A5000975757- Random lasers and scattering media
- Advanced Optical Imaging Technologies
- Optical Coherence Tomography Applications
- Advanced Optical Sensing Technologies
- Orbital Angular Momentum in Optics
- Advanced Fluorescence Microscopy Techniques
- Photoacoustic and Ultrasonic Imaging
- Digital Holography and Microscopy
- Social Robot Interaction and HRI
- Engineering Applied Research
- Mechanical Behavior of Composites
- Optical Imaging and Spectroscopy Techniques
- Photorefractive and Nonlinear Optics
- Optical Polarization and Ellipsometry
- Near-Field Optical Microscopy
- Computational Fluid Dynamics and Aerodynamics
- Industrial Vision Systems and Defect Detection
- Optimal Experimental Design Methods
- Metamaterials and Metasurfaces Applications
- Photoreceptor and optogenetics research
- Fatigue and fracture mechanics
- Probabilistic and Robust Engineering Design
- Robotics and Automated Systems
- Structural Load-Bearing Analysis
- Mechanical Engineering and Vibrations Research
Sungkyunkwan University
2025
Korea Advanced Institute of Science and Technology
2013-2024
University of California, Los Angeles
2020-2024
Hyundai Motor Group (South Korea)
2012-2024
Samueli Institute
2022-2024
Korea Aerospace Research Institute
2023
Chungnam National University
2014-2022
University of Illinois Urbana-Champaign
2019-2020
Yonsei University
2016-2020
Hyundai Motors (South Korea)
2019
Abstract 5-Fluorouracil (5-FU) remains the first-line treatment for colorectal cancer (CRC). Although 5-FU initially de-bulks tumor mass, recurrence after chemotherapy is barrier to effective clinical outcomes CRC patients. Here, we demonstrate that p53 promotes WNT3 transcription, leading activation of WNT/β-catenin pathway in Apc Min/+ /Lgr5 EGFP mice, patient-derived organoids (PDTOs) and cells (PDCs). Through this regulation, induces enrichment stem (CSCs) residual tumors, contributing...
We introduce a simple but practical method to measure the optical transmission matrix (TM) of complex media. The TM medium is obtained by modulating wavefront beam impinging on and imaging transmitted full-field speckle intensity patterns. Using retrieved TM, we demonstrate generation linear combination multiple foci demand through medium. This will be used as versatile tool for coherence control waves turbid
Abstract Holographic displays can provide a 3D visual experience to multiple users without requiring special glasses. By precisely tailoring light fields, holographic could resemble realistic scenes with full motion parallax and continuous depth cues. However, available are unable generate such given practical limitations in wavefront modulation. In fact, the limited diffraction angle small number of pixels current modulators derive into scene size narrow viewing angle. We propose flat-panel...
Optical imaging has served as a primary method to collect information about biosystems across scales-from functionalities of tissues morphological structures cells and even at biomolecular levels. However, adequately characterize complex biosystem, an system with number resolvable points, referred space-bandwidth product (SBP), in excess one billion is typically needed. Since gigapixel-scale far exceeds the capacity current optical imagers, compromises must be made obtain either low spatial...
Fluorescence lifetime imaging microscopy (FLIM) is a powerful tool offering molecular specific insights into samples through the measurement of fluorescence decay time, with promising applications in diverse research fields. However, to acquire two-dimensional images, conventional FLIM relies on extensive scanning both spatial and temporal domain, resulting much slower acquisition rates compared intensity-based approaches. This problem further magnified three-dimensional imaging, as it...
The Maxwellian near-eye displays have attracted growing interest in various applications. By using a confined pupil, display presents an all-in-focus image to the viewer where formed on retina is independent of optical power eye. Despite being promising technique, current suffer from limitations such as small eyebox, bulky setup and high cost. To overcome these drawbacks, we present holographic based computational imaging. encoding complex wavefront into amplitude-only signals, can readily...
We evaluate the stress field in and around southern Korean Peninsula with focal mechanism solutions, using data collected from 71 earthquakes (ML = 1.9−5.2) between 1999 2004. For this, hypocentres were relocated well-constrained fault plane solutions obtained set of 1270 clear P-wave polarities 46 SH/P amplitude ratios. The indicate that prevailing faulting types South Korea are strike-slip-dominant-oblique-slip faultings minor reverse-slip component. maximum principal stresses (σ1)...
Light-sheet fluorescence microscopy (LSFM) introduces fast scanning of biological phenomena with deep photon penetration and minimal phototoxicity. This advancement represents a significant shift in 3-D imaging large-scale tissues 4-D (space + time) small live animals. The large data associated LSFM requires efficient acquisition analysis the use artificial intelligence (AI)/machine learning (ML) algorithms. To this end, AI/ML-directed is an emerging area for multi-organ tumor diagnostics....
We introduce a non-invasive approach for optogenetic regulation in biological cells through highly scattering skull tissue using wavefront shaping. The of the incident light was systematically controlled spatial modulator order to overcome multiple light-scattering mouse layer and focus on target cells. demonstrate that illumination with shaped waves enables spatiotemporal intracellular Ca(2+) level at individual-cell level.
We demonstrate that polarization modulation of an illumination beam can effectively control the spatial profile light transmitted through turbid media. Since electric fields are completely mingled in media, states be used to propagation Numerical simulations were performed which agree with experimental results obtained using a commercial in-plane switching liquid-crystal display for modulating input states.
We present measurements of the full Jones matrix individual pixels in a liquid-crystal display (LCD) panel. Employing polarization-sensitive digital holographic microscopy based on Mach-Zehnder interferometry, complex amplitudes light passing through LCD are precisely measured with respect to orthogonal bases polarization states, from which components obtained. also measure changes an applied bias. In addition, optical responses panel arbitrary states incident were characterized matrix.
In this Letter, we present a snapshot hyperspectral light field imaging system using single camera. By integrating an unfocused camera with imager, the image mapping spectrometer, captured five-dimensional (5D) ($x,y,u,v,\lambda $x,y,u,v,λ) ($x,y,$x,y, spatial coordinates; $u,v,$u,v, emittance angles; $\lambda ,$λ, wavelength) datacube in exposure. The corresponding volumetric ($x,y,z$x,y,z) at each wavelength is then computed through scale-depth space transform. We demonstrated advantage of...
We present snapshot hyperspectral light field tomography (Hyper-LIFT), a highly efficient method in recording 5D (x, y, spatial coordinates; θ, φ, angular λ, wavelength) plenoptic function. Using Dove prism array and cylindrical lens array, we simultaneously acquire multi-angled 1D en face projections of the object like those standard sparse-view computed tomography. further disperse measure spectra parallel using 2D image sensor. Within single snapshot, resultant system can capture data...
This paper introduces an emotion interaction system for a service robot. The purpose of systems in robots is to make people feel that the robot not mere machine, but reliable living assistant home. composed recognition, generation, and expression systems. A user's recognized by multi-modality, such as voice, dialogue, touch. robot's generated according psychological theory about emotion: OCC (Ortony, Clore, Collins) model, which focuses on emotional state information environment itself....