A5000997520- Air Quality and Health Impacts
- Global Cancer Incidence and Screening
- Climate Change and Health Impacts
- Topological and Geometric Data Analysis
- COVID-19 impact on air quality
- Noise Effects and Management
- Quantum Electrodynamics and Casimir Effect
- Digital Radiography and Breast Imaging
- Cervical Cancer and HPV Research
- Cosmology and Gravitation Theories
- Markov Chains and Monte Carlo Methods
- AI in cancer detection
- Cancer Risks and Factors
- Stochastic processes and statistical mechanics
- Theoretical and Computational Physics
- Genital Health and Disease
- Black Holes and Theoretical Physics
- Noncommutative and Quantum Gravity Theories
- COVID-19 and healthcare impacts
- Colorectal Cancer Screening and Detection
- Hepatitis B Virus Studies
- Mechanical and Optical Resonators
- Birth, Development, and Health
- Blood Pressure and Hypertension Studies
- Health, Environment, Cognitive Aging
University of Copenhagen
2016-2024
Copenhagen University Hospital
2024
Environmental Health
2024
Regione del Veneto
2019
Lund University
2014-2017
Institute of Mathematical Statistics
2014-2016
Japan External Trade Organization
2012
Istituto Nazionale di Fisica Nucleare, Sezione di Napoli
2008
Early ecological studies have suggested links between air pollution and risk of coronavirus disease 2019 (COVID-19), but evidence from individual-level cohort is still sparse. We examined whether long-term exposure to associated with COVID-19 who most susceptible.
Denmark was one of the few countries where it politically decided to continue cancer screening during COVID-19 pandemic. We assessed actual population uptake mammography and cervical this period.The first lockdown in announced on 11 March 2020. To investigate possible changes activity due pandemic, we analysed data from beginning 2017 until end 2021. A time series analysis carried out discover trends outliers activities period 2017-2021. Data were retrieved governmental pandemic-specific...
Rationale: Air pollution is a major risk factor for chronic cardiorespiratory diseases, affecting the immune and respiratory systems' functionality, but epidemiological evidence in infections remains sparse. Objectives: We aimed to assess association of long-term exposure ambient air with developing new recurrent acute lower (ALRIs), characterized by persistently severe symptoms necessitating hospital contact, identify potential susceptible populations socioeconomic status, smoking, physical...
Background: Attention in the 2000s on importance of mammographic density led us to study screening sensitivity, breast cancer incidence, and associations with risk factors by Danish programs. Here, we summarise our approaches findings. Methods: Dichotomized codes: fatty, equal BI-RADS code 1 part 2, other mixed/dense data from 1990s—were available two counties, codes one region were 2012/13. Density linked vital status, incident cancer, potential factors. We calculated sensitivity combining...
The COVID-19 containment response policies (CRPs) had a major impact on air quality (AQ). These CRPs have been time-varying and location-specific. So far, despite having numerous studies the effect of lockdown AQ, knowledge gap remains association between stringency AQ changes across world, regions, nations, cities. Here, we show that globally 1851 cities (each more than 300 000 people) in 149 countries, after controlling for impacts relevant covariates (e.g., meteorology), Sentinel-5P...
We examined the association of long-term exposure to air pollution and road traffic noise with dementia incidence in Danish Nurse Cohort.
The currently recommended double reading of all screening mammography examinations is an economic burden for programs. sensitivity higher women with low breast density than high density. One may therefore ask whether single could replace at least We addressed this question using data from a program where the radiologists coded their readings independently.Data include in Capital Region Denmark 1 November 2012 to 31 December 2013. Outcome was assessed by linkage Danish Pathology Register....
Background Lolland-Falster is the area of Denmark with highest mortality. However, clinical measurements from a population-based health survey showed prevalence disease indicators similar to those in rest Denmark. The study aimed disentangle this paradox. Methods Health Study (LOFUS) took place 2016–2020. We followed 53 000 invited persons up for mortality invitation date 1 February 2023. Log-binomial regression was used calculate relative risk (RR) non-participation versus participation...
Recent research suggests a link between air pollution and cognitive development in children, studies on academic achievement are emerging. We conducted nationwide cohort study Denmark to explore the associations lifetime exposure performance 9th grade. The encompassed 785,312 children born 1989 2005, all of whom completed 9th-grade exit examinations. Using linear mixed models with random intercept for each school, we assessed relationship 16 years PM2.5, PM10, gaseous pollutants Grade Point...
Recent work in the literature had evaluated energy-momentum tensor of a Casimir apparatus weak gravitational field, for an electromagnetic field subject to perfect conductor boundary conditions on parallel plates. The was then predicted experience tiny push upward direction, and regularized first order acceleration. This analysis made it desirable assess what happens simpler case. For this purpose, present paper studies free, real massless scalar homogeneous Dirichlet Working again constant...
