A5103084487- Protein Hydrolysis and Bioactive Peptides
- Meat and Animal Product Quality
- Visual perception and processing mechanisms
- Probiotics and Fermented Foods
- Computational Drug Discovery Methods
- Microbial Metabolites in Food Biotechnology
- Ziziphus Jujuba Studies and Applications
- Polysaccharides and Plant Cell Walls
- Action Observation and Synchronization
- Polyamine Metabolism and Applications
- Food Allergy and Anaphylaxis Research
- Food Quality and Safety Studies
- Neurological Disease Mechanisms and Treatments
- Bioinformatics and Genomic Networks
- Protein Structure and Dynamics
- Proteins in Food Systems
- Face Recognition and Perception
- Neural dynamics and brain function
- Neural and Behavioral Psychology Studies
- Neural Networks and Applications
- Cancer-related molecular mechanisms research
- Polysaccharides Composition and Applications
- Ocular and Laser Science Research
- Microbial Natural Products and Biosynthesis
- Sulfur Compounds in Biology
Tarim University
2011-2023
China Pharmaceutical University
2022-2023
Dali University
2023
University of Chinese Academy of Sciences
2012-2022
Institute of Psychology, Chinese Academy of Sciences
2016-2022
Chinese Academy of Sciences
2013-2022
Center for Excellence in Brain Science and Intelligence Technology
2016-2022
Shenyang Medical College
2021-2022
Chinese Institute for Brain Research
2021-2022
Sichuan University
2021
Due to the presence of pores and low density, a high recoverable energy density (Wrec) value is usually obtained at cost storage efficiency (η) in lead-free potassium sodium niobate [(K, Na)NbO3, KNN] based ceramics, which also affects hardness finally limiting further development practical applications. A Wrec (∼3.60 J/cm3 ) η (∼74.2%) are 0.975K0.5Na0.5NbO3-0.025LaBiO3 (0.975KNN-0.025LB) ceramics simultaneously under dielectric breakdown strength (DBS) 340 kV/cm, together with fast...
Abstract Radiation‐induced lung injury (RILI) mainly contributes to the complications of thoracic radiotherapy. RILI can be divided into radiation pneumonia (RP) and radiation‐induced fibrosis (RILF). Once RILF occurs, patients will eventually develop irreversible respiratory failure; thus, a new treatment strategy prevent is urgently needed. This study explored therapeutic effect pirfenidone (PFD), Food Drug Administration (FDA)‐approved drug for (IPF) treatment, its mechanism in RILF. In...
Abstract The human visual perceptual system is highly sensitive to biological motion (BM) but less its inverted counterpart. This inversion effect may stem from our selective sensitivity gravity-constrained life signals and confer an adaptive advantage creatures living on Earth. However, what extent how such shaped by the Earth’s gravitational field heretofore unexplored. Taking of a spaceflight experiment ground-based analog via 6° head-down tilt bed rest (HDTBR), we show that prolonged...
Significance Impaired visual processing of biological motion (BM) is inextricably linked to compromised social cognitive abilities in autism spectrum disorder (ASD). Using behavioral genetic methodology, we demonstrate that genes contribute interindividual variation BM perception and autistic traits. More importantly, the ability process local rather than global configuration heritable, former negatively correlated with traits, covariance mainly attributable shared factors. These findings...
The effects of heat treatment on the antigenicity and potential allergenicity α-Lactalbumin (α-LA), β-Lactoglobulin (β-LG), α-casein (α-CN), β-casein (β-CN) in milk protein concentrates (MPCs) were investigated at temperatures range 65–100°C for times from 10 to 30 min. α-LA decreased significantly. β-LG was sharply increased throughout treatment, while significantly only 85°C 100°C 25 α-CN β-CN showed fluctuated changes, but all lower than untreated sample. when heated 65°C 70°C Compared...
BACKGROUND Cow's milk allergy has aroused public concern. The aim of this study was to investigate the effects fermentation by Lactobacillus casei 1134 on antigenicity and allergenicity (IgE-binding inhibitions) proteins. pH value four proteins (α-lactalbumin, β-lactoglobulin, α-casein β-casein) were examined indirect competitive enzyme-linked immunosorbent assay. free amino acids which produced in process analysed proteolysis detected. RESULTS Fermentation L. could significantly reduce...
