A5072816996- X-ray Diffraction in Crystallography
- Crystallization and Solubility Studies
- Metal complexes synthesis and properties
- Organometallic Compounds Synthesis and Characterization
- Ferrocene Chemistry and Applications
- Chemical Synthesis and Characterization
- Crystal structures of chemical compounds
- Synthesis and Characterization of Heterocyclic Compounds
- Synthesis and biological activity
- Crystallography and molecular interactions
- Free Radicals and Antioxidants
- Polyoxometalates: Synthesis and Applications
- Chemical and Physical Properties in Aqueous Solutions
- Antimicrobial agents and applications
- Porphyrin and Phthalocyanine Chemistry
- Nanocomposite Films for Food Packaging
- Antimicrobial Peptides and Activities
- Antibiotic Resistance in Bacteria
- Protein Interaction Studies and Fluorescence Analysis
- Magnetism in coordination complexes
- Contact Dermatitis and Allergies
- Click Chemistry and Applications
- Metal-Organic Frameworks: Synthesis and Applications
University of Pavol Jozef Šafárik
2016-2024
Technical University of Košice
2019-2020
Novel silver(<sc>i</sc>) aminoacidate complexes {[Ag(HVal)(H<sub>2</sub>O)(NO<sub>3</sub>)]}<sub>n</sub> (AgVal) and {[Ag<sub>3</sub>(HAsp)<sub>2</sub>(NO<sub>3</sub>)]}<italic>n</italic>·<italic>n</italic>H<sub>2</sub>O (AgAsp) were prepared, investigated, fully characterized their antibacterial, anticancer DNA cleavage activities evaluated.
Silver( i ) complexes show antibacterial and cytotoxic activity in ovo experiments predict their safe use for local or intravenous applications. Fluorescence quenching lipophilicity indicate suitable bioavailability.
Three silver(I) dipeptide complexes [Ag(GlyGly)]n(NO3)n (AgGlyGly), [Ag2(GlyAla)(NO3)2]n (AgGlyAla) and [Ag2(HGlyAsp)(NO3)]n (AgGlyAsp) were prepared, investigated characterized by vibrational spectroscopy (mid-IR), elemental thermogravimetric analysis mass spectrometry. For AgGlyGly, X-ray crystallography was also performed. Their stability in biological testing media verified time-dependent NMR measurements. vitro antimicrobial activity evaluated against selected pathogenic microorganisms....
Abstract A series of novel Ga(III)—pyridine carboxylates ([Ga(Pic) 3 ]·H 2 O (GaPic; HPic = picolinic acid), H O[Ga(Dpic) (GaDpic; Dpic dipicolinic [Ga(Chel)(H O)(OH)] ·4H (GaChel; Chel chelidamic acid) and [Ga(Cldpic)(H (GaCldpic; Cldpic 4-chlorodipicolinic acid)) have been synthesized by simple one-step procedure. Vibrational spectroscopy (mid-IR), elemental analysis, thermogravimetric analysis X-ray diffraction confirmed complexes molecular structure, inter intramolecular interactions...
Two silver(i) complexes, {[Ag7(2-pypo)3(NO3)]} n (1) and [Ag(3-pypoH)(3-pypoH2)] (2) (pypoH2 - pyridylphosphonic acid) were prepared characterized by relevant methods in the solid state (elemental, spectral, thermal structural analysis). Typical argentophilic interactions observed complex 1. The synthesized Ag(i) complexes tested toward reduction to silver(0) using short wavelength UV-radiation they revealed remarkable light-insensitivity comparison silver nitrate. SEM experiments performed...
Two silver(I) complexes with biological relevant heterocyclic ligands, pyrrole and furan-2- carboxylic acid, were synthesized their composition confirmed using elemental, spectral, thermal structural analyses. The {[Ag(Py2c)]}n(AgPy2c, Py2c = pyrrole-2-carboxylate) {[Ag(Fu2c)]}n(AgFu2c, Fu2c furan-2-carboxylate) solubility stability in test stock solution by 1H NMR spectroscopy. X-ray analysis has enabled us to determine typical argentophilic interactions bridge carboxylate coordination mode...
Abstract The aim of this study was to evaluate the antibacterial activity, quality and stability creams (at 1 % concentration) prepared with synthesized silver(I) complexes: [Ag(Nam) 2 ]NO 3 ·H O ( AgNam), [Ag (HGly) ] n (NO ) 2n (AgGly) (Nam – nicotin-amide, Gly glycine) sulfadiazine (AgSD), which is commercially available. Antibacterial activity evaluated by agar well diffusion method in vivo case. pure complexes as all three tested loaded AgGly, AgSD AgNam showed potential. Moreover,...