4vHPV vaccination has been tested in randomized controlled trials under almost ideal conditions, and studies of real-life use have compared outcome between vaccinated unvaccinated women from the same birth cohort mostly before screening age. Here we present first-to our knowledge-evaluation impact real life without selection bias reported data. The study carried out by comparing results after first cervical an HPV-vaccinated cohort, consisting born Denmark 1993 1983, respectively. Cytology...
Objectives The purposes of the present study were to determine association between (1) 10 individual biomarkers and all-cause mortality; (2) allostatic load (AL), across three physiological systems (cardiovascular, inflammatory, metabolic) mortality. Design Prospective cohort study. Setting We used data from Lolland-Falster Health Study undertaken in Denmark 2016–2020 on systolic blood pressure (SBP) diastolic (DBP), pulse rate (PR), waist–hip ratio (WHR) levels low-density lipoprotein...
Early studies reported a 4- to 6-fold risk of breast cancer between women with extremely dense and fatty breasts. As most early were case-control studies, we took advantage population-based screening program study density incidence in cohort design. In the Capital Region, Denmark, aged 50 69 are invited biennially. Women screened November 2012 December 2017 included, classified by BI-RADS code, version 4, at first screen after recruitment. followed up for incident cancer, including ductal...
Abstract STUDY QUESTION Is the risk of high-grade precancerous cervical lesions and/or is lesion progression increased in users a hormone-containing intrauterine device (HIUD) compared with other contraceptive methods. SUMMARY ANSWER Women starting use HIUD had same subsequent intraepithelial neoplasia 3+ (CIN3+) as copper IUD (CIUD) users, and both groups tended to have lower risks than oral contraceptives (OC) users. WHAT IS KNOWN ALREADY HIUDs may cause inflammatory immunosuppressive...
Abstract Cervical cancer is a preventable disease. Nevertheless, stagnation has been seen in incidence rates also countries with well‐functioning healthcare. On this basis, we investigated associations between control interventions and changes cervical Denmark from 2009 to 2022. Data on human papillomavirus (HPV)‐vaccination were retrieved Staten's Serum Institute; screening recommendations Danish Health Authority, performance Quality Database for Screening; Nordcan Cancer Register. We...
Assessing a woman’s risk of breast cancer is important for personalized screening. Mammographic density strong factor cancer, but parenchymal texture patterns offer additional information which cannot be captured by density. We aimed to combine BI-RADS score 4th Edition and deep-learning-based stratify women in screening compare rates among the combinations. This retrospective study cohort included 216,564 from Danish populations-based program. Baseline mammograms were evaluated using scores...
Abstract Introduction It is pertinent to evaluate the impact of vaccination against human papillomavirus (HPV) in real life. The aim study was real‐life HPV first birth cohort Danish women offered free as girls and invited screening at age 23 years. Material methods Women born 1993 were 15 years but 1983 have never been vaccination. We followed these two cohorts for 10 from after their invitation screening, compared risk high‐grade cervical intraepithelial neoplasia (CIN). Data obtained...
Abstract Background This study aimed to investigate prevalence and risk factors for prediabetes, undiagnosed diabetes mellitus, poorly potentially sub-controlled in a rural-provincial general adult population Denmark. Methods Using cross-sectional data from the Lolland-Falster Health Study, we examined total of 10,895 individuals aged 20 years above. Results Prevalence prediabetes was 5.8% (men: 6.1%; women: 5.5%); 0.8% 1.0%; 0.5%); controlled 1.2% 1.5%; 0.8%); 2% 3.0%; 1.3%). In total, 9.8%...
We consider a Casimir apparatus consisting of two perfectly conducting parallel plates, subject to the weak gravitational field Earth. The aim this paper is calculation energy-momentum tensor system for free, real massless scalar satisfying Neumann boundary conditions on plates. small gravity acceleration (considered here as not varying between plates) allows us perform all calculations first order in parameter. Some interesting results are found: correction, depending acceleration,...
Abstract Background Although breast cancer screening reduces mortality at the population level, subgroups of women may benefit differently. We investigated impact health status on effect screening. Methods The study included 181 299 invited in two population‐based programs Denmark and 1 526 446 control subjects, followed from April 1981 to December 2014. Poisson regressions were used compare observed rate with expected absence among without chronic diseases. Chronic diseases defined as any...
Abstract Introduction Service breast cancer screening is difficult to evaluate because there no unscreened control group. Due a natural experiment, where 20% of women were offered in two regions up 17 years before other women, Denmark unique position. We utilized this opportunity assess outcome service screening. Materials and methods Screening was Copenhagen from 1991 Funen 1993 aged 50–69 years. used difference-in-differences methodology with study group screening; historical group;...
High mammographic density is a well-known risk factor for breast cancer. This study aimed to search possible birth cohort effect on density, which might contribute explain the increasing cancer incidence. We separately analyzed left and right of Dutch women from 13-year period (2003-2016) in screening programme. First, we age-specific changes average percent dense volume (PDV) across cohorts. A linear regression analysis (PDV vs. year birth) indicated small but statistically significant...