A5058399015- Blood Pressure and Hypertension Studies
- Heart Rate Variability and Autonomic Control
- Cardiovascular Disease and Adiposity
- Cardiovascular Health and Disease Prevention
- Hemodynamic Monitoring and Therapy
- Hormonal Regulation and Hypertension
- Obstructive Sleep Apnea Research
- Cardiovascular and exercise physiology
- Cardiovascular Function and Risk Factors
- Sodium Intake and Health
- Cardiovascular Effects of Exercise
- Oral microbiology and periodontitis research
- Cardiac Imaging and Diagnostics
- Liver Disease Diagnosis and Treatment
- Cardiovascular Syncope and Autonomic Disorders
- Heart Failure Treatment and Management
- Cardiac electrophysiology and arrhythmias
- Cardiomyopathy and Myosin Studies
- Renal and Vascular Pathologies
- Nutritional Studies and Diet
- Advanced Glycation End Products research
- Cardiac Arrhythmias and Treatments
- Neuroscience of respiration and sleep
- Biomarkers in Disease Mechanisms
- Lipoproteins and Cardiovascular Health
National and Kapodistrian University of Athens
2016-2025
Hippocration General Hospital
2015-2025
St George's, University of London
2020-2024
St George’s University Hospitals NHS Foundation Trust
2022-2023
Guy's and St Thomas' NHS Foundation Trust
2022-2023
Harefield Hospital
2022-2023
St George's Hospital
2023
Royal Brompton Hospital
2022
Georgetown University Medical Center
2014-2016
Georgetown University
2014-2016
Hypertension constitutes a major risk factor for heart failure with preserved ejection fraction (HFpEF). HFpEF is prevalent clinical syndrome increased cardiovascular morbidity and mortality. Specific guideline-directed medical therapy (GDMT) not established due to lack of positive outcome data from randomized controlled trials (RCTs) limitations available studies. Although evidence limited, control blood pressure (BP) widely regarded as central the prevention care in HFpEF. Thus, current...
Background Takotsubo Syndrome (TTS) is an increasingly recognized condition, initially perceived as benign, but now associated with considerable morbidity and mortality. Its pathophysiology remains elusive despite advancements in understanding, management strategies remain inconsistent lack support from randomized clinical trials. Aims This review aims to consolidate current evidence on the pathophysiology, diagnostic algorithms, treatment approaches, prognosis of TTS, while highlighting...
Little is known regarding the clinical course and prognosis of resistant hypertension (RHT). We evaluated predictors persistent RHT associated cardiovascular risk.We studied 1911 treated hypertensive patients (aged 59±11 years, 49% men) for a mean period 3.9 years. At baseline, data were collected underwent echocardiographic measurements, routine blood testing additional workup exclusion secondary causes (office-based uncontrolled under at least three drugs including diuretic or controlled...
A significant proportion of hypertensive patients are both smokers and obese. Several pathophysiological mechanisms involved in the combined effect smoking obesity on hypertension onset maintenance. These include increased sympathetic nervous system activity, endothelial dysfunction, inflammation, oxidative stress, insulin resistance. The presence these major cardiovascular risk factors may lead to difficult-to-control as well substantially increase for an adverse outcome. It is, therefore,...
Background Cardiomyopathies are a significant cause of heart failure, arrhythmia and cardiac morbidity in the general population/ Cardiovascular magnetic resonance (CMR) is valuable tool for diagnostic work-up patients with acute events. Objectives: This study evaluated value CMR yield cardiomyopathies hospitalized presentation. Methods A retrospective analysis was conducted 535 consecutive who underwent at Hippokration Hospital, Athens, Greece, to identify subset scans performed an urgent...
Background: Cardiomyopathies are a significant cause of heart failure, arrhythmia, and cardiac morbidity in the general population. Cardiovascular magnetic resonance (CMR) is valuable tool for diagnostic work-up patients with acute events. Objectives: This study evaluated value CMR yield cardiomyopathies hospitalized presentation. Methods: A retrospective analysis was conducted 535 consecutive who underwent at Hippokration Hospital, Athens, Greece, to identify subset scans performed on an...
Objective: Beneficial effects of continuous positive airway pressure (CPAP) on both blood (BP) levels and variability have been documented in patients with obstructive sleep apnoea (OSA). We investigated the relevant impact different dosing times antihypertensive drugs beyond CPAP application. Methods: In this prospective, cross-over trial, we included 41 newly diagnosed hypertension never treated OSA (apnoea-hypopnea index ≥15/h), without increased daytime somnolence (Epworth Score ≤10...
This study aimed to investigate the effects of renal denervation (RDN) on sympathetic nerve activity and insulin resistance in patients with metabolic syndrome.Seventeen fulfilled at least four five criteria for syndrome under stable use two antihypertensive drugs were randomized 3 : 1 ratio RDN (n = 13, 12 men, age: 58 ± 7 years) control groups 4, three 60 5 followed up months. Muscle (MSNA) rest during standard 75 g oral glucose tolerance test (OGTT) was assessed.In group, office average...
Several studies have reported a small yet significant decrease in blood pressure (BP) with continuous positive airway (CPAP) application patients obstructive sleep apnea (OSA). We investigated the long-term efficiency of CPAP management hypertensive OSA on top conventional antihypertensive medication.We followed 91 nonsleepy (aged 54 ± 9 years, 69 men) essential hypertension and newly diagnosed moderate-to-severe (apnea-hypopnea index, 38 24 events/h polysomnography) for mean period 3.1...