A5015036883- Essential Oils and Antimicrobial Activity
- Natural product bioactivities and synthesis
- Phytochemistry Medicinal Plant Applications
- Phytochemistry and Biological Activities
- Sesquiterpenes and Asteraceae Studies
- Crystallization and Solubility Studies
- Oral microbiology and periodontitis research
- X-ray Diffraction in Crystallography
- Bee Products Chemical Analysis
- Plant Toxicity and Pharmacological Properties
- Traditional and Medicinal Uses of Annonaceae
- Psidium guajava Extracts and Applications
- Antifungal resistance and susceptibility
- Phytochemistry and Bioactivity Studies
- Bacterial biofilms and quorum sensing
- Synthesis and biological activity
- Bioactive Natural Diterpenoids Research
- Ethnobotanical and Medicinal Plants Studies
- Endodontics and Root Canal Treatments
- Metal complexes synthesis and properties
- Plant chemical constituents analysis
- Dental materials and restorations
- Insect Pest Control Strategies
- Phytochemical compounds biological activities
- Toxoplasma gondii Research Studies
Universidade Federal de Uberlândia
2011-2025
Institute of Biomedical Science
2025
Universidade Federal do Amapá
2024
Universidade de São Paulo
2002-2023
Universidade de Rio Verde
2023
Instituto Federal de Educação, Ciência e Tecnologia do Triângulo Mineiro
2023
Universidade de Ribeirão Preto
2002-2023
Universidade de Franca
2013-2022
GTx (United States)
2018-2020
Universidade Federal de Santa Catarina
2018
Abstract The in vitro inhibitory activity of crude EtOH/H 2 O extracts from the leaves and stems Rosmarinus officinalis L. was evaluated against following microorganisms responsible for initiating dental caries: Streptococcus mutans, S. salivarius, sobrinus, mitis, sanguinis , Enterococcus faecalis. Minimum concentrations ( MIC ) were determined with broth microdilution method. bioassay‐guided fractionation leaf extract, which displayed higher antibacterial than stem led to identification...
The purpose of this in vitro study was to evaluate the antimicrobial activity acrylic resins containing different percentages silver and zinc zeolite, assess whether addition zeolite alters flexural impact strength resins.The characteristics support microorganism development that can threaten health dentures user.A microwave-polymerised (Onda-Cryl) two heat-polymerised (QC20 Lucitone 550) were used. materials handled according manufacturers' instructions. Fifty rectangular-shaped specimens...
In this work, we used the Minimum Inhibitory Concentration (MIC) technique to evaluate antibacterial potential of apitoxin produced by Apis mellifera bees against causative agents tooth decay. Apitoxin was assayed in natura and commercially available form. The actions main components apitoxin, phospholipase A2, melittin were also assessed, alone combination. following bacteria tested: Streptococcus salivarius, S. sobrinus, mutans, mitis, sanguinis, Lactobacillus casei, Enterococcus faecalis....
Tooth decay is a major public health problem which affects large number of people in several countries. Even though more than 700 bacterial species have been detected the oral cavity, Streptococcus and Lactobacillus stand out as genera that cause tooth other periodontal diseases. In this study, essential oils from Citrus aurantifolia leaves (CL-EO) fruit peel (CP-EO) were obtained by hydrodistillation Clevenger-type apparatus whereas their chemical composition was analyzed gas...
The antimicrobial activity of four labdane-type diterpenes isolated from the oleoresin Copaifera langsdorffii as well two commercially available (sclareol and manool) was investigated against a representative panel microorganisms responsible for periodontitis. Among all evaluated compounds, (−)-copalic acid (CA) most active, displaying very promising MIC value (3.1 µg mL−1; 10.2 µM) key pathogen (Porphyromonas gingivalis) involved in this infectious disease. Moreover, CA did not exhibit...
Abstract In the present work, anticariogenic activities of nine labdane type‐diterpenes and four sesquiterpenes were investigated. Among these metabolites, (‐)‐copalic acid (CA) was most active compound displaying MIC values very promising (ranging from 2.0 to 6.0 µg/mL) against main microorganisms responsible for dental caries: Streptococcus salivarius, S. sobrinus, mutans, mitis, sanguinis Lactobacillus casei . Time kill assays performed with CA primary causative agent ( mutans ) revealed...
The antimicrobial activity of Syzygium cumini leaves extract, known as "jambolão", was evaluated. crude hydroalcoholic extract active against Candida krusei (inhibition zone 14.7 ± 0.3 mm and MIC = 70 µg/mL), multi-resistant strains Pseudomonas aeruginosa, Klebsiella pneumoniae Staphylococcus aureus.
Seven pimarane type-diterpenes re-isolated from Viguiera arenaria Baker and two semi-synthetic derivatives were evaluated in vitro against the following main microorganisms responsible for dental caries: Streptococcus salivarius, S. sobrinus, mutans, mitis, sanguinis Lactobacillus casei. The compounds ent-pimara-8(14),15-dien-19-oic acid (PA); ent-8(14),15-pimaradien-3beta-ol; ent-15-pimarene-8beta,19-diol; ent-8(14),15-pimaradien-3beta-acetoxy sodium salt derivative of PA most active...
