A5029124846- Long-Term Effects of COVID-19
- COVID-19 Clinical Research Studies
- Acute Ischemic Stroke Management
- Retinal and Optic Conditions
- Epilepsy research and treatment
- Coenzyme Q10 studies and effects
- Multiple Sclerosis Research Studies
- Migraine and Headache Studies
- Advanced battery technologies research
- Biochemical Acid Research Studies
- COVID-19 and Mental Health
- Trigeminal Neuralgia and Treatments
- Intracerebral and Subarachnoid Hemorrhage Research
- Poisoning and overdose treatments
- Peripheral Neuropathies and Disorders
- Stroke Rehabilitation and Recovery
- Parkinson's Disease Mechanisms and Treatments
- Psychosomatic Disorders and Their Treatments
- EEG and Brain-Computer Interfaces
- Botulinum Toxin and Related Neurological Disorders
- Sarcoidosis and Beryllium Toxicity Research
- Fibromyalgia and Chronic Fatigue Syndrome Research
- Toxoplasma gondii Research Studies
- Alcoholism and Thiamine Deficiency
- Transcranial Magnetic Stimulation Studies
Shahid Beheshti University of Medical Sciences
2015-2024
Shariati Hospital
2023-2024
Tehran University of Medical Sciences
2023-2024
Shahid Beheshti University
2015
Studies have found increased rates of dysosmia in patients with Novel Coronavirus disease 2019 (COVID-19). However, the mechanism that causes olfactory loss is unknown. The primary objective this study was to explore local proinflammatory cytokine levels epithelium COVID-19. Biopsies were taken from confirmed COVID-19 as well uninfected controls. Levels tumor necrosis factor α (TNF-α) and interleukin-1-beta (IL-1β) assessed using ELISA compared between groups. Average TNF-α significantly...
After the novel coronavirus disease outbreak first began in Wuhan, China, December 2019, viral epidemic has quickly spread across world, and it is now a major public health concern. Here we present 21-year-old male with encephalomyelitis following intermittent vomiting malaise for 4 days. He reported upper respiratory signs symptoms 2 weeks before this presentation. Two cerebrospinal fluid (CSF) analyses were notable mononuclear pleocytosis, elevated protein (more than 100 mg/dl),...
The reports of neurological symptoms are increasing in cases with coronavirus disease 2019 (COVID-19). This multi-center prospective study was conducted to determine the incidence manifestations hospitalized COVID-19 and assess these as predictors severity death.Hospitalized males females who aged over 18 years were included study. They examined by two neurologists at time admission. All survived followed for 8 weeks after discharge 16 if their had no improvements.We 873 participants. Of...
The outbreak due to Coronavirus Disease 2019 (COVID-19) is n global public health emergency and challenges psychological resilience. central nervous system, endocrine immune system are complex interacting systems. Cortisol has been implicated as the cause of a wide range mental physical disorders; however, impact cortisol on outcomes in patients with COVID-19 not clear.
Background and Purpose: Stroke is reported as a consequence of severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) infection in several reports. However, data are sparse regarding the details these patients multinational large scale. Methods: We conducted observational study on features consecutive ischemic stroke, intracranial hemorrhage, cerebral venous or sinus thrombosis among SARS-CoV-2–infected patients. further investigated risk vessel occlusion, stroke severity measured by...
Amyotrophic lateral sclerosis (ALS) causes motor neuron loss and progressive paralysis. While traditionally viewed as disease (MND), ALS also affects non-motor regions, such the hypothalamus. This study aimed to quantify hypothalamic subregion volumes in patients with versus healthy controls (HCs) examine their associations demographic clinical features.
Background: Substance abuse leads to blood-brain barrier dysfunction and activation of neuro-inflammatory pathways. However, the contribution serum levels Toll-like receptor 2 (TLR-2) S100 calcium-binding protein B (S100B) neuropsychological outcomes has not been clearly established. This study aims explore relationship between TLR-2 S100B concentrations in individuals with substance their potential influence on results, specifically regarding functioning frontal lobe.Methods: involved 28...
