A5037890097- Essential Oils and Antimicrobial Activity
- Antifungal resistance and susceptibility
- Bee Products Chemical Analysis
- Antibiotic Use and Resistance
- Healthcare Regulation
- Synthesis and biological activity
- Phytochemistry Medicinal Plant Applications
- Bacterial Identification and Susceptibility Testing
- Bacterial biofilms and quorum sensing
- Natural product bioactivities and synthesis
- Toxoplasma gondii Research Studies
- Biosensors and Analytical Detection
- Antimicrobial Resistance in Staphylococcus
- Plant Toxicity and Pharmacological Properties
- Infection Control in Healthcare
- Synthesis and Characterization of Heterocyclic Compounds
- Public Health in Brazil
- Maternal and Neonatal Healthcare
- Oral microbiology and periodontitis research
- Natural Antidiabetic Agents Studies
- Advancements in Transdermal Drug Delivery
- Crystallization and Solubility Studies
- Enterobacteriaceae and Cronobacter Research
- Male Reproductive Health Studies
- Antibiotic Resistance in Bacteria
Universidade Federal de Uberlândia
2019-2024
Universidade de Ribeirão Preto
2024
Universidade de São Paulo
2024
Abstract Candida species have been responsible for a high number of invasive infections worldwide. In this sense, Rottlerin has demonstrated wide range pharmacological activities. Therefore, study aimed to evaluate the antifungal, antibiofilm and antivirulence activity in vitro against spp. its toxicity antifungal vivo. showed all yeasts evaluated, presenting Minimum Inhibitory Fungicidal Concentration (MIC MFC) values 7.81 > 1000 µg/mL. Futhermore, it was able significantly inhibit...
This study aimed at evaluating the potential of Copaifera lucens, specifically its oleoresin (CLO), extract (CECL), and compound ent-polyalthic acid (PA), in combating caries toxoplasmosis, while also assessing toxicity. The involved multiple assessments, including determining minimum inhibitory concentration (MIC) bactericidal (MBC) against cariogenic bacteria. CLO PA exhibited MIC MBC values ranging from 25 to 50 μg/mL, whereas CECL showed equal or exceeding 400 μg/mL. displayed...
We have synthesized twenty-three 1,4-dihydropyridine derivatives (1,4-DHPs) by using a microwave-assisted one-pot multicomponent Hantzsch reaction and evaluated their antibacterial activity against representative panel of cariogenic bacteria in vitro antileishmanial Leishmania (L.) amazonensis promastigotes. Thirteen compounds were moderately active Streptococcus sanguinis, mitis, Lactobacillus paracasei. Compound 22 (diethyl...
Abstract Bacterial and viral infections are serious public health issue. Therefore, this study aimed to evaluate the antibacterial, antibiofilm antiviral potential of Brazilian Red Propolis (BRP) crude hydroalcoholic extract, fractions, isolated compounds, as well their in vivo toxicity. The antibacterial activity was evaluated by determining Minimum Inhibitory Concentration Biofilm (MICB 50 ). viable bacteria count (Log 10 UFC/mL) also obtained. assays were performed infecting BHK-21 cells...
The aim of this study was to evaluate the formation biofilm by Candida spp. isolated from bloodstream, using traditional spectrophotometric methodologies. In addition, goal compare results with those obtained through MALDI-TOF/MS, as well verify its use a potential tool for detection biofilm-forming strains.Hundred and thirteen isolates were studied: 41 albicans, 27 C. tropicalis, 18 glabrata, 17 parapsilosis 10 krusei. Metabolic activity determined tetrazolium salt (XTT) reduction assay...
Fungal infections by Candida spp. are opportunistic and most often occur in individuals with some predisposing factor. Essential oils (EO) have anti-Candida potential, being a therapeutic alternative to be explored, especially for superficial mucosal candidiasis. The objective was analyze the synergistic potential between EO of Citrus limon, Cupressus sempervirens, Litsea cubeba Melaleuca alternifolia, each them clotrimazole, inhibit vitro formation eradication biofilms. Added this, survival...
Background and objectives: Healthcare-Associated Infections are a problem reported by hospitals worldwide, increasing patient morbidity mortality, prolonging hospitalization, health care costs. The hands of professionals still the main source infections, making hand hygiene extremely important for spreading infection control. objective this study was to analyze presence bacteria on after with alcohol gel in Neonatal Unit describe resistance microorganisms antimicrobials. Methods: Hand...
Contamination of the hospital environment with multi-resistant (MDR) Staphylococcus increases risk infection. The aim this study is to identify MDR species on inanimate surfaces, in air, and clinical samples, analyze factors that correlate occurrence infections a Neonatal Intensive Care Unit.Samples surfaces air were taken using premoistened swab (0.9% sodium chloride) spontaneous sedimentation, respectively. isolates recovered from infected neonates. (environmental clinical) identified by...
Bacterial resistance and systemic risks associated with periodontitis underscore the need for novel antimicrobial agents. Cannabis sativa is a promising source of molecules, cannabidiol (CBD) attracts significant interest. This study evaluated antibacterial antibiofilm activity CBD against periodontopathogens, assessed its toxicity in vivo model.
Callistemon viminalis has been widely known due to its therapeutic properties. Tuberculosis is a deadly infectious disease caused predominantly by Mycobacterium tuberculosis. Other respiratory diseases may also be nontuberculous mycobacteria. Malassezia furfur causes dermal inflammation and tissue damage. This study aimed evaluate in vitro inhibitory effects of essential oils (EOs) from C. leaves (EO-CL) flowers (EO-CF) against M. tuberculosis, kansasii, avium strains. Their cytotoxic...
: We have synthesized twenty‐three 1,4‐dihydropyridine derivatives (1,4‐DHPs) by using a microwave‐assisted one‐pot multicomponent Hantzsch reaction and evaluated their antibacterial activity against representative panel of cariogenic bacteria in vitro antileishmanial Leishmania (L.) amazonensis promastigotes amastigotes. Thirteen compounds were moderately active Streptococcus sanguinis, mitis, Lactobacillus paracasei. Compound 22 (diethyl...
Microorganisms can induce diseases with significant clinical implications for human health. Multidrug‐resistant microorganisms have been on the rise worldwide over past few decades, and no new antibiotics introduced to market in a considerable amount of time. Such situation highlights urgency discovering antimicrobial drugs address this pressing issue. Therefore, objective study was identify bioactive compounds against 15 species bacteria 5 fungi relevance through vitro screening 58...
Pterodon pubescens Benth is a Brazilian medicinal plant (sucupira, in Portuguese). This paper aims to determine the volatile composition and antibacterial activities of hexane extract from P. seeds (HE-PP). Antibacterial were screened by microdilution broth method 96-well culture plates MIC values expressed as µg/mL. HE-PP was active against several oral bacteria whose ranged between 12.5 µg/mL 50 three mycobacterial strains (MIC = 125 500 µg/mL). In addition, Xanthomonas citri strain 100...