A5082922736- Animal Virus Infections Studies
- Viral gastroenteritis research and epidemiology
- Virus-based gene therapy research
- Meat and Animal Product Quality
- Viral Infections and Immunology Research
- Proteins in Food Systems
- Hepatitis B Virus Studies
- Probiotics and Fermented Foods
- Metabolomics and Mass Spectrometry Studies
- Microencapsulation and Drying Processes
- Cancer Research and Treatments
- Fatty Acid Research and Health
- Advanced Chemical Sensor Technologies
- Glycosylation and Glycoproteins Research
- Liver Disease Diagnosis and Treatment
- Polysaccharides and Plant Cell Walls
- Monoclonal and Polyclonal Antibodies Research
- Adipose Tissue and Metabolism
- Polysaccharides Composition and Applications
- Food Drying and Modeling
- Cell death mechanisms and regulation
- Antimicrobial agents and applications
- Tissue Engineering and Regenerative Medicine
- Food composition and properties
- Medical Device Sterilization and Disinfection
Shanghai Academy of Agricultural Sciences
2025
Tibet University
2018-2024
Jilin University
2022-2023
China Animal Disease Control Center
2018-2023
Peking University
2021
China Agricultural University
2021
Beijing Jishuitan Hospital
2021
Panzhihua Central Hospital
2020
Jingning County People's Hospital
2014
Third Affiliated Hospital of Sun Yat-sen University
2012
Porcine circovirus 4 (PCV4) is a newly identified porcine in pigs, belonging to the Circoviridae family Circovirus genus. The virus was detected all age groups and aborted foetuses. However, has not been isolated from field samples date. In this study, PCV4 successfully rescued an infectious clone. replicable PK-15 cells piglets, which can be almost collected of challenge groups. No obvious clinical symptoms were observed both sham- PCV4-inoculated piglets during whole experiment. visible...
Porcine circovirus 2 (PCV2) and pseudorabies virus (PRV) are economically important pathogens in swine. PCV2 PRV coinfection can cause more severe neurological respiratory symptoms higher mortality of piglets. However, the exact mechanism involved its pathogenesis remain unknown. Here, porcine kidney cells (PK-15) were infected with and/or PRV, then activation immune inflammatory pathways was evaluated to clarify influence on responses. We found that promote nuclear factor-κB (NF-κB), c-Jun...
Volvariella volvacea was grown on cottonseed hull waste compost and divided into high-yield (HBE) low-yield (LBE) conditions. Gene sequencing used to examine bacterial fungal populations during husk composting. At the end of fermentation, dominant genera in HBE were Chelatococcus Thermobacillus, while Symbiobacterium Acinetobacter more abundant LBE compost. Ascomycota Basidiomycota dominated all composting phases. The Colletotrichum, Pichia, Mycothermus, Thermomyces phase II had higher...
LHEPS-1 exhibited the strongest anti-proliferation effect, prevented G<sub>1</sub> to S transition and increased apoptosis of human colon cancer HT-29 cells.
Porcine circovirus 2 (PCV2) and pseudorabies virus (PRV) are two important pathogens in the pig industry. PCV2 or PRV infection can induce endoplasmic reticulum stress (ERS) unfolded protein response (UPR). However, effect of coinfection on ERS UPR pathways remains unclear. In this study, we found that inhibited proliferation mainly at 36 to 72 hpi, while enhanced middle stage infection. Notably, is main factor during coinfection. The results transcriptomic analysis showed with activated...
In this study, the differences in protein profiles between livers of Shannan Tibetan pigs (SNT), Linzhi (LZT) and Jiuzhaigou (JZT) were comparatively analyzed by tandem mass spectrometry-labeling quantitative proteomics. A total 6804 proteins identified: 6471 quantified 1095 screened as differentially expressed (DEPs). Bioinformatics analysis results show that, compared with JZT livers, up-regulated DEPs SNT LZT mainly promoted hepatic detoxification through steroid hormone biosynthesis...
