A5036129918- Multiple Sclerosis Research Studies
- Peripheral Neuropathies and Disorders
- Ocular Diseases and Behçet’s Syndrome
- Retinal and Optic Conditions
- Systemic Lupus Erythematosus Research
- Cerebral Venous Sinus Thrombosis
- IgG4-Related and Inflammatory Diseases
- Carbon Nanotubes in Composites
- Traumatic Brain Injury and Neurovascular Disturbances
- Chronic Lymphocytic Leukemia Research
- Advanced Electron Microscopy Techniques and Applications
- Cancer Genomics and Diagnostics
- Catalysts for Methane Reforming
- Breast Cancer Treatment Studies
- Otitis Media and Relapsing Polychondritis
- Nanopore and Nanochannel Transport Studies
- Electron and X-Ray Spectroscopy Techniques
- Amyloidosis: Diagnosis, Treatment, Outcomes
- Surface and Thin Film Phenomena
- Intraoperative Neuromonitoring and Anesthetic Effects
- Inflammasome and immune disorders
- Cancer Treatment and Pharmacology
- Immunotherapy and Immune Responses
- Advanced Neuroimaging Techniques and Applications
- Reproductive System and Pregnancy
Chinese People's Liberation Army
2022-2025
Chinese General Hospital College of Nursing and Liberal Arts
2024
Chinese PLA General Hospital
2020-2024
Stanford University
2023-2024
People's Liberation Army No. 150 Hospital
2022
PLA Academy of Military Science
2022
Fudan University Shanghai Cancer Center
2020
Abstract Four-dimensional scanning transmission electron microscopy (4D-STEM) has recently gained widespread attention for its ability to image atomic electric fields with sub-Ångstrom spatial resolution. These field maps represent the integrated effect of nucleus, core electrons and valence electrons, separating their contributions is non-trivial. In this paper, we utilized simultaneously acquired 4D-STEM center mass (CoM) images annular dark (ADF) determine projected charge density in...
Objective The aim of this study was to compare the efficacy low-dose rituximab (RTX) and immunosuppressants in treating orbital inflammatory pseudotumor (OIP) with intracranial extension, a refractory high-relapse disease. Methods Patients who had been diagnosed OIP extension were systemic corticosteroids retrospectively recruited at Neuro-Ophthalmology Department Chinese People’s Liberation Army General Hospital between December 2018 September 2022. After methylprednisolone pulse therapy,...
Neuromyelitis Optica (NMO) is a neuroimmune disorder primarily driven by autoantibodies against aquaporin 4 (AQP4), known as NMO-IgG. Although the mechanisms underlying NMO-IgG-induced retinopathy are not fully understood, high expression of AQP4 in retinal Müller cells suggests direct interaction that may trigger inflammatory processes retina. Previous studies indicate microglia play critical role mediating immune responses, leading to neuronal dysfunction. NMO-IgG obtained from clinical...
Background Several neuroimaging studies demonstrated that optic neuritis (ON) leads to functional and anatomical architecture changes in the brain. The alterations of interhemispheric connectivity (IFC) patients with AQP4-ON myelin oligodendrocyte glycoprotein (MOG)-ON are not well understood. Purpose To investigate differential patterns VMHC MOG-ON. Material Methods Twenty-one AQP4-ON, 11 MOG-ON, 34 healthy controls underwent resting-state MRI scans. One-way ANOVA was used identify regions...
Abstract Because of their large surface areas, nanotubes and nanowires demonstrate exquisite mechanical coupling to surroundings, promising advanced sensors nanomechanical devices. However, this environmental sensitivity has resulted in several ambiguous observations vibrational across various experiments. Herein, we a temperature-dependent Radial Breathing Mode (RBM) frequency free-standing, electron-diffraction-assigned Double-Walled Carbon Nanotubes (DWNTs) that shows an unexpected...
<title>Abstract</title> Purpose A high incidence of clinical optic disc edema in altitudes has been shown; however, almost all patients completely regress on return to lowlands and do not complain visual symptoms such as vision loss or field defect. Here, we report six with remarkably decreased function after high-altitude exposure, which diagnosis nonarteritic anterior ischaemic neuropathy (NAION). Methods Clinical characteristics, intracranial pressure, testing for risk factors associated...
<title>Abstract</title> Background Neuromyelitis Optica (NMO) is a neuroimmune disorder primarily driven by autoantibodies against aquaporin 4 (AQP4), known as NMO-IgG. Although the mechanisms underlying NMO-IgG-induced retinopathy are not fully understood, high expression of AQP4 in retinal Müller cells suggests direct interaction that may trigger inflammatory processes retina. Previous studies indicate microglia play critical role mediating immune responses, leading to neuronal...
This study aimed to investigate the clinical spectra and outcomes in pregnancy-related optic neuritis (ON).We analyzed subtype prognosis of women with ON neuro-ophthalmology department First Medical Center at Chinese PLA General Hospital from January 2014 December 2019.A total 54 patients, including 21 (38.9%) idiopathic (ION), 27 (50.0%) aquaporin-4 (AQP4)-ON, 6 (11.6%) myelin oligodendrocyte glycoprotein (MOG)-ON, who experienced 58 informative pregnancies 67 episodes were assessed. Among...
Objective To investigate the clinical, laboratory and imaging evaluation, treatment prognosis of patients with idiopathic hypertrophic pachymeningitis (IHP) ophthalmic manifestations as first symptom. Methods A retrospective case analysis. Eight displaying symptoms IHP were recruited from Neuro-ophthalmology Department in First Medical Center Chinese PLA General Hospital January 2016 to April 2019 inculed this study. There 6 males 2 females, aged 11 65 years, an average age...