A5017952023- Bee Products Chemical Analysis
- Essential Oils and Antimicrobial Activity
- Phytochemistry Medicinal Plant Applications
- Insect and Pesticide Research
- Natural product bioactivities and synthesis
- Phytochemistry and Biological Activities
- Healthcare and Venom Research
- Insect Pest Control Strategies
- Plant Toxicity and Pharmacological Properties
- Sesquiterpenes and Asteraceae Studies
- Agricultural and Food Sciences
- Natural Compound Pharmacology Studies
- Medical and Biological Ozone Research
- Ethnobotanical and Medicinal Plants Studies
- Heavy Metals in Plants
- Moringa oleifera research and applications
- Herbal Medicine Research Studies
- Food Science and Nutritional Studies
- Pharmacological Effects of Natural Compounds
- Phytochemicals and Antioxidant Activities
- Salmonella and Campylobacter epidemiology
- Advancements in Transdermal Drug Delivery
- Plant biochemistry and biosynthesis
- Antimicrobial agents and applications
- Yersinia bacterium, plague, ectoparasites research
University of Mississippi
2024-2025
Universidade de São Paulo
2016-2024
Universidade de Ribeirão Preto
2018-2024
Pontificia Universidad Javeriana
2013
The Brazilian red propolis (BRP) constitutes an important commercial asset for northeast beekeepers. role of Dalbergia ecastaphyllum (L.) Taub. (Fabaceae) as the main botanical source this has been previously confirmed. However, in addition to isoflavonoids and other phenolics, which are present resin D. ecastaphyllum, samples BRP reported contain substantial amounts polyprenylated benzophenones, whose was unknown. Therefore, field surveys, phytochemical chromatographic analyses were...
The Brazilian Caatinga green propolis (GP) is known for its significant biological activities; however, incorporation into pharmaceutical formulations hindered by resinous nature and low solubility. This study investigates the analgesic anti-inflammatory effects of both free GP nanoencapsulated (GPN). optimized oil/water nanoformulation maintained stability over a period 28 days, exhibiting minimal alterations in particle size (approximately 200 nm) polydispersity index. GPN demonstrated...
Abstract Brazilian green and red propolis stand out as commercial products for different medical applications. In this article, we report the antimicrobial activities of hydroalcoholic extracts (EGP) (ERP) propolis, well guttiferone E plus xanthochymol (8) oblongifolin B (9) from against multidrug‐resistant bacteria (MDRB). We undertook minimal inhibitory (MIC) bactericidal (MBC) concentrations, inhibition biofilm formation (MICB 50 ), catalase, coagulase, DNase, lipase, hemolysin assays,...
Cancer incidence worldwide is alarming and among the cancers that affect women ovarian cancer most fatal. Many side effects are associated with conventional therapies none of them completely effective, so development new treatments necessary. Brazilian red propolis extract a natural product complex composition great potential for treatment. However, its clinical application harmed due to unfavourable physicochemical characteristics. To enable encapsulation in nanoparticles can be used.The...
Atraphaxis pyrifolia is a native species of Central Asia, known for curing several disorders. The has little knowledges about its chemical composition and any information morphological characteristics despite importance in traditional Asian medicine. This one the first approaches to phytochemical characterization this species. Micro-morphology was performed on stem, leaf parts plant profile morpho-anatomical characters using brightfield, fluorescence, polarized scanning electron microscopy....
Propolis is one of the most widely used products in traditional medicine. One prominent types Brazilian propolis red one, whose primary botanical source Dalbergia ecastaphyllum (L.) Taub. Despite potential for developing new with pharmacological activity, few studies guarantee safety its use. The objective this study was evaluation possible toxic effects and D. ecastaphyllum, as well cytotoxicity assessment main compounds on tumoral cell lines. Hydroalcoholic extracts (BRPE) stems (DSE)...
