Daniela Silva Gonçalves

ORCID: 0000-0002-1120-0644
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About
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Research Areas
  • Natural Antidiabetic Agents Studies
  • Essential Oils and Antimicrobial Activity
  • Phytochemistry Medicinal Plant Applications
  • Antifungal resistance and susceptibility
  • Bioactive Compounds and Antitumor Agents
  • Child Therapy and Development
  • Palliative and Oncologic Care
  • Antimicrobial Peptides and Activities
  • Natural product bioactivities and synthesis
  • Cholinesterase and Neurodegenerative Diseases
  • Psychology and Mental Health
  • Psidium guajava Extracts and Applications
  • Phytochemistry and biological activity of medicinal plants
  • Phytochemicals and Antioxidant Activities
  • Bacterial biofilms and quorum sensing
  • Bee Products Chemical Analysis
  • Medicinal Plants and Neuroprotection
  • Natural Compounds in Disease Treatment
  • Pharmacological Effects of Natural Compounds

Universidade Federal de Uberlândia
2023-2025

Abstract Candida species have been responsible for a high number of invasive infections worldwide. In this sense, Rottlerin has demonstrated wide range pharmacological activities. Therefore, study aimed to evaluate the antifungal, antibiofilm and antivirulence activity in vitro against spp. its toxicity antifungal vivo. showed all yeasts evaluated, presenting Minimum Inhibitory Fungicidal Concentration (MIC MFC) values 7.81 > 1000 µg/mL. Futhermore, it was able significantly inhibit...

10.1038/s41598-024-61179-z article EN cc-by Scientific Reports 2024-05-15

Abstract Aims Evaluate the in vitro and vivo effects of catecholic chalcones their derivatives against phytopathogenic bacteria toxicity. Methods Results Antibacterial testing was conducted using Minimum Inhibitory Bactericidal Concentrations (MIC/MBC) assays. The Fractional Concentration Index calculated. Inhibition enzymatic activity indicated by halos measurement. Toxicity study used Caenorhabditis elegans model bacterial leaf spot control tomato evaluated vivo. Catecholic 1 (3-Br), 2...

10.1093/jambio/lxaf094 article EN Journal of Applied Microbiology 2025-04-17

Drug-resistant bacteria constitute a big barrier against current pharmacotherapy. Efforts are urgent to discover antibacterial drugs with novel chemical and biological features. Our work aimed at the synthesis, evaluation of effects, toxicity licochalcone C (LCC), naturally occurring chalcone. The synthetic route included six steps, affording 10% overall yield. LCC showed effects Gram-positive (MIC = 6.2–50.0 µg/mL), Mycobacterium species 36.2–125 Helicobacter pylori 25 µg/mL). inhibited...

10.3390/ph17050634 article EN cc-by Pharmaceuticals 2024-05-14

Even though Brazil has a large biodiversity of medicinal plants, many them have not had their chemical and biological potential acknowledged. Several plants are rich in secondary metabolites with broad antibacterial activity, relevant fact since pathogenic bacteria resistant to conventional antibiotics. Psidium myrtoides, species plant the Myrtaceae family that is known for its sweet purple fruit, should be highlighted this field. It strong antibacterial, antifungal, anti-inflammatory,...

10.5902/2179460x84178 article EN Ciência e Natura 2024-11-22

ABSTRACTObjective: to describe the nursing students’ experience for using therapeutic play (BT) at practical pediatric nursing. Method: this is about a descriptive study from qualitative approach, with data collected through structured questionnaire open questions, applied group of 16 students in private university São Paulo (SP) July September 2009 . The research project was approved by Ethics Research Universidade Paulista UNIP-SP (Protocol 374/09). Results: were analyzed and interpreted...

10.5205/reuol.1262-12560-1-le.0507201132 article PT cc-by Revista de Enfermagem UFPE on line 2011-08-20
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