LHEPS-1 exhibited the strongest anti-proliferation effect, prevented G<sub>1</sub> to S transition and increased apoptosis of human colon cancer HT-29 cells.
The poor prognosis of locally advanced and metastatic head neck squamous cell carcinoma (HNSCC) is primarily mediated by the functional properties cancer stem cells (CSCs) resistance to chemoradiotherapy. We investigated whether aldehyde dehydrogenase (ALDH) inhibitor disulfiram (DSF) can enhance sensitivity therapy. Cell viability was assessed 1-(4,5-dimethylthiazol-2-yl)-3,5-diphenylformazan (MTT) apoptosis assays, cycle reactive oxygen species (ROS) levels were evaluated...
In this study, the effects of fermentation by Lactobacillus rhamnosus GG on antigenicity and Immunoglobulin E (IgE)-binding inhibitions α-lactalbumin (LA), β-lactoglobulin (LG), α- caseins (CN) β-CN were investigated, using polyclonal antibodies milk-allergic patient sera in competitive enzyme-linked immunosorbent assay (ELISA). Meanwhile, proteolysis milk proteins was detected trinitrobenzene sulfonic acid (TNBS) sodium dodecyl sulphate polyacrylamide gel electrophoresis (SDS-PAGE). As a...
The prebiotic potential of exopolysaccharide (r-EPS) structures released from Lactobacillus delbrueckii ssp. bulgaricus SRFM-1 was assessed using in vitro fermentations. Fermentations with pure cultures (nine strains) and a Streptococcus strain as well two food-borne pathogenic Escherichia coli were performed. Scanning electron microscopy Congo red testing revealed that the three r-EPS fractions had different individual structures. All found to stimulate growth lactobacilli inhibit E....
Activation of the renin-angiotensin system has been implicated in hypertension. Angiotensin (Ang) II is a potent proinflammatory mediator. The present study investigated role myeloid angiotensin type 1 receptor (AT1R) control macrophage phenotype vitro and vascular injury deoxycorticosterone acetate (DOCA)/salt In human THP-1/macrophages, Ang increased mRNA expressions M1 cytokines decreased M2 cytokine expressions. Overexpression AT1R further II-induced cytokines. Silenced reversed changes...
In order to explore the aromatic differences between Xinjiang cow milk powder and specialty (donkey, camel, horse powder), Gas Chromatography-Ion Mobility Spectrometry (GC-IMS) analysis was employed investigate volatile compounds in these four types of powders. A total 61 substances were detected, with ketones, aldehydes, alcohols being primary flavor components While different powders showed similarities terms types, there significant their concentrations, exhibiting distinct...
To investigate the characteristic aromatic compounds, present in traditional fermented koumiss of Kazakh ethnic group different regions Xinjiang, GC-IMS, and GC-MS were used to analyze volatile compounds from four regions. A total 87 substances detected, esters, acids, alcohols found be main aroma koumiss. While types similar across regions, differences their concentrations significant displayed clear regional characteristics. The fingerprint spectrum combined with PLS-DA analysis, indicates...
Abstract C hinese J unzao jujube in X injiang is a high‐quality brew resource because of its high sugar content. Jujube paste was hydrolyzed by multi‐enzyme and then fermented with D aqu yeast through solid‐state fermentation process. After distilling aging, the final product has typical characteristic brandy. The optimal hydrolysis conditions were mixture pectinase cellulase ratio 1:3, dosage 0.75% (w/w), an enzymolysis pH 3.5–4.0, temperature 50 time 3 h. process as follows: active dry...
The cyclin-dependent protein kinases (CDKs) are protein-serine/threonine with crucial effects on the regulation of cell cycle and transcription. CDKs can be a hallmark cancer since their excessive expression could lead to impaired proliferation. However, selectivity profile most developed CDK inhibitors is not enough, which have hindered therapeutic use inhibitors. In this study, we propose multitask deep learning framework called BiLAT based SMILES representation for prediction inhibitory...
Fast detection of ambient danger is crucial for the survival biological entities. Previous studies have shown that threatening information can bias human visual perception and enhance physiological reactions. It remains to be delineated whether modulation threat on perceptual responses take place below awareness. To probe this issue, we adopted looming stimuli created two levels by varying their motion trajectories observers, such could move in a path either collided with observers' heads or...