Xiwei Chen

ORCID: 0000-0003-1868-8387
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Research Areas
  • Obesity, Physical Activity, Diet
  • Statistical Methods and Inference
  • Wound Healing and Treatments
  • Statistical Methods and Bayesian Inference
  • Statistical Methods in Clinical Trials
  • Diet and metabolism studies
  • Nutritional Studies and Diet
  • Poverty, Education, and Child Welfare
  • Seismic Imaging and Inversion Techniques
  • Global Maternal and Child Health
  • Dietary Effects on Health
  • Seismic Waves and Analysis
  • Advanced Statistical Methods and Models
  • Muscle metabolism and nutrition
  • Meta-analysis and systematic reviews
  • Eating Disorders and Behaviors
  • Mass Spectrometry Techniques and Applications
  • Antimicrobial agents and applications
  • Breast Cancer Treatment Studies
  • Pain Management and Placebo Effect
  • Medical and Biological Ozone Research
  • Prostate Cancer Treatment and Research
  • Obesity and Health Practices
  • Immunotherapy and Immune Responses
  • Radiomics and Machine Learning in Medical Imaging

Indiana University Bloomington
2018-2025

Jinan University
2017-2024

Taizhou People's Hospital
2022-2024

Yangzhou University
2022-2024

Nantong University
2022-2024

China Institute of Atomic Energy
2024

Lewis University
2023

Ten Chen Hospital
2023

Alkermes (United States)
2023

Indiana University
2021-2023

Developing an ideal wound dressing that meets the multiple demands of good biocompatibility, appropriate porous structure, superior mechanical property and excellent antibacterial activity against drug-resistant bacteria is highly desirable for clinical care. Biocompatible thermoplastic polyurethane (TPU) membranes are promising candidates as a scaffold; however, their lack suitable structure has limited application. Antibiotics generally used preventing bacterial infections, but global...

10.1186/s12951-018-0416-4 article EN cc-by Journal of Nanobiotechnology 2018-11-12

Standard treatment for metastatic prostate cancer (CaP) prevents ligand-activation of androgen receptor (AR). Despite initial remission, CaP progresses while relying on AR. AR transcriptional output controls behavior and is an alternative therapeutic target, but its molecular regulation poorly understood. Here, we show that action activated partitions into fractions are controlled preferentially by different coregulators. In a 452-AR-target gene panel, each 18 clinically relevant...

10.7554/elife.28482 article EN cc-by eLife 2017-08-18

Trust in science meaningfully contributes to our understanding of people's belief misinformation and their intentions take actions prevent COVID-19. However, no experimental research has sought intervene on this variable develop a scalable response the COVID-19 infodemic.

10.2196/32425 article EN cc-by Journal of Medical Internet Research 2021-09-28

This cohort study examines the association between COVID-19 pandemic restrictions and obesity prevalence among youths aged 2 to 19 years in Monroe County, Indiana.

10.1001/jamanetworkopen.2023.23596 article EN cc-by-nc-nd JAMA Network Open 2023-07-14

Background Cash transfers are a promising but understudied intervention that may protect cognitive function in adults. Although South Africa has rapidly ageing population, little is known about the nature of association between cash and this setting. Objectives We leveraged age-eligibility expansions to Africa’s Child Support Grant (CSG) investigate duration CSG eligibility biological mothers child beneficiaries Africa. Methods analysed 2014/2015 baseline data from 944 women, aged 40–59...

10.1371/journal.pone.0297673 article EN cc-by PLoS ONE 2024-03-06

Abstract Objective Food noise has received attention in the media, although no validated questionnaires exist to measure it. This study developed and tested reliability validity of Noise Questionnaire (FNQ). Methods Participants ( N = 400) successfully completed, FNQ a demographic questionnaire self‐reported weight height. A subsample n 150) completed 7 days later for test–retest reliability, this subsample's first data were subjected exploratory factor analysis. The remaining 250) two...

10.1002/oby.24216 article EN cc-by-nc-nd Obesity 2025-01-19

To estimate the likelihood of upgrade for atypical ductal hyperplasia (ADH) diagnosed on a core needle biopsy mammographically detected lesion.A total 203 consecutive ADH cases in lesions and having subsequent surgical excision were reviewed. The pathological features assessed with multivariable logistic regression to predict these patients. A nomogram was created using statistically significant variables. corresponding formula calculate risk upgrade. This divided further into low,...

10.1111/his.12635 article EN Histopathology 2014-12-19

The concept of the Internet Things (IoT) is an important part next generation information. Wireless sensor networks are composed independent distributed smart nodes and gateways. These discrete sensors constantly gather external physical information, such as temperature, sound, vibration. Owing to diversity devices complexity sensing environment, direct modeling IoT-aware business process application particularly difficult. In addition, how effectively deploy those designed applications...

10.3390/s19010111 article EN cc-by Sensors 2018-12-30

Early life exposure to environmental lead (Pb) has been linked decreased IQ, behavior problems, lower lifetime earnings, and increased criminal activity. Beginning in the 1970s, limits on Pb paint, gasoline, food cans, regulated water utilities sharply curtailed US exposure. Nonetheless, hundreds of thousands children remain at risk. This study reports how unregulated private well is an underrecognized source that associated with risk teenage juvenile delinquency. We build a longitudinal...