Drying is an important preservation method of casein. Traditional natural draining and drying processes have low efficiency, long processing time, poor product quality, which urgently need to be improved. This study investigated the effects pre-dehydration intensities (30 N 30 min (PreD1) 50 (PreD2)) methods (including pulsed vacuum (PVD), infrared (IRD), hot air (HAD)) on kinetics, modeling, quality yak milk These findings reveal that PreD2 PVD both had a positive impact shortening time....
In recent years, Tibetan pig breeding and meat processing have developed rapidly. However, the basic physiological biochemical characteristics of pork not been systematically explored. The present study conducted a high-throughput analysis tenderloin (longissimus dorsi) proteome pigs performed functional annotation bioinformatics identified proteins. Based on offline two-dimensional liquid chromatography fractionation MS/MS identification, total 1,723 proteins were in pigs. Gene ontology...
Introduction Echinococcosis can incur substantial economic losses for the livestock industry by causing organ condemnation, delayed growth, and reduced meat wool output quality in sheep cattle, as well increased surgery costs, hospital care, decreased productivity humans. Yet echinococcosis could be prevented controlled interventions, such dog management deworming, lamb vaccination, slaughter management, training public education. Methods Exploiting temporal spatial variations number of...
Tripartite motif protein 21 (TRIM21) is an interferon-inducible E3 ligase, containing one RING finger domain, B-box motif, coiled-coil domain at the N-terminal, as well PRY and SPRY C-terminal. TRIM21 expressed in many tissues plays important role systemic autoimmunity. However, different roles virus infections. In this study, we evaluate relationship between porcine PCV2 infection host immune responses. We found that modulated expression of TRIM21. can enhance interferons proinflammatory...
The emerging porcine circovirus type 3 (PCV3) has been reported in Chinese swine herds since 2017. We performed a nationwide investigation on the prevalence of PCV3 pig breeding farms and slaughterhouses China. A total 4,040 tonsil samples were collected from 89 25 provinces, 1,419 lymph node 50 27 provinces. PCR results showed that farms, positive rate was 41.6% (37/89) at farm level 5.0% (201/4040) individual level. In slaughterhouses, 62.0% (31/50) 8.0% (114/1419) PCR-positive further...
In this study, the content of vitamins and toxic beneficial (macro- micro-) minerals in milk from yaks raised at different altitudes (3,215, 4,340, 5,410 m) was investigated. For comparison, components cow's were also measured. At higher altitudes, a significant (P < 0.05) increase vitamin A E observed yak's milk, whereas opposite for B1 B2. No statistical difference C, Ca, P, Na, K, Mg concentrations altitudes. The Zn showed no difference, Mn Fe 3,215 m lower than those Pb Cd did not exceed...
BACKGROUND In this study, recent trends in the distribution and drug resistance of pathogenic bacteria isolated from patients treated at a burn ward between 2006 2019 were investigated. AIM To develop more effective clinical strategies techniques for prevention treatment bacterial infections patients. METHODS Clinical samples with positive collected Beijing Jishuitan Hospital China January December 2019. The retrospectively analyzed, was determined, changes during different period assessed....
Porcine epidemic viruses, such as pseudorabies virus (PRV) and porcine circovirus 2 (PCV2), are among the most economically damaging pathogens affecting swine industry. Importantly, previous studies have shown that cases of human infection with PRV occur frequently, indicating considerable risk transmission from pigs to humans. Zinc finger CCCH-type containing 11A (ZC3H11A) has been confirmed play a crucial role in maintaining nuclear export mRNA under stress humans, but its remains unknown....
Porcine circovirus disease (PCVD) caused by porcine type 2 (PCV2) is widely distributed in pig farms. Up until now, nine genotypes of PCV2, PCV2a to 2i, have been identified diseased pigs worldwide. This study analyzed 302 samples collected the Jilin Province China from 2016 2021, followed genetic analysis PCV2 isolates. Meanwhile, antigen epitopes, amino acid mutations, 3D structure isolates and commercially available vaccine strains were evaluated compared. The results showed that...