A5011499064- Essential Oils and Antimicrobial Activity
- Coccidia and coccidiosis research
- Gut microbiota and health
- Inflammatory Bowel Disease
- Ginger and Zingiberaceae research
- Parasitic Infections and Diagnostics
- Polysaccharides and Plant Cell Walls
- Heat shock proteins research
- Advanced Drug Delivery Systems
- Animal Nutrition and Physiology
- Barrier Structure and Function Studies
- Milk Quality and Mastitis in Dairy Cows
- Antibiotic Resistance in Bacteria
- Viral gastroenteritis research and epidemiology
- Tea Polyphenols and Effects
- Veterinary medicine and infectious diseases
- Liver Disease Diagnosis and Treatment
- Cancer-related molecular mechanisms research
- T-cell and Retrovirus Studies
- Phytochemicals and Antioxidant Activities
- Antimicrobial agents and applications
- Probiotics and Fermented Foods
- Pomegranate: compositions and health benefits
- Liver Diseases and Immunity
- RNA modifications and cancer
Yangzhou University
2017-2025
Changsha Central Hospital
2021-2023
Beijing Hospital of Traditional Chinese Medicine
2023
Capital Medical University
2023
University of South China
2021
University of Electronic Science and Technology of China
2021
First Affiliated Hospital of GuangXi Medical University
2020
Guangxi Medical University
2020
China Agricultural University
2014-2015
Reactive oxygen species (ROS) and oxidative stress are thought to play a central role in potentiating macrophage activation, causing excessive inflammation, tissue damage, sepsis. Recently, we have shown that punicalagin (PUN) exhibits anti-inflammatory activity LPS-stimulated macrophages. However, the potential antioxidant effects of PUN macrophages remain unclear. Revealing these will help understand mechanism underlying its ability inhibit activation. Hemeoxygenase-1 (HO-1) Therefore,...
To develop an environmentally sustainable and efficient extraction method for flavonoids from Moringa oleifera Lam. (M. oleifera) leaves, natural deep eutectic solvents (NADES) with ultrasound-assisted was utilized in this study. After optimization of parameters NADES, including ultrasonic power, time, liquid–solid ratio, the yield NADES (UAN) composed betaine urea (Bet-Urea) reached 54.69 ± 0.19 mg RE/g DW, which made a 1.7-fold increase compared to traditional solvent (UATS). UPLC-Q...
Endoplasmic reticulum (ER) stress may contribute to the pathogenesis and perpetuation of ulcerative colitis (UC). Previous studies have shown artesuante (ARS) has protective effect on experimental UC. Therefore, it can be assumed that ARS regulate ER its related reactions. Dextran sulfate sodium (DSS) induced UC model in mice was used testify this hypothesis. The results clearly showed DSS exposure caused excessive evidenced by a markedly increase GRP78 CHOP expression, then activated...
In bovine mammary epithelial cells (BMECs), a cascade of inflammatory reactions induced by lipopolysaccharide (LPS) has been shown to result in cell injury and apoptosis. The present study aims reveal the protective effect ferulic acid (FA) on LPS-induced BMEC apoptosis explore its potential molecular mechanisms. First, we showed that FA had low cytotoxicity BMECs significantly decreased proinflammatory response LPS. Next, blocked oxidative stress restoring balance redox state inhibiting...
Salmonella enterica serovar Typhimurium (S. Typhimurium) continues to be a serious concern the poultry industry as bacterial foodborne zoonosis, which generally results in intestinal inflammation and barrier dysfunction or even death. Eugenol is phenolic compound with various pharmacological activities involved antioxidant, anti-inflammatory, antibacterial effects, expected an effective nonantibiotic therapy. The purpose of this study was explore protective effects eugenol cellular broiler...
Crohn’s disease (CD) is an inflammatory bowel characterized by chronic inflammation of the entire digestive lining. Although pathogenesis CD remains unclear, multiple factors especially altered microbiota are among its causes. In this study, experimental model was established TNBS-enema. Then dynamic changes colonic tissue lesions, tight junctions, response, and oxidative stress respectively tested H&E staining, immunofluorescence commercial kits. 16S rRNA ITS sequencing feces were...
Extensive efforts are underway to overcome the rising prevalence of antibiotic resistance. Combination therapy may be a potential method treat multidrug-resistant (MDR) bacterial infections. In this study, tea tree essential oil (TTO) nanoemulsion (nanoTTO) was used in combination with antibiotics kill microbes. Results showed that nanoTTO enhanced activities multiple against MDR Escherichia coli (E. coli), and its antimicrobial activity not changed bacteria were cultured presence for 30...
The characteristic of ulcerative colitis (UC) is extensive colonic mucosal inflammation. Moringa oleifera ( M. ) a medicine food homology plant, and the polysaccharide from leaves (MOLP) exhibits antioxidant anti-inflammatory activity. aim this study to investigate potential effect MOLP on UC in mouse model as well underlying mechanism. Dextran sulfate sodium (DSS) 4% drinking water was given for 7 days mice with UC, at same time, (25, 50, 100 mg/kg/day) intragastric administered once daily...
In our previous study, lipopolysaccharide (LPS) significantly reduced the cell viability of primary bovine mammary epithelial cells (bMEC) leading to apoptosis, which were prevented by caffeic acid (CA) through inhibiting NF- κ B activation and reducing proinflammatory cytokine expression. While underlying mechanism remains unclear, here, we determined that LPS induced extensive microstructural damage bMEC, especially mitochondria endoplasmic reticulum. Then, obvious reduction mitochondrial...