The purpose of this study was to conduct a preliminary assess knowledge, attitude, and practice (KAP) associated with antibiotic use among medical students (MS) non-medical (NMS) at Kathmandu University, Nepal. A self-administered questionnaire distributed 1223 for cross-sectional study. In total, 1222 questionnaires collected from 609 MS 613 NMS were regarded as effective. t-test Chi-square test applied analyze the data. total 25 out 39 questions in KAP survey found have statistical...

Microorganisms with antimicrobial resistance (AMR) are prevalent among humans and animals, also found in the environment. Though organisms AMR can spread to via food from animal sources, burden of food-producing animals remains largely unknown. Thus, we assessed pattern Escherichia coli isolated chicken cecum samples explored issues contributing Dhulikhel Municipality Nepal. We conducted a mixed-methods study, comprising cross-sectional quantitative component, collection cecal slaughter...

The construction industry in Nepal, which employs a significant proportion of the population, ranks as one largest industries country. Construction work is physically demanding and can be risky due to use heavy machinery presence intense physical labor. However, mental health workers Nepal often neglected. This study aimed assess psychological distress (depression, anxiety, stress symptoms) its association with socio-demographic, lifestyle, occupational factors among Kavre district, Nepal.We...

Evidence-based decision-making to combat antimicrobial resistance (AMR) mandates a well-built community-based surveillance system for assessing patterns among commensals and pathogenic organisms. As there is no such in Nepal, we attempted describe the pattern E. coli isolated from fecal samples of apparently healthy individuals Dhulikhel municipality also explored local drivers AMR. We used mixed-method design with cross-sectional quantitative component descriptive qualitative component,...

To describe antibiotic prescription patterns in the emergency department (ED) of a tertiary healthcare center Nepal.

Pharmaceutical companies actively advertise their branded antibiotics, which influence sales at community pharmacies. The major proportion of out pocket health spending is on medicine; and affordability antibiotics has always been a crucial issue in most developing countries. This study identified promotional activities adopted by pharmaceutical pharmacies medicine shops the selected to clients with lowest wages Kavrepalanchok district Nepal.A cross-sectional was conducted among all (n = 34)...

The misuse of pesticides among farmworkers in Nepal is commonplace. To address this, we implemented a pilot educational intervention (three modules delivered over 3 days and lasting approximately h each) Kavre District Nepal. Modules included: (i) health environmental effects pesticides, (ii) use personal protective equipment, (iii) label literacy behavioral factors that influence pesticide exposure. In addition, 10 posters with key messages from each the were hung throughout...

Healthcare-associated infections (HAIs) and antimicrobial resistance (AMR) have posed major challenges to South Asia. The purpose of this study is explore the direct medical economic burden attributable HAIs AMR in Nepal.A prospective was conducted a teaching hospital Nepal from 16 December 2017 April 2018. demographic, clinical, financial expense data were extracted records, laboratory reports, information system. STATA 12.0 used conduct descriptive analysis, χ2 test, t propensity score...

A referral hospital in Kavre, Nepal.To assess 1) compliance with National Antibiotic Treatment Guidelines (NATG), specifically, whether the administration of surgical antibiotic prophylaxis (SAP) (initial dosing and redosing) was NATG for patients who were not eligible, 2) development site infections (SSIs) among underwent surgery Department General Surgery (July-December 2019).This a retrospective cohort analysis.The analysis included 846 patients, which 717 (85%) eligible SAP 129 (15%)...

Background Helicobacter pylori is one of the most prevalent infectious disease worldwide. The treatment regimens involve mainly two therapies: Standard Triple drug therapy and Sequential therapy. Several studies have shown that sequential has higher eradication rates H. than standard triple since proper study on still lacking in Nepal, this attempted to compare efficacy Drug Therapy gastritis with respect 
 Objective To investigate Antigen Stool test. Method This was prospective...

Individuals' perceived fairness or justice beliefs are related to health in numerous ways. However, environment research date has given little attention of environmental exposures as experienced by individuals. This study explored the feasibility a bottom-up digital participatory (via mobile phones) approach using ecological momentary assessment (EMA) capture individuals' subjective experience and evaluation those affected context Nepal. In total, 22 individuals participated for 28 days. The...

