A5058773729- Neuroendocrine regulation and behavior
- Nitric Oxide and Endothelin Effects
- Electrolyte and hormonal disorders
- Neonatal Respiratory Health Research
- Maternal and fetal healthcare
- Crystallization and Solubility Studies
- X-ray Diffraction in Crystallography
- Cardiac Ischemia and Reperfusion
- Ion Channels and Receptors
- Healthcare Systems and Public Health
- Pregnancy and preeclampsia studies
- Ion channel regulation and function
- Preterm Birth and Chorioamnionitis
- Vitamin C and Antioxidants Research
- Chemical Reaction Mechanisms
- Human Health and Disease
- Neuroscience of respiration and sleep
- Cancer, Stress, Anesthesia, and Immune Response
- Uterine Myomas and Treatments
- Inflammation biomarkers and pathways
- Social Issues in Poland
- Enhanced Recovery After Surgery
- Ovarian function and disorders
- Cardiac Arrhythmias and Treatments
- Retinopathy of Prematurity Studies
Medical University of Białystok
2015-2025
Warsaw University of Technology
2022
Abstract Background Quercetin has recently become a remarkably popular subject of research due to its broad beneficial pharmacological properties. The goal our study was observe effects on contractility human gastric smooth muscles in reference the NO pathway and direct influence potassium channels. Methods Tissues were obtained from patients undergoing sleeve gastrectomy morbid obesity (n = 10 aged 24–56; BMI 47.16 ± 1.84). following parameters evaluated recordings: area under curve (AUC),...
There is now considerable evidence for the involvement of K+ channels in nitric oxide (NO) induced relaxation smooth muscles including myometrium. In order to assess whether apamin-sensitive play a role NO - human uterus, we have studied effect specific blockers these on myometrium from non-pregnant women. vitro isometric contractions were recorded uterine tissues premenopausal women who had undergone hysterectomy. Apamin (10 nM) and scyllatoxin did not alter spontaneous myometrial...
Phloroglucinol (PHG), an analgesic and spasmolytic drug, shows promise in preventing high-fat-diet (HFD)-induced non-alcoholic fatty liver disease (NAFLD) insulin resistance. In Wistar rats, 10 weeks of PHG treatment did not prevent HFD-induced weight gain but significantly mitigated fasting hyperglycemia, impaired responses, steatosis. This protective effect was linked to hepatic lipogenesis or AMP-activated protein kinase (AMPK) activation. Instead, improved mitochondrial function by...
We aimed to prospectively examine β-adrenoceptor-mediated uterine contractility in women suffering from gynecological malignancies. Myometrial specimens were obtained non-pregnant undergoing hysterectomy for benign disorders, and ovarian, endometrial, synchronous ovarian–endometrial, cervical cancer. Contractions of myometrial strips an organ bath before after cumulative dosages β2- β3-adrenoceptor agonists with preincubation propranolol, SR 59230A, butoxamine studied. All induced a...
Resveratrol, as a polyphenolic compound that can be isolated from plants, and also component of red wine has broad beneficial pharmacological properties. The aim was to investigate the role nitric oxide potassium channels in resveratrol-induced relaxation human gastric smooth muscle. Gastric tissues were obtained patients who underwent sleeve gastrectomy for severe obesity (n = 10 aged 21-48; BMI 48.21 ± 1.14). mechanical activity muscle strips detected under isometric conditions response...
The aim of the present study was to examine how, under in vitro conditions, human left internal thoracic artery (LITA) reacts contractile agonist:potassium chloride (KCL) as a function time, well whether change LITA reactivity can correlate with occurrence refractory vascular spasm (RVS). Distal segments obtained from 33 patients aged 38-73, at time routine coronary surgical revascularization (CABG). Contractile response 80 mmol K(+) recorded isometric conditions. In 16 (48,5 %) segments,...
The aim of the study was to compare perception stress and characteristic coping-strategies among students in context different anti-pandemic measures taken Belarus, Poland, Russian exclave Kaliningrad. A cross-sectional online survey using standardized questionnaires (Perceived Stress Scale-PSS-10 Brief-COPE-Mini-COPE inventory) conducted 3113 seven universities three neighboring regions on both sides eastern border EU. groups that are most prone Polish Russians students. Among from 122...
Immunohistochemical localization and distribution of endothelin (ET-1) nitric oxide synthase (eNOS) were investigated in precollector collector lymphangions lymphatic vessels leaving the ovary found vascular subovarian plexus (mesovarium) as well those emanating from oviductal isthmus uterine horn (mesosalpinx mesometrium, respectively) forming paraovarian broad ligament uterus during different phases estrous cycle pigs. The polyclonal antibody for ET-1 monoclonal eNOS isoform used studies...
The aim was the evaluation of IL-6 concentration in peritoneal lavage fluid children which underwent cholecystectomy to ascertain if there is a difference early inflammatory response depending on type surgical approach (open vs. laparoscopy). analysis high-mobility group protein B1 (HMGB1) and heat shock 70 (HSP70) performed find out source related tissue damage. samples, obtained at beginning end laparoscopic (<mml:math xmlns:mml="http://www.w3.org/1998/Math/MathML"...
Abstract Background Extragonadal follicle-stimulating hormone receptor (FSHR) expression at low levels has been shown in several normal and tumor tissues, including myometrium adipose tissue. FSH-FSHR signaling the suggested to regulate uterine contractile activity timing of labor. In contrast, linked activation brown/beige fat thermogenesis The issue extragonadal FSHR its functionality remains contentious within scientific community, as contradictory findings necessitate further independent...
The authors developed a method of measuring the fractal box dimension human eyeball movement. They found property in schizophrenic subjects (n=10) and normal controls (n=10). value for patients differs from results obtained control group.