10.1073/pnas.2110694119 article EN cc-by-nc-nd Proceedings of the National Academy of Sciences 2022-01-31

Standard single-agent nonplatinum chemotherapy provides only modest benefit in a small proportion of patients with platinum-resistant/-refractory ovarian cancer, objective response rates 6-20% and progression-free survival ≈3-4 months. Nemvaleukin alfa (nemvaleukin, ALKS 4230) is novel cytokine designed to capture expand the therapeutic potential high-dose interleukin-2 (IL-2) while mitigating its associated toxicity issues. preferentially activates cytotoxic CD8

10.2217/fon-2023-0246 article EN cc-by-nc-nd Future Oncology 2023-06-19

To identify variables that can predict upgrade for magnetic resonance imaging (MRI)-detected atypical ductal hyperplasia (ADH).We reviewed 1655 MRI-guided core biopsies between 2005 and 2013, yielding 100 (6%) cases with ADH. The pathological features of ADH MRI findings were recorded. An was considered when the subsequent surgical excision yielded invasive carcinoma (IC) or in situ (DCIS). rate institutions 3.3-7.1%, an average 6%. A total 15 (15%) had upgrade, 12 DCIS three IC. When all...

10.1111/his.12811 article EN Histopathology 2015-08-20

Abstract Dietary restriction (DR) was reported to either have no effect or reduce the lifespan of majority 41‐recombinant inbred (RI) lines studied by Liao et al. ( Aging Cell , 2010, 9 92). In an appropriately power longevity study n > 30 mice/group), we measured four RI (115‐RI, 97‐RI, 98‐RI, and 107‐RI) that were greatest decrease in when fed 40% DR. DR increased median female RI‐115, 107‐RI mice male 115‐RI mice. had little (<4%) on 98‐RI 97‐RI reduced over 20%. While our unable...

10.1111/acel.13500 article EN Aging Cell 2021-10-29

Two-thirds of people living with Alzheimer's disease and related dementias (ADRD) live in low- middle-income countries, this figure is expected to rise as these populations are rapidly aging. Since evidence demonstrates links between socioeconomic status slower rates cognitive decline, protecting older adults' function resource-limited countries that lack the infrastructure cope ADRD crucial reduce burden it places on their health systems. While cash transfers a promising intervention...

10.1080/08959420.2023.2195785 article EN Journal of Aging & Social Policy 2023-03-28

Adolescence represents a crucial period for sexual and romantic relationship development, acquisition of skills confidence essential effective consent communication. However, various barriers may interfere with adolescents' belief in their ability (i.e., self-efficacy) to negotiate practice. This study aimed investigate the state self-efficacy ask explore influence communication (a construct comprised three characteristics: assertiveness skills, positive conflict resolution, awkwardness)....

10.1080/00224499.2024.2306475 article EN The Journal of Sex Research 2024-01-31

Background: Hypertrophic scar is an excessive healing response that often follows thermal injury. The most outstanding morphologic change the overdeposition of collagen, which caused by imbalance between synthesis and metabolism collagen. Previous studies also found transforming growth factor-β was key factor controlling formation. However, neither anti–transforming nor other methods could completely control formation contraction. This fact suggests a multifactorial cause. Fortunately, cDNA...

10.1097/01.ta.0000108997.49513.dc article EN Journal of Trauma and Acute Care Surgery 2004-12-01

Pathology-generated equations have been introduced to predict Oncotype DX recurrence score (ORS) in breast cancer. The purpose of the study is improve these equations.Slides from 416 (test set) consecutive cancers with available were reviewed. A validation set (n=91) was prospectively scored using generated formulas test set. following histopathologic features graded: Nottingham grade (designated as current grade), necrosis, and degree tumor-infiltrating lymphocytes. data extracted pathology...

10.1097/pai.0000000000000248 article EN Applied immunohistochemistry & molecular morphology 2016-01-24

Breast cancer has been suggested to potentially have prenatal origins. We examined associations between birth weight, body mass index (BMI) at four-time points over 25 years of adulthood, and risk postmenopausal breast cancer, with emphasis on whether the association weight was mediated by height changes adult life course. Postmenopausal women (n = 70,397) aged 50-79 without enrollment (1993-1998) were followed up years. Weight measured baseline. Birth weights ages 18, 35 50 self-reported....

10.1002/ijc.32710 article EN International Journal of Cancer 2019-10-04

Dysphagia is a common side effect of anticancer treatments in patients with head and neck cancer (HNC) can worsen patients' quality life. A well-established measure essential to evaluate dysphagia HNC patients.The aim this study determine the psychometric properties Chinese version M.D. Anderson Inventory (MDADI-C) for patients.A total 220 subjects were included study. Reliability was examined by internal consistency (Cronbach's α) test-retest reliability (intraclass correlation...

10.1097/ncc.0000000000000397 article EN Cancer Nursing 2016-05-28

ABSTRACT Objective Autonomic regulation of organ and tissues may give rise to disruptions typical functions. The Body Perception Questionnaire Short Form (BPQ-SF) includes items that were developed assess autonomic symptoms in daily life. This pair studies aimed establish previously unexplored psychometric properties the BPQ-SF scale, develop normative values for clinical research use, convergence self-reports with sensor-based measures. Methods Study 1 reports exploratory confirmatory...

10.1097/psy.0000000000001250 article EN Psychosomatic Medicine 2023-09-06
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