A5019545675- Cancer-related molecular mechanisms research
- Genetic and phenotypic traits in livestock
- Titanium Alloys Microstructure and Properties
- Intermetallics and Advanced Alloy Properties
- Advanced ceramic materials synthesis
- Sirtuins and Resveratrol in Medicine
- MXene and MAX Phase Materials
- Genomics and Phylogenetic Studies
- Milk Quality and Mastitis in Dairy Cows
- Adipose Tissue and Metabolism
- Gut microbiota and health
- Epigenetics and DNA Methylation
- Advanced materials and composites
- Animal Genetics and Reproduction
- Molecular Biology Techniques and Applications
- RNA modifications and cancer
- Effects of Environmental Stressors on Livestock
- Genetic and Clinical Aspects of Sex Determination and Chromosomal Abnormalities
- Recycling and utilization of industrial and municipal waste in materials production
- Biochemical effects in animals
- Antioxidant Activity and Oxidative Stress
- Genetic Neurodegenerative Diseases
- Genomics, phytochemicals, and oxidative stress
- Lipid metabolism and disorders
- Graphene and Nanomaterials Applications
Xingtai University
2021-2025
Southern University of Science and Technology
2025
Weichai Power (China)
2024-2025
Institute of Microbiology
2020-2024
Chinese Academy of Sciences
2020-2024
Beijing Jiaotong University
2024
Zhengzhou University
2022-2024
Shandong Academy of Agricultural Sciences
2019-2024
Vrije Universiteit Amsterdam
2022-2024
Wuhan University
2024
The presence or absence of anti-citrullinated peptide antibodies (ACPA) and associated disparities in patients with rheumatoid arthritis (RA) implies disease heterogeneity unknown diverse immunopathological mechanisms. Here we profile CD45+ hematopoietic cells from peripheral blood synovial tissues both ACPA+ ACPA- RA by single-cell RNA sequencing identify subsets immune that contribute to the pathogenesis subtypes. We find several cell abnormalities, including up-regulation CCL13, CCL18...
Sperm motility is the main index used to assess quality of bull semen. It may also be evaluate fertility potential bulls. Protein-coding mRNA and long noncoding RNA (lncRNA) participate in regulation spermatogenesis. Here, we employed strand-specific sequencing profile semen transcriptome (mRNA lncRNA) six paired full-sibling Holstein bulls with divergent sperm determine functions lncRNA motility. Among 20,875 protein-encoding genes detected semen, 19 were differentially expressed between...
Abstract Early‐stage nonalcoholic fatty liver disease (NAFLD) is a silent condition, with most cases going undiagnosed, potentially progressing to cirrhosis and cancer. A non‐invasive cost‐effective detection method for early‐stage NAFLD public health priority but challenging. In this study, an adhesive, soft on‐skin sensor low electrode‐skin contact impedance fabricated. developed synthesize platinum nanoparticles reduced graphene quantum dots onto the reduce by increasing double‐layer...
Light-sheet fluorescence microscopy (LSFM) introduces fast scanning of biological phenomena with deep photon penetration and minimal phototoxicity. This advancement represents a significant shift in 3-D imaging large-scale tissues 4-D (space + time) small live animals. The large data associated LSFM requires efficient acquisition analysis the use artificial intelligence (AI)/machine learning (ML) algorithms. To this end, AI/ML-directed is an emerging area for multi-organ tumor diagnostics....
Neutrophils are the first effectors of inflammatory response triggered by mastitis infection, and important defense cells against pathogenic Escherichia coli (E. coli). DNA methylation, as a critical epigenetic mechanism for regulating gene function, is involved in bovine mastitis.In this study, we sequenced blood neutrophils healthy E. coli-infected mastitic half-sib cows overall methylation levels using transcriptome sequencing reduced representation bisulfite sequencing. The (MCs) were...
Weeds present a significant challenge to high crop yield and quality. In our study, we investigated the phytotoxic activity of β-caryophyllene (BCP) eugenol, which are natural allelopathic chemical compounds, on Arabidopsis seedlings. We found that these compounds inhibited growth thaliana plants. When either BCP or eugenol was applied, it led decrease in content cell wall components such as lignin, cellulose, hemicellulose, pectin; increase levels endogenous hormones like ETH, ABA, SA, JA...
