A5100758130- Plant Stress Responses and Tolerance
- Ginseng Biological Effects and Applications
- Biological Activity of Diterpenoids and Biflavonoids
- Natural product bioactivities and synthesis
- Photosynthetic Processes and Mechanisms
- Plant Molecular Biology Research
- Cancer-related molecular mechanisms research
- RNA modifications and cancer
- Genomics and Phylogenetic Studies
- MicroRNA in disease regulation
- Circular RNAs in diseases
- Aluminum toxicity and tolerance in plants and animals
- Cancer Cells and Metastasis
- Plant Micronutrient Interactions and Effects
- Geophysical and Geoelectrical Methods
- Plant Gene Expression Analysis
- Mitochondrial Function and Pathology
- Machine Learning in Bioinformatics
- Solidification and crystal growth phenomena
- Bacillus and Francisella bacterial research
- Plant nutrient uptake and metabolism
- Distributed and Parallel Computing Systems
- GABA and Rice Research
- Cruise Tourism Development and Management
- Genetics, Aging, and Longevity in Model Organisms
Tianjin Medical University Cancer Institute and Hospital
2024
Chinese People's Liberation Army
2021-2023
Shandong Academy of Agricultural Sciences
2019-2021
Shandong University
2021
General Hospital of Shenyang Military Region
2019-2021
Institute of Vegetables and Flowers
2019-2020
North China University of Science and Technology
2019
Hunan University
2013-2014
Dalian University of Technology
2014
Shenyang Pharmaceutical University
2010
Circular RNA (circRNA) is a subclass of non-coding RNAs that enables the circular transcripts resistant to exonuclease digestion. Iron homeostasis essential for body maintain normal physiological functions. At present, relationship among circRNA, iron metabolism and heart failure remains largely unknown. This study aimed explore regulatory mechanism circRNA in failure. We obtained miRNA mRNA data from public databases built ceRNA network. The prediction results were verified myocardial...
Multiple sequence alignment (MSA) constitutes an extremely powerful tool for many biological applications including phylogenetic tree estimation, secondary structure prediction, and critical residue identification. However, aligning large sequences with popular tools such as MAFFT requires long runtimes on sequential architectures. Due to the ever increasing sizes of databases, there is demand accelerate this task. In paper, we demonstrate how graphic processing units (GPUs), powered by...
Salt stress is one of the abiotic stresses affecting crop growth and yield. The functional screening mechanism investigation genes in response to salt are essential for development salt-tolerant crops. Here, we found that OXIDATIVE STRESS 2 (OXS2) was a salinity-induced gene, mutant oxs2-1 hypersensitive during seed germination root elongation processes. In absence stress, OXS2 predominantly localized cytoplasm; when plants were treated with salt, entered nuclear. Further RNA-seq analysis...
Background Confident identification of microRNA-target interactions is significant for studying the function microRNA (miRNA). Although some computational miRNA target prediction methods have been proposed plants, results various tend to be inconsistent and usually lead more false positive. To address these issues, we developed an integrated model identifying plant miRNA–target interactions. Results Three online toolkits machine learning algorithms were identify analyze Arabidopsis thaliana...
Abstract Three new dammarane‐type triterpene saponins, 1 – 3 , together with three known compounds, 4 6 were isolated from the aerial parts of Gynostemma pentaphyllum ( Thunb.) Makino . By means chemical and spectroscopic methods, their structures established as (20 S )‐3 β ,20,21‐trihydroxydammara‐23,25‐diene 3‐ O ‐[ α ‐ L ‐rhamnopyranosyl‐(1→2)] [ D ‐xylopyranosyl‐(1→3)]‐ ‐glucopyranosyl‐21‐ ‐glucopyranoside ), R ,23 ,20‐dihydroxy‐19‐oxodammar‐24‐en‐21‐oic acid 21,23‐lactone...
Cytochrome B5 (CB5) family proteins play an important role in various oxidation/reduction reactions cells as the electron donor and are involved a variety of biotic abiotic stress processes. However, function CB5s Brassica rapa is still unclear. In this study, we carried out genome-wide identification, characterization, expression analysis BrCB5s different tissues under adversities stresses. It was identified that fifteen were distributed on chromosomes, which classified into seven groups...
Heavy metal ions which are not essential elements for basic metabolism severely threaten human health through food chain. As the most water-soluble and absorbed heavy ion, Cadmium (Cd) is easily accumulated contaminates plants. Previously, mitochondrial pyruvate carrier 1 (MPC1) was proved to be required Cd tolerance Cd2+ exclusion. In this study, we carried out following mRNA expression profile analysis on Cd-treated mpc1-1 wild-type After further selection of differential expressed genes...
Mitochondrial pyruvate carrier (MPC), which transports into mitochondria, is a key regulatory element in the material metabolism and energy metabolism. Since MPC was firstly identified yeast 2012, many groups have investigated function of MPC. As classic transporter, focus previous studies has been placed on its role transport. In this study, we discovered novel Cd resistant gene, stress-seventy subfamily A 4 (SSA4), can recover sensitive phenotype MPC1 mutant strain. It suggested that,...
Molecular dynamics simulation is a powerful tool to simulate and analyze complex physical processes phenomena at atomic characteristic for predicting the natural time-evolution of system atoms. Precise such as liquid metal solidification has strong requirements both in size computing timescale. Therefore, finding available resources crucial accelerate computation simulations. This paper presents new approach calculation based on previous study implemented CPU clusters, where GPU-based MD...
Introduction Primary blast affects the kidneys due to direct shock wave damage and production of proinflammatory cytokines without effective treatment. CD28 has been reported be involved in regulating T cell activation secretion inflammatory cytokines. The aim this study was investigate influence primary on kidney effect mice. Methods A mouse model blast-induced injury established using a custom-made explosive device. severity investigated by H&E staining. ELISA applied serum...
Objective To investigate the expressions,roles,and clinical significance of microRNA-365(miR-365)and E74-like factor 4(ELF4)in cervical cancer. Methods The expressions miR-365 in normal tissues(n=34),cervical intraepithelial neoplasia 1(CIN 1)(n=31),cervical neoplasia2-3(CIN 2-3)(n=37),squamous cell carcinoma cervix(SCC)(n=33),and three cancer lines(C33A cells,Hela cells,and SiHa cells)were detected by real-time quantitative polymerase chain reaction(qPCR).Bioinformatic prediction and...
The mechanism by which primary shock wave causes lung injury is unclear. aim of this study to find the changes protein that can be helpful in understanding blast-induced injury.A quantitative analysis their global proteome was conducted from mice with blast using LC-MS/MS. Protein annotation, unsupervised hierarchical clustering, functional classification, enrichment and cluster, protein-protein interaction analyses were performed. Furthermore, western blotting used validate changed levels.A...
Soil salinization is one of the causes decline available cultivated land. By improving salt tolerance vegetables, abandoned salinized land can be effectively utilized, saving arable for major crops. We investigated hundreds Chinese cabbage cultivars, by which two most tolerant and sensitive cultivars were selected studied metabolome transcriptome analyses. The results showed that, under stress, metabolites’ response was not closely correlated with gene expressions in tested cabbages....
The system designed in this paper includes map navigation module, information query statistics and analysis update module. module can realize display, scenic spot positioning, detailed display route planning. four modules: business recommendation, public service, popular travel notes, vehicle information. collects the basic entered by tourists when they register, of tourists' operation behaviors, location status, equipment click on page or guide spots. In satisfaction survey intelligent...