Seven phenolic compounds (ferulic acid, caffeic 4-methoxycinnamic 3,4-dimethoxycinnamic 3-hydroxy-4-methoxybenzaldehyde, 3-methoxy-4-hydroxypropiophenone and 1-O,2-O-digalloyl-6-O-trans-p-coumaroyl-β-D-glucopyranoside), a flavanonol (7-O-methylaromadendrin), two lignans (pinoresinol matairesinol) six diterpenic acids/alcohol (19-acetoxy-13-hydroxyabda-8(17),14-diene, totarol, 7-oxodehydroabietic dehydroabietic communic acid isopimaric acid) were isolated from the hydroalcoholic extract of...
Skin wound healing is a complex process that requires the mutual work of cellular and molecular agents to promote tissue restoration. In order improve such process, especially in cases impaired (e.g., diabetic ulcer, chronic wounds), there search for substances with properties low toxicity: two features some natural products—such as bee product named propolis—exhibit. Propolis resinous substance obtained from plant resins exudates antioxidant, anti-inflammatory, antitumoral activities, among...
Abstract Introduction Propolis is widely used in folk medicine, and many factors can affect its chemical composition, including abiotic that influence plants bees. Therefore, analytical methods are powerful techniques the quality control of such products. Objective Develop validate an method for quantifying volatile compounds Brazilian brown propolis, evaluate biological activities. Methods A gas chromatography flame ionisation detector (GC‐FID) was validated, attending parameters...
Propolis, produced by honey bees, is used around the world, displaying several corroborated biological activities. Brazil one of leading producers propolis, with a great diversity types, each characteristically chemical fingerprint influenced flora local region. The secondary metabolite's composition propolis strongly impacts its properties, and characterization importance for quality control. Several chromatographic techniques have been applied to characterize highlighting extraction...
Helicobacter pylori is a Gram-negative, microaerophilic, curved-rod, flagellated bacterium commonly found in the stomach mucosa and associated with different gastrointestinal diseases. With high levels of prevalence worldwide, it has developed resistance to antibiotics used its therapy. Brazilian red propolis been studied due biological properties, literature, shown promising antibacterial activities. The aim this study was evaluate anti-H. from crude hydroalcoholic extract (CHEBRP). For...
Abstract Copaifera is a tree that produces an oleoresin has great historical and economic importance. These oleoresins display several pharmacological properties, such as anti‐inflammatory antimicrobial, among others. The commercialization of occurs, in many cases, without any quality control, which facilitates its adulteration. Validated analytical methods can provide safe control. In this work, the 800 Automatic Spinning Band Distillation equipment was used to perform fractionation...
In this study, a comprehensive phytochemical characterization of two morphologically related species from the genus Espeletia Mutis ex Bonpl., namely, grandiflora Humb. & Bonpl. and killipii Cuatrec., Asteraceae, has been performed by gas chromatography coupled to flame ionization detection, mass spectrometry ultra-high performance liquid ultraviolet high-resolution spectrometry. Analysis ethanol extracts (70%, v/v) leaves concomitant compound dereplication allowed identification major...
The antibacterial activity of red propolis extract (RPE) and brown extracts (BPE) the synergistic effect RPE with cefoxitin (CEFO), imipenem (IMI), ertapenem (ERTA) was evaluated in vitro against methicillin-resistant Staphylococcus aureus (MRSA) strains.MRSA ATCC 33591, community-associated (CA-MRSA) USA300, four clinical isolates were used. A broth microdilution assay performed to obtain inhibitory bactericidal concentrations BPE, RPE, CEFO, IMI, ERTA. combination ERTA on formation or...
The Brassicaceae family, commonly referred to as cruciferous plants, is globally cultivated and consumed, with the
Low selectivity and high frequency of side-effects are the major problems currently used chemotherapeutics. Among natural compounds, polyprenylated acylphloroglucinol, guttiferone E, isolated from Brazilian red propolis, has attracted attention due to its marked anticancer properties was evaluated here for role against osimertinib-resistant H1975 cells (with double mutations epidermal growth factor receptor: EGFR L858R/T790M).