octopuses snails, a novel muti‐functional patch is presented with controlled adhesion, antibacterial, drug release features, monitoring functions for intelligent healing management. The micro suction‐cup actuator array tensile backing layer...

10.1002/advs.202301479 article EN cc-by Advanced Science 2023-06-27

Recently, zinc (Zn) and its alloys have demonstrated great potential as guided bone regeneration (GBR) membranes to treat the problems of insufficient alveolar volume long-term osseointegration instability during dental implantology. However, is a complex process consisting osteogenesis, angiogenesis, antibacterial function. For now, in vivo osteogenic performance activity pure Zn are inadequate, thus fabricating platform endow with multifunctions may be essential address these issues. In...

10.1021/acsami.3c16970 article EN ACS Applied Materials & Interfaces 2024-01-24

Abstract Dendritic cells (DCs) are the most potent antigen-presenting with multifaceted functions in controlling immune activation and tolerance. Graves' disease, particularly ophthalmopathy, is recognized as a refractory autoimmune thyroid disease. Therefore, DC-targeted therapies aimed at inducing specific tolerance important for treatment of we utilized polylactic acid glycolic polymer (PLGA) nanoparticles encapsulating disease auto-antigen thyrotropin receptor A (TSHR-A) peptide inducer...

10.1088/1748-605x/adbaa3 article EN Biomedical Materials 2025-02-26

We report the synthesis, structure, and properties of novel bulk rhenium nitrides, hexagonal ${\mathrm{Re}}_{2}\mathrm{N}$, ${\mathrm{Re}}_{3}\mathrm{N}$. Both phases have very high moduli $>400\text{ }\text{ }\mathrm{GPa}$, similar to most incompressible binary transition-metal (TM) carbides nitrides found date. However, in contrast other TM ${\mathrm{Re}}_{3}\mathrm{N}$ is better placed for potential technological applications, as it can be formed at relatively moderate pressures (13--16...

10.1103/physrevlett.105.085504 article EN Physical Review Letters 2010-08-20

Abstract Development of reporter genes for multimodality molecular imaging is highly important. In contrast to the conventional strategies which have focused on fusing several together serve as multimodal reporters, human tyrosinase (TYR) – key enzyme in melanin production was evaluated this study a stand-alone gene vitro and vivo photoacoustic (PAI), magnetic resonance (MRI) positron emission tomography (PET). Human breast cancer cells MCF-7 transfected with plasmid that encodes TYR (named...

10.1038/srep01490 article EN cc-by Scientific Reports 2013-03-19

To maximize the catalytic performance of MoS2 in hydrogen evolution reaction, we investigate electrocatalytic and photocatalytic monolayer doped with noble metal (Ag, Au, Cu, Pd, Pt) using first principles calculation combined climbing image nudged elastic band method. We find gap is reduced significantly by doping, which unfavorable to improving its performance. The optical absorption coefficient shows that doping does not increase ability absorb visible light. a potential photocatalyst for...

10.1016/j.nanoms.2020.05.001 article EN cc-by-nc-nd Nano Materials Science 2020-06-06

Magnesium alloys with integration of degradability and good mechanical performance are desired for orthopedic implants. In this paper, Mg-2Sr-Ca Mg-2Sr-Zn were prepared the degradation as well bone response investigated. Compared binary Mg-2Sr alloys, addition Ca Zn improved in vitro vivo corrosion resistance. exhibited more uniform maintained configuration implants 4 weeks post-implantation. The rates 0.85 mm/yr 1.10 comparison 1.37 Mg-2Sr. cell tests indicated that higher MG63 viability...

10.1016/j.bioactmat.2020.02.014 article EN cc-by-nc-nd Bioactive Materials 2020-02-25

Although the geochemical and mineralogical characteristics provenance of Permian-Triassic boundary (PTB) widespread volcanic ashes from southern China have been well investigated, just prior to end-Permian mass extinction (EPME) rarely studied. This paper presents compositions latest Permian coal-bearing strata southwest China. Based on relative abundances kaolinite mixed-layer illite/smectite (I/S), in present study can be divided into tonsteins K-bentonites, which are dominated by I/S,...

10.1016/j.coal.2021.103707 article EN cc-by-nc-nd International Journal of Coal Geology 2021-02-21
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