A5022839251- Natural Antidiabetic Agents Studies
- Parasites and Host Interactions
- African Botany and Ecology Studies
- Papaya Research and Applications
- Phytochemicals and Antioxidant Activities
- Seed and Plant Biochemistry
- Curcumin's Biomedical Applications
- Cholinesterase and Neurodegenerative Diseases
- Moringa oleifera research and applications
- Enzyme Production and Characterization
- Heavy Metal Exposure and Toxicity
- Parasite Biology and Host Interactions
- Cardiac electrophysiology and arrhythmias
- Global Maternal and Child Health
- Nuclear Receptors and Signaling
- Retinoids in leukemia and cellular processes
- Cassava research and cyanide
- Botany, Ecology, and Taxonomy Studies
- Nuts composition and effects
- Medicinal Plants and Neuroprotection
- Diverse Scientific Research Studies
- Coconut Research and Applications
- Phytochemicals and Medicinal Plants
- Medicinal Plant Research
- Advanced Glycation End Products research
Lagos State University
2020-2024
University of Zululand
2015-2019
University of Lagos
2014
In recent years, indigenous medicinal plants exhibiting diverse biological activities have been explored in the amelioration of hepatotoxicity. This study investigates protective effect Monodora myristica (MM) on cadmium-induced liver damage experimental animals. Male Wistar albino rats were maintained 200 mg/L cadmium: Cd (Cd as CdCl2) animals' main drinking water to induce Added this, animals received aqueous extracts MM at a dose or 400 and 20 mg/kg bw Livolin forte (LF) for 21 days. At...
Schistosomiasis sometimes referred to as bilharzia ranks high among the common neglected human tropical diseases. Parasitic trematode flatworm belonging genus Schistosoma is responsible for this acute and chronic disease. Its prevalence rapidly increasing in regions worldwide; however, its economic global health impact grossly underestimated. There are five recognized species of schistosome parasitizing humans but causing disease S. haematobium, japonicum mansoni. Over years, praziquantel,...
Purpose: To investigate the ameliorative effect of ethanolic extract Carica papaya leaves in alloxan - induced diabetic rats.Methods: Rats were randomly divided into five groups eight animals each. Group A (control) comprised normal healthy which orally administered 1.0 ml distilled water daily for 21 days while B – E consisted alloxan-induced rats. untreated rats, and C D received 250 mg/kg 500 body weight extract, respectively. 300 metformin.Results: Administration to rats significantly...
Background and Objective: Diabetes is an insidious as well a debilitating metabolic disease with variety of causes that could lead to severe
 complications in multiple organs within the body system. There has been no documented scientific evidence regards total cure this complex
 chronic disease; therefore, it demands lifelong management. This necessitated recent evaluation several plant derived foods costeffective
 alternatives management diabetes its associated...
Abstract Background Diabetes mellitus is a metabolic disorder which associated with debilitating complications including eye disease, kidney disorder, and diabetic foot disease. One of the mechanisms implicated in pathogenesis polyol pathway. This study evaluated inhibitory effect aqueous extract four tropical fruits, namely apple ( Malus domestica Borkh.), banana Musa paradisiaca Linn.), pawpaw Carica papaya watermelon Citrullus lanatus (Thunb.) Matsum & Nakai), on activities pathway...
Background and Objective: Diabetes is an insidious as well a debilitating metabolic disease with variety of causes that could lead to severe complications in multiple organs within the body system. There has been no documented scientific evidence regards total cure this complex chronic disease; therefore, it demands lifelong management. This necessitated recent evaluation several plant derived foods costeffective alternatives management diabetes its associated complication.Materials Methods:...
The contamination of edible agricultural goods with pesticides, including dichlorvos (DVDP), poses a substantial public health risk, promoting severe morbidity and mortality, especially in developing countries. It has been shown that hesperidin (hesperetin-7-O-rhamnoglucoside or Hes-7-RGlc) preserves cytomembrane, redox, lipid homeostasis; unfortunately, its function on dichlorvos-incited heart damage not investigated. This work explored the ameliorative influence Hes-7-RGlc DVDP-activated...
Organophosphorus pesticides such as dichlorvos (DDVP) are often employed to eradicate pests, especially in low and medium-income countries. However, they have several negative impacts on the visceral organs. Astonishingly, curcumin protects organs from detrimental effects of xenobiotics via maintenance redox homeostasis; unfortunately, its role dichlorvos-provoked multi-organ impairment vis-à-vis lipid homeostasis has not been examined. Therefore, this undertaking probed remedial efficacy...
Despite the number of nutritional and medicinal plant‐based products that have been studied for decades, there are still many rare underutilized plants biological importance, whose biochemical properties unmatched, especially wild doum palm, Hyphaene thebaica . Therefore, it is necessary to unveil potential advantages fruit thebaica. The edible palm a rich source novel nutraceutical pharmaceutical constituents. It rare, but highly nutritious found in tropics, variety time‐proven healthy...
Purpose: Universal stress protein (USP) from Schistosoma mansoni, designated as G4LZI3, waspreviously hypothesised a druggable target and vaccine candidate for human schistosomiasis.The purpose of this study is to characterize purified recombinant G4LZI3 preliminarily forsubsequent structural characterization, which will provide baseline data futurefunctional studies the discovery, design development new schistosomal drugs thetreatment, control elimination schistosomiasis. Methods:...
Mitracarpus vilosus is widely used among the indegenes of Ibeju-Lekki area Lagos State for treatment skin lesions. This study elucidated phytochemical constituents in 80% methanolic leaf extract vilosus. Phytochemical screening and gas chromatography-mass spectrometry (GC-MS) analyses were carried out on extract. The qualitative showed presence following phytochemicals, tannins, terpenoids, saponins, cardiac glycosides steroids. screen did not reveal any flavonoids. However, Squalene 14.27%,...
Mitracarpus villosus which belongs to the family of Rubiaceae is one important medicinal plants widely known for its broad spectrum pharmacological activities and biological uses includes antioxidant, antimicrobial, anti-inflammatory, anti-cancer, anti-ulcer, antibacterial amongst others. It used in treatment various ailments such as ulcers, skin-related infections like dermatitis, eczema, psoriasis, acne. This study elucidated phytochemical properties flower. was achieved through methanolic...