A5008084562- Plant-derived Lignans Synthesis and Bioactivity
- Traditional and Medicinal Uses of Annonaceae
- Receptor Mechanisms and Signaling
- Trypanosoma species research and implications
- Research on Leishmaniasis Studies
- Education Pedagogy and Practices
- Synthetic Organic Chemistry Methods
- Parasites and Host Interactions
- Insect Pest Control Strategies
- Alkaloids: synthesis and pharmacology
- Evasion and Academic Success Factors
- Bioactive Compounds and Antitumor Agents
- Synthesis and biological activity
- Cholinesterase and Neurodegenerative Diseases
- Arts and Performance Studies
- History, Culture, and Society
- Science and Education Research
- Hormonal Regulation and Hypertension
- Cardiac electrophysiology and arrhythmias
- Piperaceae Chemical and Biological Studies
- Urban and sociocultural dynamics
- Nuclear Receptors and Signaling
- Cell Adhesion Molecules Research
- Nitric Oxide and Endothelin Effects
- Renin-Angiotensin System Studies
Universidade Municipal de São Caetano do Sul
2024
Universidade de São Paulo
2003-2021
Universidade de Franca
2007-2011
Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo
1998-2004
Universidade de Ribeirão Preto
2003
Abstract The activities of the crude ethanol extract from Piper cubeba seeds, (‐)‐cubebin and its semi‐synthetic derivatives were evaluated against oral pathogens. was more active Streptococcus salivarius (MIC value 80 µg/mL). (‐)‐Cubebin displayed MIC values ranging 0.20 m for mitis to 0.35 Enterococcus faecalis . natural product derivative (‐)‐hinokinin bacteriostatic activity at all concentrations, as well fungicidal Candida albicans 0.28 O‐benzyl cubebin showed fungistatic effects C. ,...
cAREL is a cAMP-responsive endothelial cell line carrying luciferase reporter gene introduced by stable transfection of enhancer trap into rabbit aortic cells. Luciferase expression in was stimulated 233-fold 8-BrcAMP. Treatment with the beta-adrenoceptor agonist isoproterenol induced 7.0-fold increase expression, which partially blocked either beta1- or beta2-adrenoceptor antagonists and totally propranolol combination plus antagonists. Receptor stimulation mimicked cholera toxin,...
This work reports the results of in vitro assay against extracellular forms Leishmania (viannia) braziliensis eleven dibenzylbutyrolactone derivatives, either isolated from plants or obtained by synthesis. From these, only two showed relative biological activity parasite, raceme mixtures methylpluviatolide: IC50 = 496 mM and (-)-6,6'- dinitrocubebin: 510,4 μM. Thus, it can be suggested that metabolic pathway responsible for these compounds this parasite genera differs one related to...
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O presente artigo tem como objetivo compreender gestores de escolas localizadas em regiões alta vulnerabilidade social conciliam os imperativos do gerencialismo às demandas necessárias à justiça social; além disso, contextualiza a aplicação desses princípios nos processos educacionais. Por meio uma pesquisa natureza exploratória e analítico-descritiva, apresenta análise proveniente respostas públicas estaduais da região metropolitana Grande ABC Paulista. Os resultados estudo apontaram...
O presente estudo tem como objetivo analisar os professores do componente curricular Projeto de Vida, no contexto Novo Ensino Médio, estruturam e conduzem suas atividades avaliativas. A investigação busca compreender a existência critérios claros nesses processos, verificando incorporação desses tanto material didático quanto na prática docente. Para isso, adota-se uma abordagem metodológica qualitativa, que recorre à pesquisa bibliográfica para conceituar o obrigatório avaliação da...
We characterized the role of potential cAMP-responsive elements (CRE) in basal and induced angiotensin converting enzyme (ACE) gene promoter activity order to shed light on regulation somatic ACE expression. identified stimulators repressors expression between 122 288 bp 415 1303 upstream from transcription start site, respectively, using a rabbit endothelial cell (REC) line. These regions also contained associated with response 8BrcAMP. When screening for CRE motifs we found pCRE, proximal...
Abstract For see ChemInform in Full Text.