Ana Paula de Jesus Santos

ORCID: 0000-0002-1137-5508
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About
Contact & Profiles
Research Areas
  • Advanced biosensing and bioanalysis techniques
  • RNA Interference and Gene Delivery
  • Adenosine and Purinergic Signaling
  • MicroRNA in disease regulation
  • Electromagnetic Fields and Biological Effects
  • Neurological disorders and treatments
  • Planarian Biology and Electrostimulation
  • Pluripotent Stem Cells Research
  • Biosensors and Analytical Detection
  • DNA and Nucleic Acid Chemistry
  • Neuroscience and Neuropharmacology Research
  • Restless Legs Syndrome Research
  • Genetic Neurodegenerative Diseases
  • SARS-CoV-2 detection and testing
  • Bacteriophages and microbial interactions

Universidade de São Paulo
2018-2022

Parkinson's disease (PD) is a neurodegenerative disorder characterized by decreased dopamine bioavailability in the substantia nigra and striatum. Taking into account that adenosine-5'-triphosphate (ATP) its metabolites are intensely released 6-hydroxydopamine (6-OHDA) animal model of PD, screening purinergic receptor gene expression was performed. Effects pharmacological P2Y6 or P2X7 antagonism were studied preventing reversing hemiparkinsonian behavior dopaminergic deficits this model....

10.3389/fncel.2019.00476 article EN cc-by Frontiers in Cellular Neuroscience 2019-11-07
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