- Congenital Diaphragmatic Hernia Studies
- Congenital Anomalies and Fetal Surgery
- Cerebrospinal fluid and hydrocephalus
- Esophageal and GI Pathology
- Spinal Dysraphism and Malformations
- Neonatal Respiratory Health Research
- Hernia repair and management
- Intestinal Malrotation and Obstruction Disorders
- Prenatal Screening and Diagnostics
- Child Abuse and Related Trauma
- Congenital gastrointestinal and neural anomalies
- Child Abuse and Trauma
- Appendicitis Diagnosis and Management
- Cardiac Structural Anomalies and Repair
- Cardiac and Coronary Surgery Techniques
- Grief, Bereavement, and Mental Health
- Helicobacter pylori-related gastroenterology studies
- Biliary and Gastrointestinal Fistulas
- Cardiac Valve Diseases and Treatments
- Maternal and Perinatal Health Interventions
- Homicide, Infanticide, and Child Abuse
- Fetal and Pediatric Neurological Disorders
- Family and Disability Support Research
- Surgical Simulation and Training
- Organ and Tissue Transplantation Research
Yale University
2018-2023
Hartwell Foundation
2022
Case Western Reserve University
2022
Yale New Haven Hospital
2022
Chase Acute Outpatients Hospital
2021
University of Maryland, Baltimore
2015-2018
Evidence that reports to child protective services1 and emergency department visits2 for maltreatment have decreased during the coronavirus disease 2019 (COVID-19) pandemic has led concerns children are being maltreated but not brought care. We hypothesized in case of potentially life-threatening abuse, such as abusive head trauma (AHT), it is more difficult caregivers forgo medical A standard approach estimating occurrence AHT been counting hospitalizations.3 Therefore, comparing...
Structural fetal diseases, such as congenital diaphragmatic hernia (CDH) can be diagnosed prenatally. Neonates with CDH are healthy in utero gas exchange is managed by the placenta, but impaired lung function results critical illness from time a baby takes its first breath. MicroRNA (miR) 200b and downstream targets TGF-β pathway critically involved branching morphogenesis. Here, we characterize expression of miR200b at different gestational times using rat model CDH. Fetal rats deficient...
Importance Several studies have demonstrated a decrease in the occurrence of child abuse US since start COVID-19 pandemic. This finding has generated concern for missed cases due to initial lockdowns and lack childcare resources. Determining association pandemic on hospitalizations severe forms is essential focus preventive efforts. Objective To examine trends abusive head trauma (AHT) before during Design, Setting, Participants Retrospective, multicenter, repeated cross-sectional study,...
To compare institutional practice patterns for gastrostomy tube placement in neonates with duodenal atresia (DA) and trisomy 21.A retrospective review of the Pediatric Health Information System (PHIS) from 2015 to 2018 identified infants <10 days old ICD-10 diagnostic codes DA 21, addition procedure an intestinal bypass or duodenoduodenostomy. This cohort was then queried associated co-morbidities.Two hundred nine were DA, bypass. Fifty-seven (27%) underwent placement. Baseline...
Despite a national decrease in emergency department visits the United States during first 10 months of pandemic, preliminary Consumer Product Safety Commission data indicate increased firework-related injuries. We hypothesized an increase injuries 2020 compared to years prior related corresponding consumer firework sales.The National Electronic Injury Surveillance System (NEISS) was queried from 2018 for cases with product codes 1313 (firework injury) and narratives containing "fireworks"....
Neural tube defects are a common congenital anomaly involving incomplete closure of the spinal cord. Myelomeningocele (MMC) is severe form in which there complete exposure neural tissue with lack skin, soft tissue, or bony covering to protect The all-trans retinoic acid (ATRA) induced rat model reproducible, cost-effective means studying this disease; however, limited modalities objectively quantify disease severity, potential benefits from experimental therapies. We sought determine...
Although rectal biopsy has long been established as the criterion standard for diagnosis of Hirschsprung disease, little to no information exists regarding nationwide rates positivity or interinstitutional variability. We sought determine national rate and factors contributing institutional variability.A retrospective review Children's Hospital Association's (CHA) Pediatric Health Information System from 2009 2018 identified infants <100 days old with ICD-9/ICD-10 procedural codes in...
Abstract Structural fetal diseases, such as congenital diaphragmatic hernia (CDH) can be diagnosed prenatally. Neonates with CDH are healthy in utero gas exchange is managed by the placenta, but impaired lung function results critical illness from time a baby takes its first breath. During development, lungs capable of remarkable growth and fetus does not yet require for exchange. MicroRNA (miR) 200b downstream targets TGFβ pathway critically involved branching morphogenesis. Here we...