Introduction: Globally, burnout on healthcare workers leads to negative impact the individual and organizational levels, which ultimately affects patient care. This study aims identify prevalence, contributing factors, mitigation of among during Covid-19 pandemic. Method: is a web-based cross-sectional conducted 177 pandemic in Dhulikhel Hospital, Kathmandu University Nepal, from June December 2021. The participants were selected using convenience sampling technique. Copenhagen Burnout...

As one of the poorest nations, citizens Nepal lack access to safe, affordable, and sufficient drinking water. While many nationwide studies have been performed at a country or regional level in determine regions highest vulnerability, this study uniquely recognizes economic heterogeneity within single rural village assesses impact household socioeconomic status on water intracommunity level. Household surveys setting provided information for locally-informed relative wealth index. A spatial...

Designated as a "priority disease" by World Health Organization, Osteoarthritis is the most common chronic rheumatic disease. Providing proper treatment for still major public health challenge. Diacerein has been proposed slow acting, symptom modifying or even disease drug used in having risk-benefit ratio far better than conventionally drugs. However, evidence of efficacy and safety use yet to be explored. Hence, this study attempted investigate management knee osteoarthritis.This an...

Background Hormonal contraceptives are one of the most commonly used means contraception. Lack contraception may lead to large family size, increased preexisting illness on pregnancy, social and economic instability, risk unsafe abortion so on. This also unintended pregnancies which alter outcomes as well. However, improper uses associated with several serious adverse effects. Therefore, achieve optimum benefit least effects, safe effective use these agents monitoring their pattern patient...

SETTING: Dhulikhel Hospital, Kathmandu University Kathmandu, Nepal. OBJECTIVES: 1) To report the incidence of health-care-associated infections (HAIs), 2) to compare demographic, clinical characteristics and hospital outcomes in those with without HAIs; 3) verify bacterial types HAI community-acquired (CAIs) among inpatients invasive devices and/or surgical procedures. DESIGN: This was a cohort study using secondary data (December 2017 April 2018). RESULTS: Of 1,310 inpatients, 908 (69.3%)...

(1) Background: Surgical antibiotic prophylaxis (SAP) is important for reducing surgical site infections. The development of a dedicated hospital SAP guideline in the Dhulikhel Hospital was recommendation from baseline study on compliance. Compliance with this new enhanced through establishment committee, an stewardship program and funding training healthcare professionals. Using follow-up after introducing guidelines, we compared: (a) overall compliance guidelines (b) proportion eligible...

Introduction: The mainstay treatment according to the Global Initiative for Chronic Obstructive Lung Disease 2023 guidelines Pulmonary is combination of long acting bronchodilators with addition inhaled corticosteroids only in patients increased exacerbations and an eosinophil count ≥ 300 cells/μL. Despite recommendations, are most commonly overprescribed. So, this study aims follow mild moderate cases disease who currently on therapy clinical efficacy after its withdrawal. Methods: was a...

Background Antimicrobials agents are the most widely and often imprudently used therapeutic drugs globally. The pediatric population comprises 20-25% of total world population, various acute chronic diseases prone to this group. It is also estimated that 50% 85% children prescribed with antimicrobials in developed developing countries. misuse not only contributes development antimicrobial resistance but results economic burden on health care system.
 Objective To analyze usage its cost...

Abstract Background: Healthcare-associated infections (HAIs) and antimicrobial resistance (AMR) have been becoming the public global health issues. The purpose of this study is to estimate direct economic burden attributable HAIs AMR. Methods: This applied propensity score matching (PSM) methodology conduct a prospective case-control disease AMR 16 th December, 2017 April, 2018 in teaching hospital Nepal. Clinical information was retrieved from Hospital Health Information electronic medical...

Community pharmacies are the most accessible healthcare providers l which plays a key role in primary services managing minor ailment and ensure quality use of drugs. Our study aimed to assess care from community using unannounced standardized patient.All three municipalities Kavrepalanchowk district were visited by patients presenting with acute dysentery, seasonal influenza, gastritis, diarrhea pulmonary tuberculosis. Responses audio-recorded checked standard checklist. Descriptive...

Background Community pharmacists are the primary contact point in a healthcare system who provide medication information to patients and enable them make appropriate decision regarding their therapy. Hence, this study explored patients' perception of community pharmacist based on counseling. Objective To patient's counseling by at Manohara Municipality, Kathmandu, Nepal Method A cross sectional was conducted from November 2020 April 2021 population visiting pharmacies Kageshwori Municipality...