Linzhu Ren

ORCID: 0000-0002-1092-6435
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About
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Research Areas
  • Animal Virus Infections Studies
  • Viral gastroenteritis research and epidemiology
  • Virus-based gene therapy research
  • Viral Infections and Immunology Research
  • Animal Disease Management and Epidemiology
  • SARS-CoV-2 and COVID-19 Research
  • interferon and immune responses
  • Viral Infections and Vectors
  • Viral Infectious Diseases and Gene Expression in Insects
  • Vector-Borne Animal Diseases
  • CRISPR and Genetic Engineering
  • Extracellular vesicles in disease
  • Plant Virus Research Studies
  • Herpesvirus Infections and Treatments
  • Mosquito-borne diseases and control
  • Escherichia coli research studies
  • Vector-borne infectious diseases
  • Influenza Virus Research Studies
  • Bacteriophages and microbial interactions
  • MicroRNA in disease regulation
  • Rabies epidemiology and control
  • Virology and Viral Diseases
  • Toxin Mechanisms and Immunotoxins
  • COVID-19 Clinical Research Studies
  • RNA Interference and Gene Delivery

Jilin University
2016-2025

Yunnan Agricultural University
2024

Inner Mongolia University for Nationalities
2024

National University of Mongolia
2024

Yangtze University
2024

Shandong Normal University
2019

Jilin Province Science and Technology Department
2018

Jilin Medical University
2010-2015

Baotou Medical College
2008

IBM (United States)
2007

Porcine circovirus 4 (PCV4) is a newly identified porcine in pigs, belonging to the Circoviridae family Circovirus genus. The virus was detected all age groups and aborted foetuses. However, has not been isolated from field samples date. In this study, PCV4 successfully rescued an infectious clone. replicable PK-15 cells piglets, which can be almost collected of challenge groups. No obvious clinical symptoms were observed both sham- PCV4-inoculated piglets during whole experiment. visible...

10.1111/tbed.14498 article EN Transboundary and Emerging Diseases 2022-03-03

Porcine circovirus 2 (PCV2) and pseudorabies virus (PRV) are economically important pathogens in swine. PCV2 PRV coinfection can cause more severe neurological respiratory symptoms higher mortality of piglets. However, the exact mechanism involved its pathogenesis remain unknown. Here, porcine kidney cells (PK-15) were infected with and/or PRV, then activation immune inflammatory pathways was evaluated to clarify influence on responses. We found that promote nuclear factor-κB (NF-κB), c-Jun...

10.3390/ijms23084469 article EN International Journal of Molecular Sciences 2022-04-18

Porcine circovirus type 4 (PCV4) is a newly identified porcine (PCV) belonging to the Circovirus genus Circoviridae family. Although several groups have conducted epidemiological investigations on PCV4 and found that also exists widely in pigs, there are few reports origin evolution of PCV4. In this study, genetic relationship between PCV4, mink (MiCV), bat (BtCV), PCV1, PCV2, PCV3 was analyzed, consistency viral proteins three-dimensional (3D) structure epitopes predicted. We genome protein...

10.3390/ijms23063288 article EN International Journal of Molecular Sciences 2022-03-18
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