Christine D. Esper

ORCID: 0000-0002-1093-6537
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About
Contact & Profiles
Research Areas
  • Neurological disorders and treatments
  • Parkinson's Disease Mechanisms and Treatments
  • Botulinum Toxin and Related Neurological Disorders
  • Balance, Gait, and Falls Prevention
  • Microtubule and mitosis dynamics
  • Transcranial Magnetic Stimulation Studies
  • Genetic Neurodegenerative Diseases
  • Moyamoya disease diagnosis and treatment
  • Neurological Complications and Syndromes
  • Parkinson's Disease and Spinal Disorders
  • Schizophrenia research and treatment
  • Glycogen Storage Diseases and Myoclonus
  • Muscle activation and electromyography studies
  • Neurological diseases and metabolism
  • Telemedicine and Telehealth Implementation
  • Cerebral Palsy and Movement Disorders
  • Gait Recognition and Analysis
  • Pharmacological Effects and Toxicity Studies
  • Voice and Speech Disorders
  • Innovations in Medical Education
  • Assistive Technology in Communication and Mobility
  • COVID-19 and healthcare impacts
  • Oral and gingival health research
  • Dysphagia Assessment and Management
  • Systemic Sclerosis and Related Diseases

Emory University
2007-2025

Neurology, Inc
2022-2025

Emory and Henry College
2024

Brigham and Women's Hospital
2005

Massachusetts General Hospital
2005

Harvard University
2005

Freezing of gait (FOG) is a poorly understood heterogeneous disorder seen in patients with parkinsonism which contributes to significant morbidity and social isolation. FOG currently measured scales that are typically performed by movement disorders specialists (i.e., MDS-UPDRS), or through patient completed questionnaires (N-FOG-Q) both inadequate addressing the nature unsuitable for use clinical trials The purpose this study was devise method measure objectively, hence improving our...

10.3390/s23041766 article EN cc-by Sensors 2023-02-04

Abstract Our objective was to evaluate the ability of neurologists recognize and diagnose drug‐induced Parkinsonism (DIP) in elderly. DIP is a diagnostic challenge because it can be indistinguishable from Parkinson's disease, especially It frequently under‐recognized by psychiatrists primary care physicians. Atypical antipsychotics (AA) are advertised for their low propensity cause DIP. This may add problems with recognition. We performed retrospective record review consecutive new...

10.1002/mds.21854 article EN Movement Disorders 2007-12-07

The authors report a patient with Guillain-Barré syndrome who developed acute hypertension, reversible posterior leukoencephalopathy syndrome, ischemic and hemorrhagic strokes, cerebral arterial vasoconstriction shortly after initiating intravenous immune globulin therapy. Possible interrelationships mechanisms of these complications are discussed.

10.1177/1051228404273820 article EN Journal of Neuroimaging 2005-03-03

Outcomes after deep brain stimulation (DBS) therapy are dependent on good surgical placement in the target nucleus and optimized parameters through multiple programming sessions. This often requires frequent travel to a specialized DBS center, which presents challenge for those with limited access. Recently, FDA approved remote tele-programming solution DBS. To determine if of systems is beneficial useful Parkinson's Disease (PD) patients, Foundation hosted survey collaboration Abbott...

10.1016/j.parkreldis.2022.01.017 article EN cc-by Parkinsonism & Related Disorders 2022-01-24

Freezing of gait (FOG) is a debilitating feature Parkinson's disease (PD), which cause injurious falls among PD patients. Recent advances in wearable-based human activity recognition (HAR) technology have enabled the detection FOG subtypes across benchmark datasets. Since manifestation heterogeneous, developing models that quantify consistently patients with varying demographics, types, and conditions important. Bias fairness remain understudied HAR, research focused mainly on using single...

10.48550/arxiv.2502.09626 preprint EN arXiv (Cornell University) 2025-01-29

Telemedicine has rapidly gained momentum in movement disorder neurology during the coronavirus disease (COVID-19) pandemic to preserve clinical care while mitigating risks of in-person visits. We present data from rapid implementation virtual visits a large, academic, practice COVID-19 pandemic.