This study evaluated the antibacterial and antiproliferative activities of essential oil Psidium guajava leaves (PG-EO), traditionally used in folk medicine. The was obtained from fresh by hydrodistillation, using a modified Clevenger apparatus. major PG-EO chemical constituents were identified GC-MS GC-FID as being β-caryophyllene (16.1%), α-humulene (11.9%), aromadendrene oxide (14.7%), δ-selinene (13.6%), selin-11-en-4α-ol (12.5%). activity P. determined terms its minimum inhibitory...
Triterpene acids (ursolic, oleanoic, gypsogenic, and sumaresinolic acids) isolated from Miconia species, along with a mixture of ursolic oleanolic maslinic 2-a-hydroxyursolic acids, as well acid derivatives were evaluated against the following microorganisms: Streptococcus mutans, mitis, sanguinis, salivarius, sobrinus, Enterococcus faecalis, which are potentially responsible for formation dental caries in humans. The microdilution method was used determination minimum inhibitory...
EXTRACTS AND PURE COMPOUNDS.In this work, the effectiveness of four screening techniques (three diffusion method and one microdilution broth method) were compared.Evaluated ethanolic dichloromethanic extracts Miconia rubiginosa (Melastomataceae) against six standard bacteria (ATCC).The results showed statistical disagreement among three techniques.Among techniques, well technique displayed best result.However demonstrated to be most adequate evaluate antibacterial activity plant crude pure...
Abstract The activities of the crude ethanol extract from Piper cubeba seeds, (‐)‐cubebin and its semi‐synthetic derivatives were evaluated against oral pathogens. was more active Streptococcus salivarius (MIC value 80 µg/mL). (‐)‐Cubebin displayed MIC values ranging 0.20 m for mitis to 0.35 Enterococcus faecalis . natural product derivative (‐)‐hinokinin bacteriostatic activity at all concentrations, as well fungicidal Candida albicans 0.28 O‐benzyl cubebin showed fungistatic effects C. ,...
The present article describes an l-amino acid oxidase from Bothrops atrox snake venom as with antiprotozoal activities in Trypanosoma cruzi and different species of Leishmania (Leishmania braziliensis, donovani major). Leishmanicidal effects were inhibited by catalase, suggesting that they are mediated H(2)O(2) production. spp. cause a spectrum diseases, ranging self-healing ulcers to disseminated often fatal infections, depending on the involved host's immune response. BatroxLAAO also...
The essential oil of Rosmarinus officinalis L. (rosemary) was obtained by hydro-distillation and analysed gas chromatography-mass spectrometry. Sixty-two constituents were identified, representing 98.06% the total content. Oxygenated monoterpenes predominant components. rosemary characterized as having prominent (> 5%) contents camphor (18.9%), verbenone (11.3%), α-pinene (9.6%), β-myrcene (8.6%), 1,8-cineole (8.0%), β-caryophyllene (5.1%). antimicrobial activity well its major tested...
In Brazilian folk medicine, Tetradenia riparia (Hochst.) Codd. (Lamiaceae) is used to treat toothaches and dental abscesses diseases induced by worms, bacteria, or fungi. This paper aims investigate the chemical composition antibacterial effects of essential oil obtained from leaves (TR-EO) grown in Southeastern Brazil against a representative panel oral pathogens. We evaluated activity TR-EO terms minimal inhibitory concentration (MIC). identified aromadendrene oxide (14.0%), (E,E)-farnesol...
Dental prosthesis supports Candida species growth and may predispose the oral cavity to lesions. C. tropicalis has emerged as a colonizer of shown resistance clinically used antifungal agents, which increased search for new antifungals. This work describes effectiveness fifteen essential oils (EOs) against The EOs were obtained by hydrodistillation chemically characterized gas chromatography-mass spectrometry. activities evaluated microdilution method showed that Pelargonium graveolens...
This work investigated the antibacterial activity of 15 commercially available plant-derived essential oils (EOs) against a panel oral pathogens. The broth microdilution method afforded minimum inhibitory concentrations (MICs) and bactericidal (MBCs) assayed EOs. EO obtained from Cinnamomum zeylanicum (Lauraceae) (CZ-EO) displayed moderate Fusobacterium nucleatum (MIC MBC = 125 μg/mL), Actinomyces naeslundii Prevotella nigrescens μg/mL) Streptococcus mutans 200 μg/mL; 400 μg/mL)....
Many studies have reported that medicinal plant extracts can inhibit oral pathogen growth or adhesion to surfaces and therefore reduce dental caries formation. The addition of these products like mouthwashes dentifrices is considered an important strategy in control. In this sense, we developed a Mikania glomerata extract with high ent-kaurenoic acid content (KAMg). So, work describes the preparation such development validated HPLC-DAD method determine its (KA) content. Herein it also...
Many essential oils (EOs) of different plant species possess interesting antimicrobial effects on buccal bacteria and antioxidant properties. Eugenia klotzschiana Berg (pêra-do-cerrado, in Portuguese) is a Myrtaceae with restricted distribution the Cerrado. The were extracted through hydrodistillation technique using modified Clevenger apparatus (2 hours) chemically characterized by GC-MS. major compounds α-copaene (10.6 %) found oil from leaves natura, β-bisabolene (17.4 dry...