Backgrounds and aims: Clinical studies demonstrated that the efficacy of Coenzyme Q10 (CoQ10) as an adjuvant therapeutic agent in several neurological diseases such Parkinson disease (PD), Huntington (HD), migraine. The purpose this study is to investigate oxidative stress effects, antioxidant enzymes activity, neuroinflammatory markers levels, outcome acute ischemic stroke (AIS) patients following administration CoQ10 (300 mg/day).Methods: Patients with AIS (n = 60) were randomly assigned a...
Objective: The present study aimed to assess the effectiveness of oral citalopram, compared with fluoxetine and a placebo, in patients post-stroke motor disabilities. Design: A randomized double-blind placebo-controlled clinical trial was conducted between January 2015 2016. Setting: neurology department university-affiliated urban hospital Tehran, Iran. Subjects: Ninety adult acute ischemic stroke, hemiplegia, or hemiparesis Fugl-Meyer Motor Scale score below 55 were included....
Abstract Background Congenital myasthenic syndrome (CMS) is a group of neuromuscular disorders caused by abnormal signal transmission at the motor endplate. Mutations in collagen-like tail subunit gene ( COLQ ) acetylcholinesterase are responsible for recessive forms synaptic congenital syndromes with end plate deficiency. Clinical presentation includes ptosis, ophthalmoparesis, and progressive weakness onset birth or early infancy. Methods We followed 26 patients -CMS over mean period 9...
Objective: Migraine is a debilitating disease affecting large number of young people. In this study, he aim was to assess the extracranial arteries during migraine headaches and non-headache headache intervals using sonography. Materials Methods: The study enrolled 210 patients with confirmed headaches. vertebral arteries, superficial temporal internal carotid (ICAs), common were assessed sonographic method. Grayscale spectral doppler criteria, such as diameter peak systolic velocity (PSV),...
During the COVID-19 pandemic, methanol-containing beverages' consumption has risen because people mistakenly believed that alcohol might protect them against virus. This study aimed to evaluate prevalence and predisposing factors of brain lesions in patients with methanol toxicity its outcome. A total 516 confirmed poisoning were enrolled this retrospective study, which 40 underwent spiral computed tomography (CT) scan. The presence unilateral or bilateral necrosis was significantly higher...
Abstract Background A specific biological vulnerability underlies suicidal behavior. Recent findings have suggested a possible role of inflammation and neuroaxonal injury. However, the relationship between clinical symptoms in this disorder is still unclear. The objective study applying novel blood markers integrity such as neurofilament light chain (NfL) comparing results with healthy control subjects. Methods In cross-sectional patients suicide attempts were evaluated. serum concentration...
Abstract Objective The aim of this research was to investigate the hypothesized association between Toxoplasma gondii infection and idiopathic Parkinson's disease ( IPD ). Methods In present cross‐sectional study, we investigated T. seropositivity in patients comparison with suffering from other neurological diseases (excluding movement disorders) healthy people. Initially, all participants underwent a thorough clinical paraclinical investigation. After this, 5 mL blood taken participants,...
Diagnosis of neuropsychiatric systemic lupus erythematosus (NPSLE) is challenging due to nonspecific biomarkers. High serum levels neurofilament protein light subunit (NFL), high mobility group box 1 (HMGB1), Matrix metalloproteinase-9 (MMP-9) and have been reported in several autoimmune diseases. The aim this study was examine whether their plasma could serve as a diagnostic or prognostic biomarker for NPSLE.
Background Few migraine preventive agents have been assessed in a pediatric population. We evaluated the safety and efficacy of cinnarizine sodium valproate for prophylaxis children adolescents. Methods carried out randomized double-blind placebo-controlled trial Children’s Medical Center Sina hospital, Tehran, Iran. Eligible participants were randomly assigned 1:1:1 ratio via interactive web response system to receive either cinnarizine, valproate, or placebo. The primary endpoints mean...