A5047267620- Head and Neck Cancer Studies
- Thyroid Cancer Diagnosis and Treatment
- Reconstructive Surgery and Microvascular Techniques
- Thyroid and Parathyroid Surgery
- Salivary Gland Tumors Diagnosis and Treatment
- Tracheal and airway disorders
- Sinusitis and nasal conditions
- Head and Neck Surgical Oncology
- Ear and Head Tumors
- Cannabis and Cannabinoid Research
- Reconstructive Facial Surgery Techniques
- Parathyroid Disorders and Treatments
- Nasal Surgery and Airway Studies
- Esophageal Cancer Research and Treatment
- Meta-analysis and systematic reviews
- Statistical Methods in Clinical Trials
- Smoking Behavior and Cessation
- Head and Neck Anomalies
- Global Cancer Incidence and Screening
- Homelessness and Social Issues
- Radiology practices and education
- Clinical Laboratory Practices and Quality Control
- Radiation Dose and Imaging
- Voice and Speech Disorders
- Cancer Risks and Factors
McMaster University
2015-2025
Abbott (Canada)
2024
Abbott (United States)
2024
Western University
2021
University of British Columbia
2020
Hamilton Health Sciences
2020
University of Toronto
2020
Juravinski Hospital
2018
St. Joseph’s Healthcare Hamilton
2015-2017
Charlottesville Medical Research
2017
Abstract Background Patients with human papillomavirus-positive (HPV+) oropharyngeal squamous cell carcinoma (OPC) have substantially better treatment response and overall survival (OS) than patients HPV-negative disease. Treatment options for HPV+ OPC can involve either a primary radiotherapy (RT) approach (± concomitant chemotherapy) or surgical adjuvant radiation) transoral surgery (TOS). These two paradigms different spectrums of toxicity. The goals this study are to assess the OS...
Background Aspirin‐exacerbated respiratory disease (AERD) is a clinical triad consisting of aspirin/acetylsalicylic acid (ASA) sensitivity, bronchial asthma, and nasal polyposis. Although reactions following ingestion ASA other nonsteroidal anti‐inflammatory drugs (NSAIDs) are considered hallmark the condition, inflammation persists despite patients’ avoidance NSAIDs. Treatment this condition remains challenging includes both medical surgical options. Methods A prospective crossover...
Abstract Background Advanced head and neck malignancies with underlying bony involvement often require aggressive oncological resection of large segments the oral cavity including mandible. These patients vascularized donor osseous free tissue transfer to reconstruct significant defects. Traditionally, bone is harvested on its vascular supply shaped defect in a hand fashion (FHS). However, virtual surgical planning (VSP) has emerged as method optimize reconstructive outcomes decrease...
Background Cutaneous head and neck melanoma (cHNM) has a high rate of false-negative sentinel lymph node biopsy (SLNB) up to 25% risk recurrence despite negative SLNB. The aim this study was investigate the pattern in patients with cHNM Methods A retrospective cohort consecutive at tertiary care centre from 2014-2022. We included all All were categorized into Breslow thickness >2 mm ≤2 extracted information pertaining histopathological characteristics presence type disease recurrences....
Cannabis sativa, the most widely used illicit substance in Canada, has a unique ability to facilitate relaxation and relieve anxiety while reducing pain. However, no study date examined quality of life (QOL) psychosocial issues relation use this drug among patients with newly diagnosed head neck cancer (HNC).To examine differences QOL outcomes between marijuana users nonusers HNC.This prospective cohort was conducted at tertiary care center. Patients were enrolled consecutively prospectively...
Objective Aspirin exacerbated respiratory disease (AERD) is comprised of aspirin/acetylsalicylic acid (ASA) sensitivity, bronchial asthma, and nasal polyposis. Treatment this condition challenging may include topical/systemic steroids, endoscopic sinus surgery, and/or aspirin desensitization. Study Design A prospective crossover pilot study (n = 10) was conducted in which patients were randomized into either 2 groups with 6 weeks regular diet (R) or a low salicylate (LS). Setting The...
Commercial assays measuring HPV E6 viral oncoproteins, E6/E7 mRNA or DNA were used to test neck lymph node fine needle aspirates (FNA) and oropharyngeal samples (saliva oral swabs) from 59 Canadian patients with squamous cell carcinomas (OPSCC). Overall agreements of p16 antigen staining tumors FNA tested for OncoE6™, Aptima cobas 81.4% (k 0.53), 94.9% 0.83) 91.1% 0.73) respectively. Using presence in a subset 25 as the comparator, overall agreement was 64.0% 0.08) 88.0% 0.65) 91.7% 0.70)...
Background Cholesteatoma is a destructive, erosive growth of keratinizing squamous epithelium in the middle ear cleft. Following treatment with canal wall-up (CWU) tympanomastoidectomy, surveillance residual and recurrent disease has traditionally been achieved through second look tympanotomy following initial procedure. Historically, MRI sequences have inadequate at differentiating between granulation tissue, inflammation, cholesteatoma. Recent literature shown diffusion-weighted magnetic...
Background: Despite universal healthcare in Canada, low socioeconomic status (SES) has been associated with worse survival oral cavity squamous cell carcinoma (OCSCC) patients. However, the relationship between SES and outcomes during acute postoperative period is poorly defined. Hamilton, Ontario, presents a unique population widely varying within same geography. The objective of this study was to examine SES, length hospital stay (LOHS), complications OCSCC. Methods: Newly diagnosed OCSCC...
This study aims to understand the attitudes toward marijuana in HNC patients.A 17-question questionnaire regarding medical (MM) was distributed patients at a tertiary cancer center.63 completed questionnaire. Patients that had used or were using described benefit with symptoms of headache, pain, nausea, and loss appetite. 83% all considered as treatment for related pain 67% anxiety. About 70% actively undergoing believed medications would help during treatment.By understanding how perceive...