A5008710186- Viral Infections and Vectors
- Zoonotic diseases and public health
- SARS-CoV-2 and COVID-19 Research
- Mosquito-borne diseases and control
- Animal Disease Management and Epidemiology
- Vector-Borne Animal Diseases
- COVID-19 Clinical Research Studies
- Animal Virus Infections Studies
- COVID-19 epidemiological studies
- Rabies epidemiology and control
- Insect symbiosis and bacterial influences
- Viral Infections and Outbreaks Research
- Viral gastroenteritis research and epidemiology
- Long-Term Effects of COVID-19
- Bat Biology and Ecology Studies
- Antifungal resistance and susceptibility
- Social Media in Health Education
- Ethics in Clinical Research
- Malaria Research and Control
- Fungal Infections and Studies
- Ocular Infections and Treatments
- Virology and Viral Diseases
- Sex and Gender in Healthcare
- Marine animal studies overview
- Poxvirus research and outbreaks
Colorado State University
2012-2024
University of Rhode Island
2024
Centers for Disease Control and Prevention
2024
Epidemic Intelligence Service
2024
Colorado Health Foundation
2022
Vector (United States)
2022
Texas A&M University
2019
University of Georgia
2019
Coronavirus disease-19 (COVID-19) emerged in late 2019 China and rapidly became pandemic. As with other coronaviruses, a preponderance of evidence suggests the virus originated horseshoe bats ( Rhinolophus spp.) may have infected an intermediate host prior to spillover into humans. A significant concern is that SARS-CoV-2 could become established secondary reservoir hosts outside Asia. To assess this potential, we challenged deer mice Peromyscus maniculatus ) found robust replication upper...
In the light of urgency raised by COVID-19 pandemic, global investment in wildlife virology is likely to increase, and new surveillance programmes will identify hundreds novel viruses that might someday pose a threat humans. To support extensive task laboratory characterization, scientists may increasingly rely on data-driven rubrics or machine learning models learn from known zoonoses which animal pathogens could health. We synthesize findings an interdisciplinary workshop zoonotic risk...
Animals and their viruses are connected by a sprawling, tangled network of species interactions. Data on the host-virus available from several sources, which use different naming conventions often report metadata in levels detail.
Abstract Coronavirus disease-19 (COVID-19) emerged in November, 2019 China and rapidly became pandemic. As with other coronaviruses, a preponderance of evidence suggests the virus originated horseshoe bats ( Rhinolophus spp.) likely underwent recombination event an intermediate host prior to entry into human populations. A significant concern is that SARS-CoV-2 could become established secondary reservoir hosts outside Asia. To assess this potential, we challenged deer mice Peromyscus...
Arthropod-borne viruses (arboviruses) are transmitted to humans primarily through the bites of infected mosquitoes or ticks, and in continental United States, West Nile virus (WNV) is leading cause domestically acquired arboviral disease. Other arboviruses sporadic cases disease as well occasional outbreaks. This report summarizes 2021 surveillance data reported CDC by U.S. jurisdictions for nationally notifiable arboviruses; excludes chikungunya, dengue, yellow fever, Zika cases, because...
Abstract The outbreak and transmission of disease-causing pathogens are contributing to the unprecedented rate biodiversity decline. Recent advances in genomics have coalesced into powerful tools monitor, detect, reconstruct role impacting wildlife populations. Wildlife researchers thus uniquely positioned merge ecological evolutionary studies with genomic technologies exploit “Big Data” disease research; however, many lack training expertise required use these computationally intensive...
The growing threat of vector-borne diseases, highlighted by recent epidemics, has prompted increased focus on the fundamental biology vector-virus interactions. To this end, experiments are often most reliable way to measure vector competence (the potential for arthropod vectors transmit certain pathogens). Data from these critical understand outbreak risk, but - despite having been collected and reported a large range vector-pathogen combinations terminology is inconsistent, records...
The emergence of COVID-19 has led to a pandemic that caused millions cases disease, variable morbidity and hundreds thousands deaths. Currently, only remdesivir dexamethasone have demonstrated limited efficacy, slightly reducing disease burden, thus novel approaches for clinical management are needed. We identified panel human monoclonal antibody clones from yeast display library with specificity the SARS-CoV-2 spike protein receptor binding domain neutralized virus in vitro . Administration...
ABSTRACT From the first isolation of Zika virus (ZIKV) in Uganda 1947, ZIKV had primarily been associated with sporadic human cases Africa and Asia until emerged as an epidemic Americas 2015. As spread into new geographic regions, it now has potential to interact many novel host species whose susceptibility yet be determined. Mathematical models predict a sylvatic reservoir ZIKV, non-human primates (NHPs) likely candidates, though outbreaks areas without NHPs suggest presence other...
Insectivorous Old World horseshoe bats (Rhinolophus spp.) are the likely source of ancestral SARS-CoV-2 prior to its spillover into humans and causing COVID-19 pandemic. Natural coronavirus infections appear be principally confined intestines, suggesting fecal-oral transmission; however, little is known about biology SARS-related coronaviruses in bats. Previous experimental challenges Egyptian fruit (Rousettus aegyptiacus) resulted limited infection restricted respiratory tract, whereas...
Despite significant research efforts, treatment options for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) remain limited. This is due in part to a lack of therapeutics that increase host defense the virus. Replication SARS-CoV-2 lung tissue associated with marked infiltration macrophages and activation innate immune inflammatory responses amplify injury. Antagonists androgen (AR) glucocorticoid (GR) receptors have shown efficacy models COVID-19 clinical studies because cell...
Microbiology conferences can be powerful places to build collaborations and exchange ideas, but for queer transgender (trans) scientists, they also become sources of alienation isolation. Many conference organizers would like create welcoming inclusive events feel ill-equipped make this vision a reality, historical lack representation trans folks in microbiology means we rarely occupy these key leadership roles ourselves. Looking more broadly, scientists are systematically marginalized...
Insectivorous Old World horseshoe bats ( Rhinolophus spp.) are the likely source of ancestral SARS-CoV-2 prior to its spillover into humans and causing COVID-19 pandemic. Natural coronavirus infections appear be principally confined intestines, suggesting fecal-oral transmission; however, little is known about biology SARS-related coronaviruses in bats. Previous experimental challenges Egyptian fruit Rousettus aegyptiacus ) resulted limited infection restricted respiratory tract, whereas...
As queer and trans scientists, we face varied systemic barriers to our professional success, resulting in relative absence from faculty ranks at many institutions. In this Perspective, call for a change hiring practices present concrete guidance make it more inclusive process.
While serological and virological evidence documents the exposure of bats to medically-important arboviruses, their role as reservoirs or amplifying hosts is less well-characterized. We describe a novel orbivirus (
Detection of Leptospira interrogans is difficult as a result intermittent leptospiruria and brief leptospiremia. Hence, diagnosis relies heavily on serologic testing, the reference method which microscopic agglutination test (MAT). In horses, clinical leptospirosis has been associated with abortion, recurrent uveitis, sporadic cases hepatic renal disease. Little information exists seroprevalence antibodies to L. in equids United States; past nationwide studies suggest that some areas high...