Abstract Crowdsourced psychological and other biobehavioral research using platforms like Amazon’s Mechanical Turk (MTurk) is increasingly common – but has proliferated more rapidly than studies to establish data quality best practices. Thus, this study investigated whether outcome scores for three screening tools would be significantly different among MTurk workers who were subject sets of control checks. We conducted a single-stage, randomized controlled trial with equal allocation each...

To assess the effects of Bifidobacteriumlongum subsp. infantis EVC001 (Binfantis EVC001) administration on incidence necrotizing enterocolitis (NEC) in preterm infants a single level IV neonatal intensive care unit (NICU).Nonconcurrent retrospective analysis 2 cohorts very low birth weight (VLBW) not exposed and to Binfantis probiotic at Oregon Health & Science University from 2014 2020. Outcomes included NEC NEC-associated mortality, including subgroup extremely (ELBW) infants. Log-binomial...

Trust in science meaningfully contributes to our understanding of people's belief misinformation and their intentions take actions prevent COVID-19. However, no experimental research has sought intervene on this variable develop a scalable response the COVID-19 infodemic.

Although general principles related to vaccination hesitancy have been well researched, reports on reluctance be vaccinated for coronavirus disease 2019 (COVID-19) in the United States are somewhat surprising, given disease's substantive disruption of everyday life. However, landscape which people making COVID-19 decisions has recently evolved with releases encouraging vaccine-related data and changes official messaging about virus. Therefore, this study sought identify factors associated...

Abstract Background Overdose education and naloxone distribution (OEND) to laypersons are key approaches reduce the incidence of opioid-involved overdoses. While some research has examined attitudes toward OEND, especially among pharmacists first responders, our understanding what believe about overdose is surprisingly limited. Further, scholars have expressed concerns prevalence non-evidence-based beliefs naloxone. We designed this study analyze prevalence, nature, context U.S. laypersons....

Objectives In two large university affiliated healthcare systems, we examined trends in colorectal cancer (CRC) screening both prior to and during the COVID-19 pandemic compare non-invasive tests colonoscopy. Materials methods this retrospective time-trend analysis, obtained numbers of colonoscopies performed monthly year it. We colonoscopy data from five endoscopy units with indication determined by dual independent review. Monthly completed fecal immunochemical (FIT) FIT-DNA were...

Background: Despite the well-established physical benefits of resistance training (RT), only 31% U.S. adults meet RT guidelines, with women participating at lower rates. While physiological aspects are well researched, less is known about psychological factors, such as affective responses (e.g., enjoyment, energy). This study explored relationships between self-efficacy, self-determined motivation, responses, and adherence in a 16-week barbell-based program. Methods: A prospective...

Clustering effects, such as those introduced by housing animals in shared cages, are often overlooked preclinical lifespan studies, despite their potential to distort variance estimates and inflate Type I error rates, leading misleading conclusions. This methodological oversight reduces statistical rigor may undermine the reliability of findings. To address this gap, current study examines impact accounting for clustering nesting effects on analyses comparing results models which both...

Background: Cancer cachexia is a severe metabolic disorder characterized by progressive weight loss along with dramatic in skeletal muscle and adipose tissue. Like cancer, progresses stages starting pre-cachexia to finally refractory cachexia. In the stage, patients are no longer responsive therapy management of possible. It therefore critical detect as early this study we applied metabolomics approach search for biomarkers Methods: Multi-platform analyses were murine Colon-26 (C26) model...

In healthcare and related fields, there is often a gap between research practice. Scholars have developed frameworks to support dissemination implementation of best practices, such as the Interactive Systems Framework for Dissemination Implementation, which shows how scientific innovations are conveyed practitioners through tools, training, technical assistance (TA). Underpinning those aspects model evaluation continuous quality improvement (CQI). However, recent meta-analysis suggests that...

As the COVID-19 pandemic continues to affect life in United States, important role of nonpharmaceutical preventive behaviors (such as wearing a face mask) reducing risk infection has become clear. During pandemic, researchers have observed rapid proliferation misinformed or inconsistent narratives about COVID-19. There is growing evidence that such are associated with various forms undesirable behavior (eg, burning down cell towers). Furthermore, individuals' adherence recommended guidelines...

Background Schools increasingly prioritize social-emotional competence and bullying cyberbullying prevention, so the development of novel, low-cost, high-yield programs addressing these topics is important. Further, rigorous assessment interventions prior to widespread dissemination crucial. Objective This study assesses effectiveness implementation fidelity ACT Out! Social Issue Theater program, a 1-hour psychodramatic intervention by professional actors; it also measures students’...

Abstract Introduction Interstitial lung disease encompasses a group of rare conditions causing inflammation and scarring tissue. The typical method monitoring activity is through pulmonary function tests performed in hospital setting. However, accessing care can be difficult for rural patients due to numerous barriers. This study assesses the feasibility acceptability home spirometry telemonitoring using MIR-Spirometers patientMpower home-monitoring platform with interstitial disease....

Cancer is the leading cause of death for Hispanics in USA. Screening and prevention reduce cancer morbidity mortality.This study administered a cross-sectional web-based survey to self-identified Hispanic residents state Indiana assess their cancer-related knowledge, beliefs, behaviors, as well identify what factors might be associated with screening prevention. Chi-square Fisher's exact test were used compare associations logistic regression develop both univariate multivariate models.A...

Purpose: Given the importance of inspiratory phonation for assessment vocal fold structure, aim this investigation was to evaluate and describe vibratory characteristics using high-speed videoendoscopy in healthy volunteers. The study also examined empirical relationship between cepstral peak prominence (CPP) glottal area waveform measurements derived from simultaneous audio recordings. Method: Vocally adults (33 women, 28 men) volunteered completed videoendoscopic function two trials an...

Metabolomics involves the comprehensive measurement of metabolites from a biological system.The resulting metabolite profiles are influenced by genetics, lifestyle, stresses, disease, diet and environment therefore provides more holistic readout pathological condition organism (Beger et al., 2016;Wishart, 2016).The challenge for metabolomics is that no single analytical platform can provide truly coverage metabolome.The most commonly used platforms based on mass-spectrometry (MS) nuclear...

Abstract Background Retinopathy of prematurity (ROP) is a disease that affects preterm infants born younger than 30 weeks gestation. The pathophysiology ROP involves an initial vaso-obliterative phase followed by vaso-proliferative leads to progression. use supplemental oxygen during the has been associated with reduced progression, but how this impacts need for treatment unclear. goal study was compare rate laser or intravitreal bevacizumab after implementation new therapy protocol in stage...