10.14802/jmd.20099 article EN cc-by-nc Journal of Movement Disorders 2021-03-17

Virtual care, introduced previously as a replacement for in-person visits, is now being integrated into clinical care delivery models to complement visits. The COVID-19 pandemic sped up this process. rapid uptake of virtual at the start prevented educators from taking deliberate steps design foundational elements related learning environment, including workflow, competencies, and assessment methods. Educators must pursue an informed purposeful approach curriculum implement in environment....

10.1097/acm.0000000000004660 article EN Academic Medicine 2022-03-08

Deep brain stimulation (DBS) for Parkinson's disease (PD) is generally contraindicated in persons with dementia but it frequently performed people mild cognitive impairment or normal cognition, and current clinical guidelines are primarily based on these cohorts.

10.1002/mdc3.13660 article EN Movement Disorders Clinical Practice 2023-01-16

Characterizing motor subtypes of Parkinson's disease (PD) is an important aspect clinical care that useful for prognosis and medical management. Although all PD cases involve the loss dopaminergic neurons in brain, individual may present with different combinations signs, which indicate differences underlying pathology potential response to treatment. However, conventional method distinguishing involves resource-intensive physical examination by a movement disorders specialist. Moreover,...

10.3390/s23198330 article EN cc-by Sensors 2023-10-09

Freezing of gait (FOG) is a poorly understood heterogeneous disorder seen in patients with parkinsonism which contributes to significant morbidity and social isolation. FOG currently measured scales that are typically performed by movement disorders specialists (ie. MDS-UPDRS), or through patient completed questionnaires (N-FOG-Q) both inadequate addressing the nature unsuitable for use clinical trials The purpose this study was devise method measure objectively, hence improving our ability...

10.1101/2023.01.13.23284535 preprint EN cc-by-nc-nd medRxiv (Cold Spring Harbor Laboratory) 2023-01-18

To assess relationship of tremor reduction and volume lesion post Focused Ultrasound (FUS) therapy in Essential Tremor (ET) Parkinson Disease (PD) patients.

10.1212/wnl.0000000000206662 article EN Neurology 2024-04-09

The authors report a patient with Guillain-Barré syndrome who developed acute hypertension, reversible posterior leukoencephalopathy syndrome, ischemic and hemorrhagic strokes, cerebral arterial vasoconstriction shortly after initiating intravenous immune globulin therapy. Possible interrelationships mechanisms of these complications are discussed.

10.1111/j.1552-6569.2005.tb00305.x article EN Journal of Neuroimaging 2005-04-01

<h3>Objective:</h3> The purpose of this study is to use whole-body kinematics data during walking accurately identify motor subtypes Parkinson's disease (PD) and parkinsonism. <h3>Background:</h3> Two major PD have been described, Postural Instability Gait Disorder (PIGD) Tremor Dominant (TD), which differ in the prognosis. Prior studies explored quantifying via gait analysis, lacks for movements that are required when analyzing an entire cycle. In study, we measure while walking, then...

10.1212/wnl.0000000000203887 article EN Neurology 2023-04-25

Abstract Tremor, defined as an “involuntary, rhythmic, oscillatory movement of a body part,” is key feature many neurological conditions, but still clinically assessed by visual observation. Methodologies for objectively quantifying tremor are promising remain non-standardized across centers. Our center performs full-body behavioral testing with 3D motion capture clinical and research purposes patients Parkinson’s disease, essential tremor, other conditions. The objective this study was to...

10.1101/2024.03.13.24304101 preprint EN cc-by medRxiv (Cold Spring Harbor Laboratory) 2024-03-16

To compare gait parameters in a large cohort of Parkinson's Disease (PD) and Essential Tremor (ET) patients using 3D kinematic analysis.

10.1212/wnl.0000000000204945 article EN Neurology 2024-04-09
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