A5078816723- Zoonotic diseases and public health
- Viral Infections and Vectors
- Animal Disease Management and Epidemiology
- Mosquito-borne diseases and control
- COVID-19 epidemiological studies
- Viral Infections and Outbreaks Research
- Bat Biology and Ecology Studies
- Marine animal studies overview
- Animal Vocal Communication and Behavior
- Malaria Research and Control
- Climate Change and Health Impacts
- Disaster Response and Management
- Yersinia bacterium, plague, ectoparasites research
- Evolution and Genetic Dynamics
- Species Distribution and Climate Change
- Herpesvirus Infections and Treatments
- Animal Virus Infections Studies
- Wildlife Ecology and Conservation
- Bacteriophages and microbial interactions
- Bioinformatics and Genomic Networks
- Genomics and Phylogenetic Studies
- Bacillus and Francisella bacterial research
- Poxvirus research and outbreaks
- Vector-Borne Animal Diseases
- HIV Research and Treatment
University College London
2017-2025
London School of Hygiene & Tropical Medicine
2021-2024
Wolters Kluwer (Netherlands)
2024
Centre for Australian National Biodiversity Research
2024
Zoological Society of London
2017
Abstract High‐throughput environmental sensing technologies are increasingly central to global monitoring of the ecological impacts human activities. In particular, recent boom in passive acoustic sensors has provided efficient, noninvasive, and taxonomically broad means study wildlife populations communities, monitor their responses change. However, until recently, technological costs constraints have largely confined research ( PAM ) a handful taxonomic groups (e.g., bats, cetaceans,...
Passive acoustic sensing has emerged as a powerful tool for quantifying anthropogenic impacts on biodiversity, especially echolocating bat species. To better assess population trends there is critical need accurate, reliable, and open source tools that allow the detection classification of calls in large collections audio recordings. The majority existing are commercial or have focused species task, neglecting important problem first localizing echolocation which particularly problematic...
Emerging infectious diseases, biodiversity loss, and anthropogenic environmental change are interconnected crises with massive social ecological costs. In this Review, we discuss how pathogens parasites responding to global change, the implications for pandemic prevention conservation. Ecological evolutionary principles help explain why both pandemics wildlife die-offs becoming more common; land-use loss often followed by an increase in zoonotic vector-borne diseases; some species, such as...
Abstract Biodiversity continues to decline under the effect of multiple human pressures. We give a brief overview main pressures on biodiversity, before focusing two that have predominant effect: land-use and climate change. discuss how interactions between change in terrestrial systems are likely greater impacts than expected when only considering these isolation. Understanding biodiversity changes is complicated by fact such be uneven among different geographic regions species. review...
Better understanding of how environmental changes affect pathogens, hosts, and disease vectors can help prevent respond to zoonoses, write Rory Gibb colleagues Climate change biodiversity loss are among this century's greatest threats human health exposing people worldwide increasing food water insecurity, extreme weather, pollution, infectious threats.12 Zoonotic diseases situated at nexus between change, ecosystems, health. pathogens parasites maintained in an animal reservoir regularly or...
In the light of urgency raised by COVID-19 pandemic, global investment in wildlife virology is likely to increase, and new surveillance programmes will identify hundreds novel viruses that might someday pose a threat humans. To support extensive task laboratory characterization, scientists may increasingly rely on data-driven rubrics or machine learning models learn from known zoonoses which animal pathogens could health. We synthesize findings an interdisciplinary workshop zoonotic risk...
Animals and their viruses are connected by a sprawling, tangled network of species interactions. Data on the host-virus available from several sources, which use different naming conventions often report metadata in levels detail.
Dengue is expanding globally, but how dengue emergence shaped locally by interactions between climatic and socio-environmental factors not well understood. Here, we investigate the drivers of incidence in Vietnam, through analysing 23 years district-level case data spanning a period significant socioeconomic change (1998-2020). We show that urban infrastructure (sanitation, water supply, long-term growth) predict local spatial patterns incidence, while human mobility more influential driver...
