The far-field microdynamic disturbance caused by the excavation of deep mineral resources and underground engineering can induce surrounding rock damage in high-stress conditions even lead to disasters. However, mechanical properties damage/fracture evolution mechanisms induced under three-dimensional stress states are unclear. Therefore, a true triaxial multilevel test method is proposed, which completely simulate natural geostress, redistribution (such as unloading, concentration...

Due to the existence of true three-dimensional high-geostress in deep underground engineering, rock shows different mechanical properties and brittle–ductile behaviours from conventional triaxial stress states, however, characteristics are not clear. Therefore, a series tests were performed on deeply buried marble investigate effects σ 2 3 characteristic strength (peak strength, yield residual strength), post-peak deformation behaviour. Based test results, elastoplastic damage constitutive...

About a quarter of Chinese wild orchid species are used in traditional medicine or as health food supplements. The market demand for some species, such those the epiphytic genus Dendrobium, has diminished many populations to local extinction dangerously small numbers. Conservation these heavily exploited orchids currently relies on two-pronged approach: establishing nature reserves and encouraging massive commercial cultivation artificial settings. We argue that measures not sufficient...

To specifically deliver cytotoxic drug to tumor cells and enhance cellular uptake is the key for effective cancer therapy. In this paper, we described a novel targeting system, which designed combine features of biological (cell-penetrating peptides, CPPs) physical (magnetic) use in magnetic hyperthermia-triggered release. A doxorubicin-CPPs conjugate (DOX-CPPs) was loaded into thermosensitive liposomes (TSMLs) (DOX-CPPs/TSMLs), vitro DOX-CPPs release activity, anti-proliferation effect,...

A new drug-targeting system for CD13+ tumors has been developed, based on ultrasound-sensitive nanobubbles (NBs) and cell-permeable peptides (CPPs). Here, the CPP-doxorubicin conjugate (CPP-DOX) was entrapped in asparagine–glycine–arginine (NGR) peptide modified NB (CPP-DOX/NGR-NB) penetration of CPP-DOX temporally masked; local ultrasound stimulation could trigger release from activate its penetration. The CPP-DOX/NGR-NBs had particle sizes about 200 nm drug entrapment efficiency larger...

Abstract The forecasted changes in global climate include not only shifts average conditions, but also the frequency and intensity of climatic extremes. One such extreme expected to change future are cold spells. Although these disturbances may become less frequent, spells believed persist foreseeable will likely have profound effects on species distributions, community organization, ecosystem function. However, generalities about how ecosystems respond remain understudied. In 2008, an...

Energy Internet has become the current international frontier and national demand, is key means to achieve cross domain integration collaborative sharing of energy resources. Regional integrated system (RIES) an important form tap complementary capacity different sources promote technology. a three-tier architecture layer, information layer value layer. Based on study conversion mechanism, network interconnection efficiency quality system, path evaluation index for interworking ability...

Abstract Parrotia subaequalis (Hamamelidaceae) is a Tertiary relic species endemic in eastern China. We used inter‐simple sequence repeat ( ISSR ) markers to access genetic diversity and population structure natural five populations of P. . The levels were higher at level H = 0.2031) but lower 0.1096). might be attributed the accumulation distinctive genotypes which adapted different habitats after Quaternary glaciations. Meanwhile, founder effects on early stage, subsequent bottleneck...

Abstract Objectives To enhance the targeting delivery efficiency of small interfering RNA (siRNA) to tumour cells, a novel multifunctional liposome (PSP/NGR-L) comodified with photo-sensitive cell-penetrating peptides (PSP) and asparagine-glycine-arginine peptide (NGR) was constructed investigated. Methods PSP conjugated 1,2-distearoyl-sn-glycero-3-phosphoethanolamine-N-maleimide(polyethylene glycol)-2000 (DSPE-PEG2000-MAL) generate DSPE-PEG2000-PSP used form PSP/NGR-L, features liposomes...

Purpose The purpose of this research study is to explore the influence perceived organizational support (POS) on embeddedness and identification in simulated home environment. Another objective provide an effective cross-cultural adjustment model adopted by many Chinese enterprises operating overseas. Furthermore, it examines mediating effects POS expatriate adjustment. Design/methodology/approach data quantitative was acquired from a questionnaire survey completed 326 expatriates power...

Pseudolarix (Pinaceae) is a vulnerable (sensu IUCN) monotypic genus restricted to southeastern China. To better understand levels of genetic diversity, population structure and gene flow among populations P. amabilis, we developed five compound SSR markers ten novel polymorphic expressed sequence tags (EST) derived microsatellites. The results showed that all 15 loci were with the number alleles per locus ranging from two seven. expected observed heterozygosities varied 0.169 0.752, 0.000...

Abstract NOTE: The first page of text has been automatically extracted and included below in lieu an abstract Problem-solving experience through light dose computational mathematical modules for undergraduate engineering students In this paper, the authors discuss development a framework creating mathematics students. purpose is to introduce concepts modeling real-world applications intended develop students’ ability generalize concept work with models varying abstraction. represent...

The Rubrene-doped organic light emitting diodes were fabricated by doping Rubrene, containing the singlet-triplet energy- resonant property ( E S≈2 T), into phosphorescent-based host materials with different concentrations to investigate their magneto-electroluminescence (MEL). results show that MEL responses, including low field component B ≦5 mT) and high (5 mT ≦ ≦500 mT), change significantly concentration. These curves could be attributed hyperfine interaction, singlet excition fission...

In the past, hydrogen was mostly produced from fossil fuels, causing a certain degree of energy and environmental problems. With development low-carbon systems, renewable production technology has developed rapidly become one focuses research in recent years. However, existing work is still limited by small-scale there lack comprehensive on whole production-storage-transportation-utilization system (PSTUH2S), especially modeling different transportation modes various loads fields. To make up...

Although entrepreneurial well-being is a crucial determinant of the sustainability activities, absence standardized measurement tools has resulted in inconsistent and even contradictory research findings. Thus, this study we explored connotation structure using grounded theory method. In addition, conducted factor analysis to establish an appropriate scale consisting 12 items spanning three dimensions: subjective, psychological, social well-being. The Entrepreneurial WellBeing Scale...

In this study, the mating system of endangered aquatic fern Ceratopteris thalictroides in China was investigated using microsatellite markers. The estimates multilocus outcrossing rate (tm) and single-locus (ts) were high at species level (tm = 0.701 ts 0.595, respectively), indicating that C. is a predominantly species. Negative F (inbreeding coefficient maternal parents) values (-0.137) indicated an excess heterozygotes low inbreeding populations analyzed. Our investigation revealed some...

A dynamic environment monitoring method of power communication room based on IEC 61850 protocol was proposed in this paper and then the system using designed realized. Finally, equipment is realized by unified management scheduling, which improves efficiency operation maintenance. In system, all electric are connected to converter developed project, information with directly uploaded background a scheduling. Besides, achieves county, city provincial management. The has advantages centralized...

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有机太阳能电池(OPV)