Abstract In this paper, we first reported that porous SiC–Al 2 O 3 ceramics were prepared from solid waste coal ash, activated carbon, and commercial SiC powder by a carbothermal reduction reaction ( CRR ) method under Ar atmosphere. The effects of addition amounts (0, 10, 15, 20 wt%) on the postsintering properties as‐prepared ceramics, such as phase composition, microstructure, apparent porosity, bulk density, pore size distribution, compressive strength, thermal shock resistance,...
Abstract The nutritional value and eating qualities of beef are enhanced when the unsaturated fatty acid content fat is increased. Long-chain acyl-CoA synthetase 1 (ACSL1) plays key roles in transport degradation, as well lipid synthesis. It has been identified a plausible functional positional candidate gene for manipulations composition bovine skeletal muscle. In present study, we determined that ACSL1was highly expressed subcutaneous adipose tissue longissimus thoracis . To elucidate...
Abstract Recycling has enormous economic benefits and practical significance under the context of gradually increasing solid wastes. In order to recycle reuse silicon kerf waste, in this work, porous SiC w /SiC ceramics were successfully prepared by situ synthesis from waste fired at 1400‐1500°C for 4 hours. The results showed that these ceramics, reinforced interlocking whisker, revealed high apparent porosity (48.02%‐51.76%) cold compressive strength (5.68‐9.54 MPa). Furthermore,...
Copy number variations (CNVs) have been demonstrated as crucial substrates for evolution, adaptation and breed formation. Chinese indigenous cattle breeds exhibit a broad geographical distribution diverse environmental adaptability. Here, we analyzed the population structure to high altitude of based on genome-wide CNVs derived from high-density BovineHD SNP array. We successfully detected 318 individuals 24 37 yaks outgroups. A total 5,818 autosomal CNV regions (683 bp-4,477,860 bp in...
In our previous reports, an endophytic bacterium, Bacillus cereus KP120 was isolated from the halophyte species Kosteletzkya virginica. this study, effect of colonization on Arabidopsis thaliana seedlings investigated. Our results showed that inoculation with could promote growth A. plants under salt-stress conditions, compared uninoculated controls. After salt treatment, chlorophyll, proline, activity antioxidant enzymes, Indole-3-acetic acid and 1-aminocyclopropane-1-carboxylate-deaminase...
Abstract Cold climate shapes the genome of animals and drives them to carry sufficient genetic variations adapt changes in temperature. However, limited information is available about genome-wide pattern adaptations cold environments cattle. In present study, we used 777K SNP genotyping (15 Chinese cattle breeds, 198 individuals) whole resequencing data (54 breeds world, 432 disentangle divergent selection signatures, especially between cold-adapted (annual average temperature habitat, 6.24...
Tandem repeats (TR) play important roles in genomic variation and disease risk humans. Long-read sequencing allows for the accurate characterisation of TRs, however, underlying bioinformatics perspectives remain challenging. We present otter TREAT: is a fast targeted local assembler, cross-compatible across different platforms. It integrated TREAT, an end-to-end workflow TR characterisation, visualisation analysis multiple genomes. In comparison with existing tools based on long-read data...
A transvascular interventional photothermal therapy was developed to simultaneously deliver agents while performing laser irradiation via an endovascular route for precision embolization treatment.
<div class="section abstract"><div class="htmlview paragraph">The selection of the key components proton exchange membrane fuel cell (PEMFC) crucially impacts performance. This work developed a model system to simulate power consumption component and temperature dynamic response stack in real systems. A PEMFC simulation was based on AMESim, encompassing air supply subsystem, hydrogen hydrothermal management subsystem. The parameters for flow pressure hydrogen, air, water were...
Using cold isostatic pressing and atmospheric pressure sintering, Ti-18Al-28Nb-xSn alloys were synthesized by incorporating 0.5 at.%, 1 2 4 at.% Sn powder into Ti, Al, Nb powders. This study investigated the effects of concentration on microstructure mechanical properties Ti2AlNb-based alloys, with a particular focus underlying strengthening mechanisms. X-ray diffraction (XRD) analysis identified α2, O, B2 as primary phases in alloy demonstrated that addition significantly influenced...
Recently there has been a wide concern on inorganic nanoparticles as drug delivery carriers. CaCO3 particles have shown promising potential for the development of carriers drugs, but little research had performed regarding their safe dosage maximizing therapeutic activity without harming biosystems. In this study, we assessed biological safety porous spherical microparticles Hela cells. The reactive oxygen species (ROS), glutathione (GSH), carbonyl content in proteins (CCP), DNA-protein...