A5063118127- Voice and Speech Disorders
- Dysphagia Assessment and Management
- Tracheal and airway disorders
- Stuttering Research and Treatment
- Botulinum Toxin and Related Neurological Disorders
- Ear Surgery and Otitis Media
- Respiratory and Cough-Related Research
- Airway Management and Intubation Techniques
- Head and Neck Cancer Studies
- Salivary Gland Tumors Diagnosis and Treatment
- Head and Neck Surgical Oncology
- Diversity and Career in Medicine
- Sinusitis and nasal conditions
- Neurological disorders and treatments
- Otolaryngology and Infectious Diseases
- Phonetics and Phonology Research
- Head and Neck Anomalies
- Helicobacter pylori-related gastroenterology studies
- Trauma Management and Diagnosis
- Hearing, Cochlea, Tinnitus, Genetics
- Gender Diversity and Inequality
- Antimicrobial Peptides and Activities
- Streptococcal Infections and Treatments
- Facial Trauma and Fracture Management
- Radiomics and Machine Learning in Medical Imaging
Maimonides Medical Center
2024
University of Washington
2015-2024
Seattle University
2017-2023
University of Washington Medical Center
2016-2019
Mayo Clinic in Arizona
2018
Harborview Medical Center
2011-2012
University of Maryland, Baltimore
2006-2010
Charles Stewart Mott Foundation
2008
University of Wisconsin–Madison
2008
University of Maryland Medical Center
2007
Abstract Objectives/Hypothesis: Cervical necrotizing fasciitis (CNF) is challenging to diagnose and associated with high morbidity mortality. The objective of this study evaluate the utility two laboratory‐based diagnostic tools for distinguishing from non‐necrotizing infection when specifically applied neck infection. Study Design: Retrospective review. Methods: We reviewed 17 consecutive cases CNF 70 (cellulitis, phlegmon, abscess) occurring at our institution over a 10.75‐year period. was...
Objective : Otolaryngic disorders are very common in primary care, comprising 20–50% of presenting complaints to a care provider. There is limited otolaryngology training undergraduate and postgraduate medical education for care.Footnote Continuing may be the next opportunity train our providers (PCPs). The objective this study was assess knowledge group PCPs attending an update course. Methods enrolled course completed web-based anonymous survey on demographics pre-course test. This test...
Objectives/Hypothesis Dysphagia is one of the most significant side effects treatment head and neck cancer. Residue aspiration are two indicators dysphagia, but historically only indicator interest, because it may impact health outcomes. Clinicians have anecdotally used residue as another marker swallowing dysfunction, understudied. This project investigated versus on function quality life (QoL) in these patients. Study Design Observational study. Methods A total 168 cancer survivors with...
Background Described by Schaefer in 1916, frontal cells have been implicated as a cause of recess obstruction. In this cross-sectional study, we determine the prevalence and other anatomic variants examine their relationships. Methods Coronal computed tomography scans sinuses performed from January 2000 to June 2001 were evaluated for cells, variants, sinus disease. Of 1009 evaluated, 768 included data collection. Frontal classified. Results population, 20.4% individuals had (14.9% type I,...
Poor speech intelligibility adversely affects quality of life self-assessment in long term survivors head and neck cancer treatment.Observational case series including both objective clinical testing subjective questionnaire administration.Five-year were recruited to study the association between life. Survivors analyzed as an entire group, also subdivided into laryngectomees non-laryngectomees. Objective included sentence word intelligibility. Subjective questionnaires (UWQOL, FACT,...
This paper uses hedonic analysis to examine the impact of small dam removal on property values in south‐central Wisconsin. Data residential sales were obtained for three categories sites: those where a remains intact, was removed, and river or stream has been free‐flowing at least 20 yr. The primary conclusions that emerge from data are shoreline frontage along impoundments confers no increase value compared streams nonfrontage located vicinity is more valuable than similar impoundment. (...
Abstract Background. Localized amyloidosis of the larynx is a rare entity unclear etiology. Surgical debulking primary treatment modality but often not curative. Methods and Results. A 41‐year‐old woman presenting with increasing hoarseness, dysphagia, dyspnea, weight loss was found to have submucosal mass in left false vocal fold. Biopsy specimen revealed amyloid. After negative work‐up for systemic disease, patient underwent surgical debulking. Specimens population clonal plasma cells...
Objectives/Hypothesis The impact of the disordered voice on standard work productivity measures and employment trends is difficult to quantify; this in large part due heterogeneity disease processes. Spasmodic dysphonia (SD), a chronic disorder, may be useful model study impact. Self‐reported (worked missed, impairment, overall productivity, activity impairment) were studied among patients receiving botulinum toxin (BTX) treatments for SD. It was hypothesized that there would substantial...
The Type I Posterior Glottic Stenosis (PGS-I) is a well-described but uncommon clinical entity. Despite this, there little known about the outcome of surgical treatment.Retrospective case series.Thirteen cases met inclusion criteria. All one patient had tracheostomy at time initial evaluation. At postoperative visit, seven patients (54%) completely normal vocal fold motion. Of verbal patients, 6 (50%) function as reported by both patient/caregiver and physician, 10 (83%) were successfully...
Close to 3% of all intubation attempts are considered difficult airways, for which a plan surgical airway should be considered. Our article provides an overview the different types airways. This comprehensive review main relevant anatomy, necessary equipment, indications and contraindications, preparation positioning, technique, complications, tips management. It is important remember that placement lifesaving procedure in any setting when one "cannot intubate, cannot ventilate".
Objective Although the literature adequately identifies current gender inequality that exists in academic otolaryngology and describes barriers to advancement of women medicine, there is little information regarding daily details how successful achieve work‐life balance. This study was designed better understand balance while negotiating family childrearing commitments, clinical workload, scholarly activity, as well highlight coping strategies behaviors have used these successes. Study...
The repair of large tracheal segmental defects remains an unsolved problem. goal this study is to apply tissue engineering principles for the fabrication trachea replacements. Engineered replacements composed autologous cells (neotracheas) were tested in a New Zealand White rabbit model. Neotracheas formed neck by wrapping silicone tube with consecutive layers skin epithelium, platysma muscle, and engineered cartilage sheet allowing construct mature 8–12 weeks. In total, 28 rabbits implanted...
Immune checkpoint blockade can provide clinical benefit for patients with advanced cancer. Here, we report durable disease control over many years following PD-L1 through induction of a viral antigen-specific T cell response in an adult patient recurrent respiratory papillomatosis.Antigen-specific assays, single RNA-sequencing, and RNA-scope was used to study tissues.An HPV6 E2-specific clone restricted HLA-B*55, present at low frequency the pre-treatment papilloma, significantly expanded...
Abstract Rak is a 54 kDa protein tyrosine kinase originally isolated from breast cancer cells and expressed in epithelial cells. It resembles the protooncogene Src structurally but lacks an amino‐terminal myristylation site localizes to nuclear perinuclear regions of cell. We report here that expression 2 different cell lines inhibits growth causes G 1 arrest cycle. This inhibition kinase‐dependent does not require SH2 or SH3 domain. also binds pRb tumor‐suppressor even lack pRb. These...
Objectives: To review the importance of mucin on a molecular level in understanding pathophysiology otitis media and to present new data demonstrating differential up-regulation specific genes during inflammation middle ear epithelium.Design: Primary chinchilla epithelial cultures (CMEECs) were established exposed tumor necrosis factor ␣ interleukin 1.Expression chincilla 1, 2, 4, 5AC was analyzed by means reverse transcriptase-polymerase chain reaction after this exposure compared with...