Abstract The recent global expansion of dengue has been facilitated by changes in urbanisation, mobility, and climate. In this work, we project future incidence case burden to 2099 under the latest climate change scenarios. We fit a statistical model province-level monthly counts from eight countries across Southeast Asia, one worst affected regions. that will peak century before declining lower levels with large variations between within countries. Our findings reveal northern Thailand...
Abstract Emerging infectious diseases are increasingly understood as a hallmark of the Anthropocene 1–3 . Most experts agree that anthropogenic ecosystem change and high-risk contact among people, livestock, wildlife have contributed to recent emergence new zoonotic, vector-borne, environmentally-transmitted pathogens 1,4–6 However, extent which these factors also structure landscapes human infection outbreak risk is not well understood, beyond certain well-studied disease systems 7–9 Here,...
Understanding how emerging infectious diseases spread within and between countries is essential to contain future pandemics. Spread new areas requires connectivity one or more sources a suitable local environment, but these two factors interact at different stages of disease emergence remains largely unknown. Further, no analytical framework exists examine their roles. Here we develop dynamic modelling approach for that explicitly models both via human movement environmental suitability...
Abstract Lassa fever is a longstanding public health concern in West Africa. Recent molecular studies have confirmed the fundamental role of rodent host ( Mastomys natalensis ) driving human infections, but control and prevention efforts remain hampered by limited baseline understanding disease’s true incidence, geographical distribution underlying drivers. Here, we show that occurrence incidence influenced climate, poverty, agriculture urbanisation factors. However, heterogeneous reporting...
Host-virus association data underpin research into the distribution and eco-evolutionary correlates of viral diversity zoonotic risk across host species. However, current knowledge wildlife virome is inherently constrained by historical discovery effort, there are concerns that reliability ecological inference from host-virus may be undermined taxonomic geographical sampling biases. Here, we evaluate whether estimates host-level in wild mammals stable enough to considered biologically...
Predicting host-virus interactions is fundamentally a network science problem. We develop method for bipartite prediction that combines recommender system (linear filtering) with an imputation algorithm based on low-rank graph embedding. test this by applying it to global database of mammal-virus and thus show makes biologically plausible predictions are robust data biases. find the mammalian virome under-characterized anywhere in world. suggest future virus discovery efforts could...
1. The natal multimammate mouse (Mastomys natalensis) is the primary reservoir host of Lassa mammarenavirus (LASV), a zoonotic pathogen causing fever that endemic to West Africa. occurrence and abundance this species regulated by human environment biotic interactions with other small-mammal species, but these ecological drivers remain poorly understood in regions where outbreaks are observed. 2. We developed Bayesian multi-species occupancy model incorporating incomplete detection assess...
Orthopoxviruses (OPVs), including the causative agents of smallpox and mpox have led to devastating outbreaks in human populations worldwide. However, discontinuation vaccination, which also provides cross-protection against related OPVs, has diminished global immunity OPVs more broadly. We apply machine learning models incorporating both host ecological viral genomic features predict likely reservoirs OPVs. demonstrate that addition traits enhanced accuracy potential OPV predictions,...
Due to their ability disperse over water, half of the extant bat species occur on islands and ca. 25% these are island endemics. They often sole native mammals play key roles in maintenance insular ecosystems. Yet, due increasing anthropogenic pressures, 60% island-restricted bats now threatened. The sub-tropical Madeira is home Macaronesian endemic Pipistrellus maderensis, Nyctalus leisleri verrucosus - an subspecies Plecotus austriacus. These each represent three main foraging guilds...
Global wind patterns affect flight strategies in many birds, including pelagic seabirds, of which use wind-powered soaring to reduce energy costs during at-sea foraging trips and migration. Such long-distance movement are underpinned by local interactions between conditions behaviour, but these fine-scale relationships far less well understood. Here we show that remotely sensed ocean speed direction highly significant predictors behaviour a migratory seabird, the Manx shearwater (Puffinus...
Abstract The fields of viral ecology and evolution are rapidly expanding, motivated in part by concerns around emerging zoonoses. One consequence is the proliferation host–virus association data, which underpin macroecology zoonotic risk prediction but remain fragmented across numerous data portals. In present article, we propose that synthesis a central challenge to characterize global virome develop foundational theory ecology. To illustrate this, build an open database mammal associations...